343 related articles for article (PubMed ID: 27765358)
1. Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication.
Esposito F; Carli I; Del Vecchio C; Xu L; Corona A; Grandi N; Piano D; Maccioni E; Distinto S; Parolin C; Tramontano E
Phytomedicine; 2016 Nov; 23(12):1383-1391. PubMed ID: 27765358
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 reverse transcriptase-associated RNase H and RDDP functions.
Corona A; Onnis V; Deplano A; Bianco G; Demurtas M; Distinto S; Cheng YC; Alcaro S; Esposito F; Tramontano E
Pathog Dis; 2017 Aug; 75(6):. PubMed ID: 28859311
[TBL] [Abstract][Full Text] [Related]
3. Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6.
Corona A; Meleddu R; Esposito F; Distinto S; Bianco G; Masaoka T; Maccioni E; Menéndez-Arias L; Alcaro S; Le Grice SF; Tramontano E
PLoS One; 2016; 11(1):e0147225. PubMed ID: 26800261
[TBL] [Abstract][Full Text] [Related]
4. 2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication.
Corona A; Onnis V; Del Vecchio C; Esposito F; Cheng YC; Tramontano E
Molecules; 2020 Mar; 25(6):. PubMed ID: 32183488
[TBL] [Abstract][Full Text] [Related]
5. Developing and Evaluating Inhibitors against the RNase H Active Site of HIV-1 Reverse Transcriptase.
Boyer PL; Smith SJ; Zhao XZ; Das K; Gruber K; Arnold E; Burke TR; Hughes SH
J Virol; 2018 Jul; 92(13):. PubMed ID: 29643235
[TBL] [Abstract][Full Text] [Related]
6. From the traditional Chinese medicine plant Schisandra chinensis new scaffolds effective on HIV-1 reverse transcriptase resistant to non-nucleoside inhibitors.
Xu L; Grandi N; Del Vecchio C; Mandas D; Corona A; Piano D; Esposito F; Parolin C; Tramontano E
J Microbiol; 2015 Apr; 53(4):288-93. PubMed ID: 25740376
[TBL] [Abstract][Full Text] [Related]
7. 6-[1-(4-Fluorophenyl)methyl-1H-pyrrol-2-yl)]-2,4-dioxo-5-hexenoic acid ethyl ester a novel diketo acid derivative which selectively inhibits the HIV-1 viral replication in cell culture and the ribonuclease H activity in vitro.
Tramontano E; Esposito F; Badas R; Di Santo R; Costi R; La Colla P
Antiviral Res; 2005 Feb; 65(2):117-24. PubMed ID: 15708638
[TBL] [Abstract][Full Text] [Related]
8. Uvaria angolensis as a promising source of inhibitors of HIV-1 RT-associated RNA-dependent DNA polymerase and RNase H functions.
Ngoutane Mfopa A; Corona A; Eloh K; Tramontano E; Frau A; Boyom FF; Caboni P; Tocco G
Nat Prod Res; 2018 Mar; 32(6):640-647. PubMed ID: 28540745
[TBL] [Abstract][Full Text] [Related]
9. New insights into the interaction between pyrrolyl diketoacids and HIV-1 integrase active site and comparison with RNase H.
Corona A; di Leva FS; Rigogliuso G; Pescatori L; Madia VN; Subra F; Delelis O; Esposito F; Cadeddu M; Costi R; Cosconati S; Novellino E; di Santo R; Tramontano E
Antiviral Res; 2016 Oct; 134():236-243. PubMed ID: 27659398
[TBL] [Abstract][Full Text] [Related]
10. 5-Hydroxypyrido[2,3-b]pyrazin-6(5H)-one derivatives as novel dual inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H and integrase.
Sun L; Gao P; Dong G; Zhang X; Cheng X; Ding X; Wang X; Daelemans D; De Clercq E; Pannecouque C; Menéndez-Arias L; Zhan P; Liu X
Eur J Med Chem; 2018 Jul; 155():714-724. PubMed ID: 29940462
[TBL] [Abstract][Full Text] [Related]
11. Structure-activity relationship of pyrrolyl diketo acid derivatives as dual inhibitors of HIV-1 integrase and reverse transcriptase ribonuclease H domain.
Cuzzucoli Crucitti G; Métifiot M; Pescatori L; Messore A; Madia VN; Pupo G; Saccoliti F; Scipione L; Tortorella S; Esposito F; Corona A; Cadeddu M; Marchand C; Pommier Y; Tramontano E; Costi R; Di Santo R
J Med Chem; 2015 Feb; 58(4):1915-28. PubMed ID: 25629256
[TBL] [Abstract][Full Text] [Related]
12. Prenylated phloroglucinols from Hypericum scruglii, an endemic species of Sardinia (Italy), as new dual HIV-1 inhibitors effective on HIV-1 replication.
Sanna C; Scognamiglio M; Fiorentino A; Corona A; Graziani V; Caredda A; Cortis P; Montisci M; Ceresola ER; Canducci F; Poli F; Tramontano E; Esposito F
PLoS One; 2018; 13(3):e0195168. PubMed ID: 29601601
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of the DNA polymerase and RNase H activities of HIV-1 reverse transcriptase and HIV-1 replication by Brasenia schreberi (Junsai) and Petasites japonicus (Fuki) components.
Hisayoshi T; Shinomura M; Yokokawa K; Kuze I; Konishi A; Kawaji K; Kodama EN; Hata K; Takahashi S; Nirasawa S; Sakuda S; Yasukawa K
J Nat Med; 2015 Jul; 69(3):432-40. PubMed ID: 25663480
[TBL] [Abstract][Full Text] [Related]
14. Evaluation of selected South African medicinal plants for inhibitory properties against human immunodeficiency virus type 1 reverse transcriptase and integrase.
Bessong PO; Obi CL; Andréola ML; Rojas LB; Pouységu L; Igumbor E; Meyer JJ; Quideau S; Litvak S
J Ethnopharmacol; 2005 May; 99(1):83-91. PubMed ID: 15848024
[TBL] [Abstract][Full Text] [Related]
15. Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases.
Esposito F; Kharlamova T; Distinto S; Zinzula L; Cheng YC; Dutschman G; Floris G; Markt P; Corona A; Tramontano E
FEBS J; 2011 May; 278(9):1444-57. PubMed ID: 21348941
[TBL] [Abstract][Full Text] [Related]
16. The P236L delavirdine-resistant human immunodeficiency virus type 1 mutant is replication defective and demonstrates alterations in both RNA 5'-end- and DNA 3'-end-directed RNase H activities.
Gerondelis P; Archer RH; Palaniappan C; Reichman RC; Fay PJ; Bambara RA; Demeter LM
J Virol; 1999 Jul; 73(7):5803-13. PubMed ID: 10364332
[TBL] [Abstract][Full Text] [Related]
17. Reduced fitness in cell culture of HIV-1 with nonnucleoside reverse transcriptase inhibitor-resistant mutations correlates with relative levels of reverse transcriptase content and RNase H activity in virions.
Wang J; Bambara RA; Demeter LM; Dykes C
J Virol; 2010 Sep; 84(18):9377-89. PubMed ID: 20592075
[TBL] [Abstract][Full Text] [Related]
18. HIV-1 integrase and RNase H activities as therapeutic targets.
Andréola ML; De Soultrait VR; Fournier M; Parissi V; Desjobert C; Litvak S
Expert Opin Ther Targets; 2002 Aug; 6(4):433-46. PubMed ID: 12223059
[TBL] [Abstract][Full Text] [Related]
19. Past and future. Current drugs targeting HIV-1 integrase and reverse transcriptase-associated ribonuclease H activity: single and dual active site inhibitors.
Esposito F; Tramontano E
Antivir Chem Chemother; 2014 Jan; 23(4):129-44. PubMed ID: 24150519
[TBL] [Abstract][Full Text] [Related]
20. Molecular Docking and Molecular Dynamics Simulation Based Approach to Explore the Dual Inhibitor Against HIV-1 Reverse Transcriptase and Integrase.
Chander S; Pandey RK; Penta A; Choudhary BS; Sharma M; Malik R; Prajapati VK; Murugesan S
Comb Chem High Throughput Screen; 2017; 20(8):734-746. PubMed ID: 28641512
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
