BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

144 related articles for article (PubMed ID: 27757966)

  • 1. P-gp activity and inhibition in the different regions of human intestine ex vivo.
    Li M; de Graaf IA; de Jager MH; Groothuis GM
    Biopharm Drug Dispos; 2017 Mar; 38(2):127-138. PubMed ID: 27757966
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rat precision-cut intestinal slices to study P-gp activity and the potency of its inhibitors ex vivo.
    Li M; de Graaf IA; de Jager MH; Groothuis GM
    Toxicol In Vitro; 2015 Aug; 29(5):1070-8. PubMed ID: 25917215
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The consequence of regional gradients of P-gp and CYP3A4 for drug-drug interactions by P-gp inhibitors and the P-gp/CYP3A4 interplay in the human intestine ex vivo.
    Li M; de Graaf IA; van de Steeg E; de Jager MH; Groothuis GM
    Toxicol In Vitro; 2017 Apr; 40():26-33. PubMed ID: 27939799
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Consequence of Drug-Drug Interactions Influencing the Interplay between P-Glycoprotein and Cytochrome P450 3a: An Ex Vivo Study with Rat Precision-Cut Intestinal Slices.
    Li M; de Graaf IA; Siissalo S; de Jager MH; van Dam A; Groothuis GM
    Drug Metab Dispos; 2016 May; 44(5):683-91. PubMed ID: 26932816
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transport of rhodamine 123, a P-glycoprotein substrate, across rat intestine and Caco-2 cell monolayers in the presence of cytochrome P-450 3A-related compounds.
    Yumoto R; Murakami T; Nakamoto Y; Hasegawa R; Nagai J; Takano M
    J Pharmacol Exp Ther; 1999 Apr; 289(1):149-55. PubMed ID: 10086998
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Multiple efflux pumps are involved in the transepithelial transport of colchicine: combined effect of p-glycoprotein and multidrug resistance-associated protein 2 leads to decreased intestinal absorption throughout the entire small intestine.
    Dahan A; Sabit H; Amidon GL
    Drug Metab Dispos; 2009 Oct; 37(10):2028-36. PubMed ID: 19589874
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regional difference in P-glycoprotein function in rat intestine.
    Iida A; Tomita M; Hayashi M
    Drug Metab Pharmacokinet; 2005 Apr; 20(2):100-6. PubMed ID: 15855720
    [TBL] [Abstract][Full Text] [Related]  

  • 8. pH-dependent functional activity of P-glycoprotein in limiting intestinal absorption of protic drugs: kinetic analysis of quinidine efflux in situ.
    Varma MV; Panchagnula R
    J Pharm Sci; 2005 Dec; 94(12):2632-43. PubMed ID: 16258992
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [Effect of Tween-80 on the permeability of rhodamine 123, a P-gp substrate across rat intestinal membranes in vitro].
    Li GF; Tan YF; Guo D; Wang L
    Nan Fang Yi Ke Da Xue Xue Bao; 2008 Apr; 28(4):579-81. PubMed ID: 18495595
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Circadian variations in exsorptive transport: in situ intestinal perfusion data and in vivo relevance.
    Okyar A; Dressler C; Hanafy A; Baktir G; Lemmer B; Spahn-Langguth H
    Chronobiol Int; 2012 May; 29(4):443-53. PubMed ID: 22489638
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Prediction of in vivo intestinal absorption enhancement on P-glycoprotein inhibition, from rat in situ permeability.
    Varma MV; Panchagnula R
    J Pharm Sci; 2005 Aug; 94(8):1694-704. PubMed ID: 15986467
    [TBL] [Abstract][Full Text] [Related]  

  • 12. P-glycoprotein expression in the gastrointestinal tract of male and female rats is influenced differently by food.
    Dou L; Mai Y; Madla CM; Orlu M; Basit AW
    Eur J Pharm Sci; 2018 Oct; 123():569-575. PubMed ID: 30118850
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Acetaminophen inhibits intestinal p-glycoprotein transport activity.
    Novak A; Carpini GD; Ruiz ML; Luquita MG; Rubio MC; Mottino AD; Ghanem CI
    J Pharm Sci; 2013 Oct; 102(10):3830-7. PubMed ID: 23897240
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Gender-related differences on P-glycoprotein-mediated drug intestinal transport in rats.
    Mariana B; Adrián L; Guillermo V; Juan S; Laura M; Carlos L
    J Pharm Pharmacol; 2011 May; 63(5):619-26. PubMed ID: 21492163
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Segmental dependent transport of low permeability compounds along the small intestine due to P-glycoprotein: the role of efflux transport in the oral absorption of BCS class III drugs.
    Dahan A; Amidon GL
    Mol Pharm; 2009; 6(1):19-28. PubMed ID: 19248230
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In situ kinetic modelling of intestinal efflux in rats: functional characterization of segmental differences and correlation with in vitro results.
    González-Alvarez I; Fernández-Teruel C; Casabó-Alós VG; Garrigues TM; Polli JE; Ruiz-García A; Bermejo M
    Biopharm Drug Dispos; 2007 Jul; 28(5):229-39. PubMed ID: 17410527
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Permeability dominates in vivo intestinal absorption of P-gp substrate with high solubility and high permeability.
    Cao X; Yu LX; Barbaciru C; Landowski CP; Shin HC; Gibbs S; Miller HA; Amidon GL; Sun D
    Mol Pharm; 2005; 2(4):329-40. PubMed ID: 16053336
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Scaling of in vitro membrane permeability to predict P-glycoprotein-mediated drug absorption in vivo.
    Shirasaka Y; Masaoka Y; Kataoka M; Sakuma S; Yamashita S
    Drug Metab Dispos; 2008 May; 36(5):916-22. PubMed ID: 18276834
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Measurement of Rhodamine 123 in Three-Dimensional Organoids: A Novel Model for P-Glycoprotein Inhibitor Screening.
    Zhang Y; Zeng Z; Zhao J; Li D; Liu M; Wang X
    Basic Clin Pharmacol Toxicol; 2016 Oct; 119(4):349-52. PubMed ID: 27060462
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Improvement of intestinal absorption of P-glycoprotein substrate by D-tartaric acid.
    Iida A; Tomita M; Idota Y; Takizawa Y; Hayashi M
    Drug Metab Pharmacokinet; 2006 Oct; 21(5):424-8. PubMed ID: 17072096
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.