92 related articles for article (PubMed ID: 27765510)
41. Achieving multi-isoform PI3K inhibition in a series of substituted 3,4-dihydro-2H-benzo[1,4]oxazines.
Perry B; Alexander R; Bennett G; Buckley G; Ceska T; Crabbe T; Dale V; Gowers L; Horsley H; James L; Jenkins K; Crépy K; Kulisa C; Lightfoot H; Lock C; Mack S; Morgan T; Nicolas AL; Pitt W; Sabin V; Wright S
Bioorg Med Chem Lett; 2008 Aug; 18(16):4700-4. PubMed ID: 18644721
[TBL] [Abstract][Full Text] [Related]
42. cUMP hydrolysis by PDE3A.
Berrisch S; Ostermeyer J; Kaever V; Kälble S; Hilfiker-Kleiner D; Seifert R; Schneider EH
Naunyn Schmiedebergs Arch Pharmacol; 2017 Mar; 390(3):269-280. PubMed ID: 27975297
[TBL] [Abstract][Full Text] [Related]
43. Inhibition of DNA-dependent protein kinase induces accelerated senescence in irradiated human cancer cells.
Azad A; Jackson S; Cullinane C; Natoli A; Neilsen PM; Callen DF; Maira SM; Hackl W; McArthur GA; Solomon B
Mol Cancer Res; 2011 Dec; 9(12):1696-707. PubMed ID: 22009179
[TBL] [Abstract][Full Text] [Related]
44. Design and synthesis of novel 6-aryl substituted 4-anilinequinazoline derivatives as potential PI3Kδ inhibitors.
Xin M; Hei YY; Zhang H; Shen Y; Zhang SQ
Bioorg Med Chem Lett; 2017 May; 27(9):1972-1977. PubMed ID: 28325601
[TBL] [Abstract][Full Text] [Related]
45. Differential regulation of human platelet responses by cGMP inhibited and stimulated cAMP phosphodiesterases.
Manns JM; Brenna KJ; Colman RW; Sheth SB
Thromb Haemost; 2002 May; 87(5):873-9. PubMed ID: 12038792
[TBL] [Abstract][Full Text] [Related]
46. Discovery of potent chromen-4-one inhibitors of the DNA-dependent protein kinase (DNA-PK) using a small-molecule library approach.
Hardcastle IR; Cockcroft X; Curtin NJ; El-Murr MD; Leahy JJ; Stockley M; Golding BT; Rigoreau L; Richardson C; Smith GC; Griffin RJ
J Med Chem; 2005 Dec; 48(24):7829-46. PubMed ID: 16302822
[TBL] [Abstract][Full Text] [Related]
47. QSAR study of antiplatelet agents.
Katritzky AR; Pacureanu LM; Slavov S; Dobchev DA; Karelson M
Bioorg Med Chem; 2006 Nov; 14(22):7490-500. PubMed ID: 16945540
[TBL] [Abstract][Full Text] [Related]
48. Synthesis, antiplatelet and in silico evaluations of novel N-substituted-phenylamino-5-methyl-1H-1,2,3-triazole-4-carbohydrazides.
Jordão AK; Ferreira VF; Lima ES; de Souza MC; Carlos EC; Castro HC; Geraldo RB; Rodrigues CR; Almeida MC; Cunha AC
Bioorg Med Chem; 2009 May; 17(10):3713-9. PubMed ID: 19380229
[TBL] [Abstract][Full Text] [Related]
49. Discovery of 4-morpholino-6-aryl-1H-pyrazolo[3,4-d]pyrimidines as highly potent and selective ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR): optimization of the 6-aryl substituent.
Verheijen JC; Richard DJ; Curran K; Kaplan J; Lefever M; Nowak P; Malwitz DJ; Brooijmans N; Toral-Barza L; Zhang WG; Lucas J; Hollander I; Ayral-Kaloustian S; Mansour TS; Yu K; Zask A
J Med Chem; 2009 Dec; 52(24):8010-24. PubMed ID: 19894727
[TBL] [Abstract][Full Text] [Related]
50. New platelet aggregation inhibitors based on pyridazinone moiety.
Costas T; Costas-Lago MC; Vila N; Besada P; Cano E; Terán C
Eur J Med Chem; 2015 Apr; 94():113-22. PubMed ID: 25757094
[TBL] [Abstract][Full Text] [Related]
51. Synthesis and evaluation of antiplatelet activity of trihydroxychalcone derivatives.
Zhao LM; Jin HS; Sun LP; Piao HR; Quan ZS
Bioorg Med Chem Lett; 2005 Nov; 15(22):5027-9. PubMed ID: 16169724
[TBL] [Abstract][Full Text] [Related]
52. DNA-dependent protein kinase (DNA-PK) inhibitors. Synthesis and biological activity of quinolin-4-one and pyridopyrimidin-4-one surrogates for the chromen-4-one chemotype.
Cano C; Barbeau OR; Bailey C; Cockcroft XL; Curtin NJ; Duggan H; Frigerio M; Golding BT; Hardcastle IR; Hummersone MG; Knights C; Menear KA; Newell DR; Richardson CJ; Smith GC; Spittle B; Griffin RJ
J Med Chem; 2010 Dec; 53(24):8498-507. PubMed ID: 21080722
[TBL] [Abstract][Full Text] [Related]
53. Role of phosphodiesterase type 3A and 3B in regulating platelet and cardiac function using subtype-selective knockout mice.
Sun B; Li H; Shakur Y; Hensley J; Hockman S; Kambayashi J; Manganiello VC; Liu Y
Cell Signal; 2007 Aug; 19(8):1765-71. PubMed ID: 17482796
[TBL] [Abstract][Full Text] [Related]
54. Pyrazole derivatives as inhibitors of arachidonic acid-induced platelet aggregation.
Levent S; Çalışkan B; Çiftçi M; Özkan Y; Yenicesu I; Ünver H; Banoglu E
Eur J Med Chem; 2013 Jun; 64():42-53. PubMed ID: 23639653
[TBL] [Abstract][Full Text] [Related]
55. Aryl morpholino triazenes inhibit cytochrome P450 1A1 and 1B1.
Lee D; Perez P; Jackson W; Chin T; Galbreath M; Fronczek FR; Isovitsch R; Iimoto DS
Bioorg Med Chem Lett; 2016 Jul; 26(14):3243-3247. PubMed ID: 27265259
[TBL] [Abstract][Full Text] [Related]
56. Synthesis and evaluation of novel 2-pyridone derivatives as inhibitors of phosphodiesterase3 (PDE3): a target for heart failure and platelet aggregation.
Ravinder M; Mahendar B; Mattapally S; Hamsini KV; Reddy TN; Rohit C; Srinivas K; Banerjee SK; Rao VJ
Bioorg Med Chem Lett; 2012 Sep; 22(18):6010-5. PubMed ID: 22897945
[TBL] [Abstract][Full Text] [Related]
57. Synthesis of 2H-benzo[b][1,4]oxazin-3(4H)-one derivatives as platelet aggregation inhibitors.
Tian X; Wang LY; Xia S; Li ZB; Liu XH; Yuan Y; Fang L; Zuo H
Bioorg Med Chem Lett; 2012 Jan; 22(1):204-6. PubMed ID: 22137848
[TBL] [Abstract][Full Text] [Related]
58. Potent inhibitors of phosphatidylinositol 3 (PI3) kinase that have antiproliferative activity only when delivered as prodrug forms.
O'Brien NJ; Amran S; Medan J; Cleary B; Deady LW; Jennings IG; Thompson PE; Abbott BM
ChemMedChem; 2013 Jun; 8(6):914-8. PubMed ID: 23568455
[TBL] [Abstract][Full Text] [Related]
59. Synthesis, Bioevaluation, Structure-Activity Relationship and Docking Studies of Natural Product Inspired (Z)-3-benzylideneisobenzofuran-1(3H)-ones as Highly Potent antioxidants and Antiplatelet agents.
Shyamlal BRK; Yadav L; Tiwari MK; Mathur M; Prikhodko JI; Mashevskaya IV; Yadav DK; Chaudhary S
Sci Rep; 2020 Feb; 10(1):2307. PubMed ID: 32047204
[TBL] [Abstract][Full Text] [Related]
60. Design, synthesis of novel tryptophan derivatives for antiplatelet aggregation activity based on tripeptide pENW (pGlu-Asn-Trp).
Xie Z; Feng S; Wang Y; Cao C; Huang J; Chen Y; Kong Y; Li Z
Eur J Med Chem; 2015 Sep; 102():363-74. PubMed ID: 26298494
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]