BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

196 related articles for article (PubMed ID: 27757735)

  • 1. Amsacrine-induced apoptosis of human leukemia U937 cells is mediated by the inhibition of AKT- and ERK-induced stabilization of MCL1.
    Lee YC; Chen YJ; Huang CH; Chang LS
    Apoptosis; 2017 Mar; 22(3):406-420. PubMed ID: 27757735
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NOXA-mediated degradation of MCL1 and BCL2L1 causes apoptosis of daunorubicin-treated human acute myeloid leukemia cells.
    Chiou JT; Huang NC; Huang CH; Wang LJ; Lee YC; Shi YJ; Chang LS
    J Cell Physiol; 2021 Nov; 236(11):7356-7375. PubMed ID: 33982799
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The suppressive effect of arsenic trioxide on TET2-FOXP3-Lyn-Akt axis-modulated MCL1 expression induces apoptosis in human leukemia cells.
    Chen YJ; Huang CH; Shi YJ; Lee YC; Wang LJ; Chang LS
    Toxicol Appl Pharmacol; 2018 Nov; 358():43-55. PubMed ID: 30213730
    [TBL] [Abstract][Full Text] [Related]  

  • 4. GSK3β suppression inhibits MCL1 protein synthesis in human acute myeloid leukemia cells.
    Lee YC; Shi YJ; Wang LJ; Chiou JT; Huang CH; Chang LS
    J Cell Physiol; 2021 Jan; 236(1):570-586. PubMed ID: 32572959
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Quinacrine induces apoptosis in human leukemia K562 cells via p38 MAPK-elicited BCL2 down-regulation and suppression of ERK/c-Jun-mediated BCL2L1 expression.
    Changchien JJ; Chen YJ; Huang CH; Cheng TL; Lin SR; Chang LS
    Toxicol Appl Pharmacol; 2015 Apr; 284(1):33-41. PubMed ID: 25684043
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Naja nigricollis CMS-9 enhances the mitochondria-mediated death pathway in adaphostin-treated human leukaemia U937 cells.
    Chen YJ; Wang JJ; Chang LS
    Clin Exp Pharmacol Physiol; 2011 Nov; 38(11):755-63. PubMed ID: 21824174
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Farnesyltransferase inhibitors interact synergistically with the Chk1 inhibitor UCN-01 to induce apoptosis in human leukemia cells through interruption of both Akt and MEK/ERK pathways and activation of SEK1/JNK.
    Dai Y; Rahmani M; Pei XY; Khanna P; Han SI; Mitchell C; Dent P; Grant S
    Blood; 2005 Feb; 105(4):1706-16. PubMed ID: 15494423
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ONC212 enhances YM155 cytotoxicity by triggering SLC35F2 expression and NOXA-dependent MCL1 degradation in acute myeloid leukemia cells.
    Chiou JT; Chang LS
    Biochem Pharmacol; 2024 Jun; 224():116242. PubMed ID: 38679209
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cytarabine-induced destabilization of MCL1 mRNA and protein triggers apoptosis in leukemia cells.
    Chiou JT; Hsu CC; Hong YC; Lee YC; Chang LS
    Biochem Pharmacol; 2023 May; 211():115494. PubMed ID: 36924905
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CREB/Sp1-mediated MCL1 expression and NFκB-mediated ABCB1 expression modulate the cytotoxicity of daunorubicin in chronic myeloid leukemia cells.
    Chiou JT; Huang CH; Wu TH; Wang LJ; Lee YC; Huang PW; Chang LS
    Toxicol Appl Pharmacol; 2022 Jan; 435():115847. PubMed ID: 34963561
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ABT-263-induced MCL1 upregulation depends on autophagy-mediated 4EBP1 downregulation in human leukemia cells.
    Lee YC; Wang LJ; Huang CH; Shi YJ; Chang LS
    Cancer Lett; 2018 Sep; 432():191-204. PubMed ID: 29913235
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression of the antiapoptotic MCL1 gene product is regulated by a mitogen activated protein kinase-mediated pathway triggered through microtubule disruption and protein kinase C.
    Townsend KJ; Trusty JL; Traupman MA; Eastman A; Craig RW
    Oncogene; 1998 Sep; 17(10):1223-34. PubMed ID: 9771965
    [TBL] [Abstract][Full Text] [Related]  

  • 13. BCL2L1 inhibitor A-1331852 inhibits MCL1 transcription and triggers apoptosis in acute myeloid leukemia cells.
    Chiou JT; Wu YY; Lee YC; Chang LS
    Biochem Pharmacol; 2023 Sep; 215():115738. PubMed ID: 37562509
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Involvement of Ras/extracellular signal-regulated kinase, but not Akt pathway in risedronate-induced apoptosis of U937 cells and its suppression by cytochalasin B.
    Fujita H; Utsumi T; Muranaka S; Ogino T; Yano H; Akiyama J; Yasuda T; Utsumi K
    Biochem Pharmacol; 2005 Jun; 69(12):1773-84. PubMed ID: 15869745
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Kaempferol induces cell death through ERK and Akt-dependent down-regulation of XIAP and survivin in human glioma cells.
    Jeong JC; Kim MS; Kim TH; Kim YK
    Neurochem Res; 2009 May; 34(5):991-1001. PubMed ID: 18949556
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synergistic cytotoxicity of decitabine and YM155 in leukemia cells through upregulation of SLC35F2 and suppression of MCL1 and survivin expression.
    Chiou JT; Chang LS
    Apoptosis; 2024 Apr; 29(3-4):503-520. PubMed ID: 38066391
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ROS-mediated p38alpha MAPK activation and ERK inactivation responsible for upregulation of Fas and FasL and autocrine Fas-mediated cell death in Taiwan cobra phospholipase A(2)-treated U937 cells.
    Liu WH; Cheng YC; Chang LS
    J Cell Physiol; 2009 Jun; 219(3):642-51. PubMed ID: 19180563
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tyrosine Kinase Inhibitors Increase MCL1 Degradation and in Combination with BCLXL/BCL2 Inhibitors Drive Prostate Cancer Apoptosis.
    Arai S; Jonas O; Whitman MA; Corey E; Balk SP; Chen S
    Clin Cancer Res; 2018 Nov; 24(21):5458-5470. PubMed ID: 30021909
    [No Abstract]   [Full Text] [Related]  

  • 19. Arachidonic acid induces Fas and FasL upregulation in human leukemia U937 cells via Ca2+/ROS-mediated suppression of ERK/c-Fos pathway and activation of p38 MAPK/ATF-2 pathway.
    Liu WH; Chang LS
    Toxicol Lett; 2009 Dec; 191(2-3):140-8. PubMed ID: 19720122
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Interplay of Akt and ERK in Aβ Toxicity and Insulin-Mediated Protection in Primary Hippocampal Cell Culture.
    Ghasemi R; Moosavi M; Zarifkar A; Rastegar K; Maghsoudi N
    J Mol Neurosci; 2015 Nov; 57(3):325-34. PubMed ID: 26266487
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.