381 related articles for article (PubMed ID: 27764247)
1. SIRT1-PGC1α-NFκB Pathway of Oxidative and Inflammatory Stress during Trypanosoma cruzi Infection: Benefits of SIRT1-Targeted Therapy in Improving Heart Function in Chagas Disease.
Wan X; Wen JJ; Koo SJ; Liang LY; Garg NJ
PLoS Pathog; 2016 Oct; 12(10):e1005954. PubMed ID: 27764247
[TBL] [Abstract][Full Text] [Related]
2. Origin of Monocytes/Macrophages Contributing to Chronic Inflammation in Chagas Disease: SIRT1 Inhibition of FAK-NFκB-Dependent Proliferation and Proinflammatory Activation of Macrophages.
Wan X; Chowdhury IH; Jie Z; Choudhuri S; Garg NJ
Cells; 2019 Dec; 9(1):. PubMed ID: 31905606
[TBL] [Abstract][Full Text] [Related]
3. Resveratrol alleviates diabetic cardiomyopathy in rats by improving mitochondrial function through PGC-1α deacetylation.
Fang WJ; Wang CJ; He Y; Zhou YL; Peng XD; Liu SK
Acta Pharmacol Sin; 2018 Jan; 39(1):59-73. PubMed ID: 28770830
[TBL] [Abstract][Full Text] [Related]
4. Defects of mtDNA replication impaired mitochondrial biogenesis during Trypanosoma cruzi infection in human cardiomyocytes and chagasic patients: the role of Nrf1/2 and antioxidant response.
Wan X; Gupta S; Zago MP; Davidson MM; Dousset P; Amoroso A; Garg NJ
J Am Heart Assoc; 2012 Dec; 1(6):e003855. PubMed ID: 23316324
[TBL] [Abstract][Full Text] [Related]
5. PARP1 depletion improves mitochondrial and heart function in Chagas disease: Effects on POLG dependent mtDNA maintenance.
Wen JJ; Yin YW; Garg NJ
PLoS Pathog; 2018 May; 14(5):e1007065. PubMed ID: 29851986
[TBL] [Abstract][Full Text] [Related]
6. Inhibition of NFE2L2-Antioxidant Response Element Pathway by Mitochondrial Reactive Oxygen Species Contributes to Development of Cardiomyopathy and Left Ventricular Dysfunction in Chagas Disease.
Wen JJ; Porter C; Garg NJ
Antioxid Redox Signal; 2017 Sep; 27(9):550-566. PubMed ID: 28132522
[TBL] [Abstract][Full Text] [Related]
7. Therapeutic Efficacy of a Subunit Vaccine in Controlling Chronic Trypanosoma cruzi Infection and Chagas Disease Is Enhanced by Glutathione Peroxidase Over-Expression.
Gupta S; Smith C; Auclair S; Delgadillo Ade J; Garg NJ
PLoS One; 2015; 10(6):e0130562. PubMed ID: 26075398
[TBL] [Abstract][Full Text] [Related]
8. Manganese superoxide dismutase deficiency exacerbates the mitochondrial ROS production and oxidative damage in Chagas disease.
Wen JJ; Garg NJ
PLoS Negl Trop Dis; 2018 Jul; 12(7):e0006687. PubMed ID: 30044789
[TBL] [Abstract][Full Text] [Related]
9. PGC1α activation by pterostilbene ameliorates acute doxorubicin cardiotoxicity by reducing oxidative stress via enhancing AMPK and SIRT1 cascades.
Liu D; Ma Z; Xu L; Zhang X; Qiao S; Yuan J
Aging (Albany NY); 2019 Nov; 11(22):10061-10073. PubMed ID: 31733141
[TBL] [Abstract][Full Text] [Related]
10. Mitochondrial aldehyde dehydrogenase 2 accentuates aging-induced cardiac remodeling and contractile dysfunction: role of AMPK, Sirt1, and mitochondrial function.
Zhang Y; Mi SL; Hu N; Doser TA; Sun A; Ge J; Ren J
Free Radic Biol Med; 2014 Jun; 71():208-220. PubMed ID: 24675227
[TBL] [Abstract][Full Text] [Related]
11. A SIRT1 agonist reduces cognitive decline in type 2 diabetic rats through antioxidative and anti‑inflammatory mechanisms.
Wang F; Shang Y; Zhang R; Gao X; Zeng Q
Mol Med Rep; 2019 Feb; 19(2):1040-1048. PubMed ID: 30483738
[TBL] [Abstract][Full Text] [Related]
12. Phenyl-alpha-tert-butyl-nitrone and benzonidazole treatment controlled the mitochondrial oxidative stress and evolution of cardiomyopathy in chronic chagasic Rats.
Wen JJ; Gupta S; Guan Z; Dhiman M; Condon D; Lui C; Garg NJ
J Am Coll Cardiol; 2010 Jun; 55(22):2499-508. PubMed ID: 20510218
[TBL] [Abstract][Full Text] [Related]
13. Chemotherapeutic efficacy of phosphodiesterase inhibitors in chagasic cardiomyopathy.
Wen JJ; Wan X; Thacker J; Garg NJ
JACC Basic Transl Sci; 2016 Jun; 1(4):235-250. PubMed ID: 27747306
[TBL] [Abstract][Full Text] [Related]
14. Sirtuin 1 activator SRT1720 suppresses inflammation in an ovalbumin-induced mouse model of asthma.
Ichikawa T; Hayashi R; Suzuki K; Imanishi S; Kambara K; Okazawa S; Inomata M; Yamada T; Yamazaki Y; Koshimizu Y; Miwa T; Matsui S; Usui I; Urakaze M; Matsuya Y; Sasahara M; Tobe K
Respirology; 2013 Feb; 18(2):332-9. PubMed ID: 23062010
[TBL] [Abstract][Full Text] [Related]
15. Pharmacological upregulation of PGC1α in oligodendrocytes: implications for Huntington's Disease.
Xiang Z; Krainc D
J Huntingtons Dis; 2013; 2(1):101-5. PubMed ID: 25063433
[TBL] [Abstract][Full Text] [Related]
16. The Effects of Resveratrol on Inflammation and Oxidative Stress in a Rat Model of Chronic Obstructive Pulmonary Disease.
Wang XL; Li T; Li JH; Miao SY; Xiao XZ
Molecules; 2017 Sep; 22(9):. PubMed ID: 28895883
[TBL] [Abstract][Full Text] [Related]
17. Resveratrol Reverses Functional Chagas Heart Disease in Mice.
Vilar-Pereira G; Carneiro VC; Mata-Santos H; Vicentino AR; Ramos IP; Giarola NL; Feijó DF; Meyer-Fernandes JR; Paula-Neto HA; Medei E; Bozza MT; Lannes-Vieira J; Paiva CN
PLoS Pathog; 2016 Oct; 12(10):e1005947. PubMed ID: 27788262
[TBL] [Abstract][Full Text] [Related]
18. Dual peroxisome-proliferator-activated-receptor-α/γ activation inhibits SIRT1-PGC1α axis and causes cardiac dysfunction.
Kalliora C; Kyriazis ID; Oka SI; Lieu MJ; Yue Y; Area-Gomez E; Pol CJ; Tian Y; Mizushima W; Chin A; Scerbo D; Schulze PC; Civelek M; Sadoshima J; Madesh M; Goldberg IJ; Drosatos K
JCI Insight; 2019 Aug; 5(17):. PubMed ID: 31393858
[TBL] [Abstract][Full Text] [Related]
19. Regulation of diabetic cardiomyopathy by caloric restriction is mediated by intracellular signaling pathways involving 'SIRT1 and PGC-1α'.
Waldman M; Cohen K; Yadin D; Nudelman V; Gorfil D; Laniado-Schwartzman M; Kornwoski R; Aravot D; Abraham NG; Arad M; Hochhauser E
Cardiovasc Diabetol; 2018 Aug; 17(1):111. PubMed ID: 30071860
[TBL] [Abstract][Full Text] [Related]
20. Sirtuin 1 activation stimulates mitochondrial biogenesis and attenuates renal injury after ischemia-reperfusion.
Khader A; Yang WL; Kuncewitch M; Jacob A; Prince JM; Asirvatham JR; Nicastro J; Coppa GF; Wang P
Transplantation; 2014 Jul; 98(2):148-56. PubMed ID: 24918615
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]