These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

336 related articles for article (PubMed ID: 27760837)

  • 1. 6α-Acetoxyanopterine: A Novel Structure Class of Mitotic Inhibitor Disrupting Microtubule Dynamics in Prostate Cancer Cells.
    Levrier C; Sadowski MC; Rockstroh A; Gabrielli B; Kavallaris M; Lehman M; Davis RA; Nelson CC
    Mol Cancer Ther; 2017 Jan; 16(1):3-15. PubMed ID: 27760837
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of thalicthuberine as a novel antimitotic agent from nature that disrupts microtubule dynamics and induces apoptosis in prostate cancer cells.
    Levrier C; Rockstroh A; Gabrielli B; Kavallaris M; Lehman M; Davis RA; Sadowski MC; Nelson CC
    Cell Cycle; 2018; 17(5):652-668. PubMed ID: 28749250
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Indirubin, a bis-indole alkaloid binds to tubulin and exhibits antimitotic activity against HeLa cells in synergism with vinblastine.
    Mohan L; Raghav D; Ashraf SM; Sebastian J; Rathinasamy K
    Biomed Pharmacother; 2018 Sep; 105():506-517. PubMed ID: 29883946
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tubulin-based antimitotic mechanism of E7974, a novel analogue of the marine sponge natural product hemiasterlin.
    Kuznetsov G; TenDyke K; Towle MJ; Cheng H; Liu J; Marsh JP; Schiller SE; Spyvee MR; Yang H; Seletsky BM; Shaffer CJ; Marceau V; Yao Y; Suh EM; Campagna S; Fang FG; Kowalczyk JJ; Littlefield BA
    Mol Cancer Ther; 2009 Oct; 8(10):2852-60. PubMed ID: 19825803
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 2-Methoxyestradiol suppresses microtubule dynamics and arrests mitosis without depolymerizing microtubules.
    Kamath K; Okouneva T; Larson G; Panda D; Wilson L; Jordan MA
    Mol Cancer Ther; 2006 Sep; 5(9):2225-33. PubMed ID: 16985056
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitosis.
    Jordan MA; Thrower D; Wilson L
    J Cell Sci; 1992 Jul; 102 ( Pt 3)():401-16. PubMed ID: 1506423
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Griseofulvin stabilizes microtubule dynamics, activates p53 and inhibits the proliferation of MCF-7 cells synergistically with vinblastine.
    Rathinasamy K; Jindal B; Asthana J; Singh P; Balaji PV; Panda D
    BMC Cancer; 2010 May; 10():213. PubMed ID: 20482847
    [TBL] [Abstract][Full Text] [Related]  

  • 8. LG308, a Novel Synthetic Compound with Antimicrotubule Activity in Prostate Cancer Cells, Exerts Effective Antitumor Activity.
    Qin M; Peng S; Liu N; Hu M; He Y; Li G; Chen H; He Y; Chen A; Wang X; Liu M; Chen Y; Yi Z
    J Pharmacol Exp Ther; 2015 Dec; 355(3):473-83. PubMed ID: 26377911
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The primary antimitotic mechanism of action of the synthetic halichondrin E7389 is suppression of microtubule growth.
    Jordan MA; Kamath K; Manna T; Okouneva T; Miller HP; Davis C; Littlefield BA; Wilson L
    Mol Cancer Ther; 2005 Jul; 4(7):1086-95. PubMed ID: 16020666
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The novel microtubule-destabilizing drug BAL27862 binds to the colchicine site of tubulin with distinct effects on microtubule organization.
    Prota AE; Danel F; Bachmann F; Bargsten K; Buey RM; Pohlmann J; Reinelt S; Lane H; Steinmetz MO
    J Mol Biol; 2014 Apr; 426(8):1848-60. PubMed ID: 24530796
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Antiproliferative Activity of Crocin Involves Targeting of Microtubules in Breast Cancer Cells.
    Hire RR; Srivastava S; Davis MB; Kumar Konreddy A; Panda D
    Sci Rep; 2017 Mar; 7():44984. PubMed ID: 28337976
    [TBL] [Abstract][Full Text] [Related]  

  • 12. G-1 Inhibits Breast Cancer Cell Growth via Targeting Colchicine-Binding Site of Tubulin to Interfere with Microtubule Assembly.
    Lv X; He C; Huang C; Hua G; Wang Z; Remmenga SW; Rodabough KJ; Karpf AR; Dong J; Davis JS; Wang C
    Mol Cancer Ther; 2017 Jun; 16(6):1080-1091. PubMed ID: 28258163
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mitotic cell death induction by targeting the mitotic spindle with tubulin-inhibitory indole derivative molecules.
    Di Cesare E; Verrico A; Miele A; Giubettini M; Rovella P; Coluccia A; Famiglini V; La Regina G; Cundari E; Silvestri R; Lavia P
    Oncotarget; 2017 Mar; 8(12):19738-19759. PubMed ID: 28160569
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Microtubule dynamics, mitotic arrest, and apoptosis: drug-induced differential effects of betaIII-tubulin.
    Gan PP; McCarroll JA; Po'uha ST; Kamath K; Jordan MA; Kavallaris M
    Mol Cancer Ther; 2010 May; 9(5):1339-48. PubMed ID: 20442307
    [TBL] [Abstract][Full Text] [Related]  

  • 15. NMK-BH2, a novel microtubule-depolymerising bis (indolyl)-hydrazide-hydrazone, induces apoptotic and autophagic cell death in cervical cancer cells by binding to tubulin at colchicine - site.
    Das Mukherjee D; Kumar NM; Tantak MP; Datta S; Ghosh Dastidar D; Kumar D; Chakrabarti G
    Biochim Biophys Acta Mol Cell Res; 2020 Oct; 1867(10):118762. PubMed ID: 32502617
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NMK-TD-100, a novel microtubule modulating agent, blocks mitosis and induces apoptosis in HeLa cells by binding to tubulin.
    Bhattacharya S; Kumar NM; Ganguli A; Tantak MP; Kumar D; Chakrabarti G
    PLoS One; 2013; 8(10):e76286. PubMed ID: 24116100
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An antitubulin agent BCFMT inhibits proliferation of cancer cells and induces cell death by inhibiting microtubule dynamics.
    Rai A; Surolia A; Panda D
    PLoS One; 2012; 7(8):e44311. PubMed ID: 22952952
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A new class of cytotoxic agents targets tubulin and disrupts microtubule dynamics.
    Al-Hamashi AA; Koranne R; Dlamini S; Alqahtani A; Karaj E; Rashid MS; Knoff JR; Dunworth M; Pflum MKH; Casero RA; Perera L; Taylor WR; Tillekeratne LMV
    Bioorg Chem; 2021 Nov; 116():105297. PubMed ID: 34509798
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Selective Inhibition of Spindle Microtubules by a Tubulin-Binding Quinazoline Derivative.
    Sawada JI; Ishii H; Matsuno K; Sato M; Suzuki Y; Asai A
    Mol Pharmacol; 2019 Nov; 96(5):609-618. PubMed ID: 31471455
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MT7, a novel compound from a combinatorial library, arrests mitosis via inhibiting the polymerization of microtubules.
    Zhang Z; Meng T; He J; Li M; Tong LJ; Xiong B; Lin L; Shen J; Miao ZH; Ding J
    Invest New Drugs; 2010 Dec; 28(6):715-28. PubMed ID: 19705064
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.