175 related articles for article (PubMed ID: 27758804)
1. Tramadol metabolism to O-desmethyl tramadol (M1) and N-desmethyl tramadol (M2) by dog liver microsomes: Species comparison and identification of responsible canine cytochrome P-450s (CYPs).
Perez Jimenez TE; Mealey KL; Grubb TL; Greene SA; Court MH
Drug Metab Dispos; 2016 Dec; 44(12):1963-1972. PubMed ID: 27758804
[TBL] [Abstract][Full Text] [Related]
2. Identification of canine cytochrome P-450s (CYPs) metabolizing the tramadol (+)-M1 and (+)-M2 metabolites to the tramadol (+)-M5 metabolite in dog liver microsomes.
Perez Jimenez TE; Mealey KL; Schnider D; Grubb TL; Greene SA; Court MH
J Vet Pharmacol Ther; 2018 Dec; 41(6):815-824. PubMed ID: 30113702
[TBL] [Abstract][Full Text] [Related]
3. Identification of cytochrome P-450 isoforms responsible for cis-tramadol metabolism in human liver microsomes.
Subrahmanyam V; Renwick AB; Walters DG; Young PJ; Price RJ; Tonelli AP; Lake BG
Drug Metab Dispos; 2001 Aug; 29(8):1146-55. PubMed ID: 11454734
[TBL] [Abstract][Full Text] [Related]
4. Correction to "Tramadol Metabolism to O-Desmethyl Tramadol (M1) and N-Desmethyl Tramadol (M2) by Dog Liver Microsomes: Species Comparison and Identification of Responsible Canine Cytochrome P450s".
Drug Metab Dispos; 2017 Jul; 45(7):706. PubMed ID: 28559373
[No Abstract] [Full Text] [Related]
5. Intrinsic clearance rate of O-desmethyltramadol (M1) by glucuronide conjugation and phase I metabolism by feline, canine and common brush-tailed possum microsomes.
Izes AM; Kimble B; Govendir M
Xenobiotica; 2020 Jul; 50(7):776-782. PubMed ID: 31755346
[TBL] [Abstract][Full Text] [Related]
6. Cannabidiol and cannabidiolic acid: Preliminary in vitro evaluation of metabolism and drug-drug interactions involving canine cytochrome P-450, UDP-glucuronosyltransferase, and P-glycoprotein.
Court MH; Mealey KL; Burke NS; Jimenez TP; Zhu Z; Wakshlag JJ
J Vet Pharmacol Ther; 2024 Jan; 47(1):1-13. PubMed ID: 37469115
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of CYP2D6-mediated tramadol O-demethylation in methadone but not buprenorphine maintenance patients.
Coller JK; Michalakas JR; James HM; Farquharson AL; Colvill J; White JM; Somogyi AA
Br J Clin Pharmacol; 2012 Nov; 74(5):835-41. PubMed ID: 22369095
[TBL] [Abstract][Full Text] [Related]
8. Oral Coadministration of Fluconazole with Tramadol Markedly Increases Plasma and Urine Concentrations of Tramadol and the
Perez Jimenez TE; Kukanich B; Joo H; Mealey KL; Grubb TL; Greene SA; Court MH
Drug Metab Dispos; 2019 Jan; 47(1):15-25. PubMed ID: 30366901
[TBL] [Abstract][Full Text] [Related]
9. Absolute Quantitation of Drug-Metabolizing Cytochrome P450 Enzymes and Accessory Proteins in Dog Liver Microsomes Using Label-Free Standard-Free Analysis Reveals Interbreed Variability.
Martinez SE; Shi J; Zhu HJ; Perez Jimenez TE; Zhu Z; Court MH
Drug Metab Dispos; 2019 Nov; 47(11):1314-1324. PubMed ID: 31427433
[TBL] [Abstract][Full Text] [Related]
10. In vitro metabolism of l-corydalmine, a potent analgesic drug, in human, cynomolgus monkey, beagle dog, rat and mouse liver microsomes.
Tang X; Di X; Zhong Z; Xie Q; Chen Y; Wang F; Ling Z; Xu P; Zhao K; Wang Z; Liu L; Liu X
J Pharm Biomed Anal; 2016 Sep; 128():98-105. PubMed ID: 27239758
[TBL] [Abstract][Full Text] [Related]
11. Reaction phenotyping of vinblastine metabolism in dogs.
Achanta S; Maxwell LK
Vet Comp Oncol; 2016 Jun; 14(2):161-9. PubMed ID: 24502418
[TBL] [Abstract][Full Text] [Related]
12. Pharmacogenomics of poor drug metabolism in greyhounds: Canine P450 oxidoreductase genetic variation, breed heterogeneity, and functional characterization.
Martinez SE; Pandey AV; Perez Jimenez TE; Zhu Z; Court MH
PLoS One; 2024; 19(2):e0297191. PubMed ID: 38300925
[TBL] [Abstract][Full Text] [Related]
13. Biotransformation of 6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes.
Yao HT; Wu YS; Chang YW; Hsieh HP; Chen WC; Lan SJ; Chen CT; Chao YS; Chang L; Sun HY; Yeh TK
Drug Metab Dispos; 2007 Jul; 35(7):1042-9. PubMed ID: 17403915
[TBL] [Abstract][Full Text] [Related]
14. Cytochrome P450 reaction phenotyping of itraconazole hydroxylation in the dog.
Tonero ME; Li Z; Reinhart JM
J Vet Pharmacol Ther; 2022 May; 45(3):255-264. PubMed ID: 35389533
[TBL] [Abstract][Full Text] [Related]
15. Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A.
Niwa T; Shiraga T; Mitani Y; Terakawa M; Tokuma Y; Kagayama A
Drug Metab Dispos; 2000 Sep; 28(9):1128-34. PubMed ID: 10950860
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of cytochrome P450 enzymes involved in ketamine metabolism by use of liver microsomes and specific cytochrome P450 enzymes from horses, dogs, and humans.
Mössner LD; Schmitz A; Theurillat R; Thormann W; Mevissen M
Am J Vet Res; 2011 Nov; 72(11):1505-13. PubMed ID: 22023129
[TBL] [Abstract][Full Text] [Related]
17. Cytochrome P450-mediated hepatic metabolism of new fluorescent substrates in cats and dogs.
van Beusekom CD; Schipper L; Fink-Gremmels J
J Vet Pharmacol Ther; 2010 Dec; 33(6):519-27. PubMed ID: 21062303
[TBL] [Abstract][Full Text] [Related]
18. Association of cytochrome P450 2D15 (CYP2D15) nonsynonymous polymorphisms and exon 3 deleted RNA splice variant with CYP2D15 protein content and enzyme function in dog liver microsomes.
Jimenez TP; Zhu Z; Court MH
J Vet Pharmacol Ther; 2023 Mar; 46(2):77-90. PubMed ID: 36691326
[TBL] [Abstract][Full Text] [Related]
19. Selective inhibition of dog hepatic CYP2B11 and CYP3A12.
Lu P; Singh SB; Carr BA; Fang Y; Xiang CD; Rushmore TH; Rodrigues AD; Shou M
J Pharmacol Exp Ther; 2005 May; 313(2):518-28. PubMed ID: 15677349
[TBL] [Abstract][Full Text] [Related]
20. Substrate specificity and kinetic properties of seven heterologously expressed dog cytochromes p450.
Shou M; Norcross R; Sandig G; Lu P; Li Y; Lin Y; Mei Q; Rodrigues AD; Rushmore TH
Drug Metab Dispos; 2003 Sep; 31(9):1161-9. PubMed ID: 12920172
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]