236 related articles for article (PubMed ID: 27758869)
1. Hyaluronan Production Regulates Metabolic and Cancer Stem-like Properties of Breast Cancer Cells via Hexosamine Biosynthetic Pathway-coupled HIF-1 Signaling.
Chanmee T; Ontong P; Izumikawa T; Higashide M; Mochizuki N; Chokchaitaweesuk C; Khansai M; Nakajima K; Kakizaki I; Kongtawelert P; Taniguchi N; Itano N
J Biol Chem; 2016 Nov; 291(46):24105-24120. PubMed ID: 27758869
[TBL] [Abstract][Full Text] [Related]
2. Enhanced hexosamine metabolism drives metabolic and signaling networks involving hyaluronan production and O-GlcNAcylation to exacerbate breast cancer.
Chokchaitaweesuk C; Kobayashi T; Izumikawa T; Itano N
Cell Death Dis; 2019 Oct; 10(11):803. PubMed ID: 31645543
[TBL] [Abstract][Full Text] [Related]
3. Excessive hyaluronan production promotes acquisition of cancer stem cell signatures through the coordinated regulation of Twist and the transforming growth factor β (TGF-β)-Snail signaling axis.
Chanmee T; Ontong P; Mochizuki N; Kongtawelert P; Konno K; Itano N
J Biol Chem; 2014 Sep; 289(38):26038-26056. PubMed ID: 25077968
[TBL] [Abstract][Full Text] [Related]
4. mTORC2 Responds to Glutamine Catabolite Levels to Modulate the Hexosamine Biosynthesis Enzyme GFAT1.
Moloughney JG; Kim PK; Vega-Cotto NM; Wu CC; Zhang S; Adlam M; Lynch T; Chou PC; Rabinowitz JD; Werlen G; Jacinto E
Mol Cell; 2016 Sep; 63(5):811-26. PubMed ID: 27570073
[TBL] [Abstract][Full Text] [Related]
5. mTORC2 modulates the amplitude and duration of GFAT1 Ser-243 phosphorylation to maintain flux through the hexosamine pathway during starvation.
Moloughney JG; Vega-Cotto NM; Liu S; Patel C; Kim PK; Wu CC; Albaciete D; Magaway C; Chang A; Rajput S; Su X; Werlen G; Jacinto E
J Biol Chem; 2018 Oct; 293(42):16464-16478. PubMed ID: 30201609
[TBL] [Abstract][Full Text] [Related]
6. Hexosamine biosynthesis in keratinocytes: roles of GFAT and GNPDA enzymes in the maintenance of UDP-GlcNAc content and hyaluronan synthesis.
Oikari S; Makkonen K; Deen AJ; Tyni I; Kärnä R; Tammi RH; Tammi MI
Glycobiology; 2016 Jul; 26(7):710-22. PubMed ID: 26887390
[TBL] [Abstract][Full Text] [Related]
7. Regulatory role of hexosamine biosynthetic pathway on hepatic cancer stem cell marker CD133 under low glucose conditions.
Lin SH; Liu T; Ming X; Tang Z; Fu L; Schmitt-Kopplin P; Kanawati B; Guan XY; Cai Z
Sci Rep; 2016 Feb; 6():21184. PubMed ID: 26878908
[TBL] [Abstract][Full Text] [Related]
8. Nutrient shortage triggers the hexosamine biosynthetic pathway via the GCN2-ATF4 signalling pathway.
Chaveroux C; Sarcinelli C; Barbet V; Belfeki S; Barthelaix A; Ferraro-Peyret C; Lebecque S; Renno T; Bruhat A; Fafournoux P; Manié SN
Sci Rep; 2016 Jun; 6():27278. PubMed ID: 27255611
[TBL] [Abstract][Full Text] [Related]
9. Hyaluronic acid fuels pancreatic cancer cell growth.
Kim PK; Halbrook CJ; Kerk SA; Radyk M; Wisner S; Kremer DM; Sajjakulnukit P; Andren A; Hou SW; Trivedi A; Thurston G; Anand A; Yan L; Salamanca-Cardona L; Welling SD; Zhang L; Pratt MR; Keshari KR; Ying H; Lyssiotis CA
Elife; 2021 Dec; 10():. PubMed ID: 34951587
[TBL] [Abstract][Full Text] [Related]
10. HIF-1α induces the epithelial-mesenchymal transition in gastric cancer stem cells through the Snail pathway.
Yang SW; Zhang ZG; Hao YX; Zhao YL; Qian F; Shi Y; Li PA; Liu CY; Yu PW
Oncotarget; 2017 Feb; 8(6):9535-9545. PubMed ID: 28076840
[TBL] [Abstract][Full Text] [Related]
11. The hexosamine biosynthetic pathway induces gene promoter activity of acetyl-CoA carboxylase beta.
Imbriolo J; Mapanga RF; Essop MF
Biochem Biophys Res Commun; 2014 Sep; 452(3):734-9. PubMed ID: 25195817
[TBL] [Abstract][Full Text] [Related]
12. Contrasting hypoxic effects on breast cancer stem cell hierarchy is dependent on ER-α status.
Harrison H; Rogerson L; Gregson HJ; Brennan KR; Clarke RB; Landberg G
Cancer Res; 2013 Feb; 73(4):1420-33. PubMed ID: 23248117
[TBL] [Abstract][Full Text] [Related]
13. Osteopontin promotes a cancer stem cell-like phenotype in hepatocellular carcinoma cells via an integrin-NF-κB-HIF-1α pathway.
Cao L; Fan X; Jing W; Liang Y; Chen R; Liu Y; Zhu M; Jia R; Wang H; Zhang X; Zhang Y; Zhou X; Zhao J; Guo Y
Oncotarget; 2015 Mar; 6(9):6627-40. PubMed ID: 25749383
[TBL] [Abstract][Full Text] [Related]
14. Impairment of HIF-1α-mediated metabolic adaption by NRF2-silencing in breast cancer cells.
Lee S; Hallis SP; Jung KA; Ryu D; Kwak MK
Redox Biol; 2019 Jun; 24():101210. PubMed ID: 31078780
[TBL] [Abstract][Full Text] [Related]
15. GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis.
Zibrova D; Vandermoere F; Göransson O; Peggie M; Mariño KV; Knierim A; Spengler K; Weigert C; Viollet B; Morrice NA; Sakamoto K; Heller R
Biochem J; 2017 Mar; 474(6):983-1001. PubMed ID: 28008135
[TBL] [Abstract][Full Text] [Related]
16. CRLX101, an investigational camptothecin-containing nanoparticle-drug conjugate, targets cancer stem cells and impedes resistance to antiangiogenic therapy in mouse models of breast cancer.
Conley SJ; Baker TL; Burnett JP; Theisen RL; Lazarus D; Peters CG; Clouthier SG; Eliasof S; Wicha MS
Breast Cancer Res Treat; 2015 Apr; 150(3):559-67. PubMed ID: 25833208
[TBL] [Abstract][Full Text] [Related]
17. HIF-1-alpha links mitochondrial perturbation to the dynamic acquisition of breast cancer tumorigenicity.
Kuo CY; Cheng CT; Hou P; Lin YP; Ma H; Chung Y; Chi K; Chen Y; Li W; Kung HJ; Ann DK
Oncotarget; 2016 Jun; 7(23):34052-69. PubMed ID: 27058900
[TBL] [Abstract][Full Text] [Related]
18. Cardiomyocyte protein O-GlcNAcylation is regulated by GFAT1 not GFAT2.
Nabeebaccus AA; Verma S; Zoccarato A; Emanuelli G; Santos CX; Streckfuss-Bömeke K; Shah AM
Biochem Biophys Res Commun; 2021 Dec; 583():121-127. PubMed ID: 34735873
[TBL] [Abstract][Full Text] [Related]
19. Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1alpha.
Soeda A; Park M; Lee D; Mintz A; Androutsellis-Theotokis A; McKay RD; Engh J; Iwama T; Kunisada T; Kassam AB; Pollack IF; Park DM
Oncogene; 2009 Nov; 28(45):3949-59. PubMed ID: 19718046
[TBL] [Abstract][Full Text] [Related]
20. ITGA6 is directly regulated by hypoxia-inducible factors and enriches for cancer stem cell activity and invasion in metastatic breast cancer models.
Brooks DL; Schwab LP; Krutilina R; Parke DN; Sethuraman A; Hoogewijs D; Schörg A; Gotwald L; Fan M; Wenger RH; Seagroves TN
Mol Cancer; 2016 Mar; 15():26. PubMed ID: 27001172
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
