BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 27765848)

  • 1. Mitochondrial Targeting of Metformin Enhances Its Activity against Pancreatic Cancer.
    Boukalova S; Stursa J; Werner L; Ezrova Z; Cerny J; Bezawork-Geleta A; Pecinova A; Dong L; Drahota Z; Neuzil J
    Mol Cancer Ther; 2016 Dec; 15(12):2875-2886. PubMed ID: 27765848
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Modified Metformin as a More Potent Anticancer Drug: Mitochondrial Inhibition, Redox Signaling, Antiproliferative Effects and Future EPR Studies.
    Kalyanaraman B; Cheng G; Hardy M; Ouari O; Sikora A; Zielonka J; Dwinell MB
    Cell Biochem Biophys; 2017 Dec; 75(3-4):311-317. PubMed ID: 28429253
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mitochondria-Targeted Analogues of Metformin Exhibit Enhanced Antiproliferative and Radiosensitizing Effects in Pancreatic Cancer Cells.
    Cheng G; Zielonka J; Ouari O; Lopez M; McAllister D; Boyle K; Barrios CS; Weber JJ; Johnson BD; Hardy M; Dwinell MB; Kalyanaraman B
    Cancer Res; 2016 Jul; 76(13):3904-15. PubMed ID: 27216187
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting mitochondrial STAT3 with the novel phospho-valproic acid (MDC-1112) inhibits pancreatic cancer growth in mice.
    Mackenzie GG; Huang L; Alston N; Ouyang N; Vrankova K; Mattheolabakis G; Constantinides PP; Rigas B
    PLoS One; 2013; 8(5):e61532. PubMed ID: 23650499
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting the metabolic plasticity of multiple myeloma with FDA-approved ritonavir and metformin.
    Dalva-Aydemir S; Bajpai R; Martinez M; Adekola KU; Kandela I; Wei C; Singhal S; Koblinski JE; Raje NS; Rosen ST; Shanmugam M
    Clin Cancer Res; 2015 Mar; 21(5):1161-71. PubMed ID: 25542900
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mitochondria-targeted metformin (mitomet) inhibits lung cancer in cellular models and in mice by enhancing the generation of reactive oxygen species.
    Shameem M; Bagherpoor AJ; Nakhi A; Dosa P; Georg G; Kassie F
    Mol Carcinog; 2023 Nov; 62(11):1619-1629. PubMed ID: 37401866
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Itraconazole inhibits proliferation of pancreatic cancer cells through activation of Bak-1.
    Jiang F; Xing HS; Chen WY; Du J; Ruan YL; Lin AY; Zhou CZ
    J Cell Biochem; 2019 Mar; 120(3):4333-4341. PubMed ID: 30260036
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metformin suppresses the invasive ability of pancreatic cancer cells by blocking autocrine TGF‑β1 signaling.
    Duan W; Qian W; Zhou C; Cao J; Qin T; Xiao Y; Cheng L; Li J; Chen K; Li X; Ma J; Ma Q
    Oncol Rep; 2018 Sep; 40(3):1495-1502. PubMed ID: 29956804
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antibiotic drug levofloxacin inhibits proliferation and induces apoptosis of lung cancer cells through inducing mitochondrial dysfunction and oxidative damage.
    Song M; Wu H; Wu S; Ge T; Wang G; Zhou Y; Sheng S; Jiang J
    Biomed Pharmacother; 2016 Dec; 84():1137-1143. PubMed ID: 27780143
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phenylethynylbenzyl-modified biguanides inhibit pancreatic cancer tumor growth.
    Hébert A; Parisotto M; Rowell MC; Doré A; Fernandez Ruiz A; Lefrançois G; Kalegari P; Ferbeyre G; Schmitzer AR
    Sci Rep; 2021 May; 11(1):9854. PubMed ID: 33972583
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Combinatorial Screening of Pancreatic Adenocarcinoma Reveals Sensitivity to Drug Combinations Including Bromodomain Inhibitor Plus Neddylation Inhibitor.
    Langdon CG; Platt JT; Means RE; Iyidogan P; Mamillapalli R; Klein M; Held MA; Lee JW; Koo JS; Hatzis C; Hochster HS; Stern DF
    Mol Cancer Ther; 2017 Jun; 16(6):1041-1053. PubMed ID: 28292938
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Bcl-xL inhibition by molecular-targeting drugs sensitizes human pancreatic cancer cells to TRAIL.
    Hari Y; Harashima N; Tajima Y; Harada M
    Oncotarget; 2015 Dec; 6(39):41902-15. PubMed ID: 26506422
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metformin inhibits human breast cancer cell growth by promoting apoptosis via a ROS-independent pathway involving mitochondrial dysfunction: pivotal role of superoxide dismutase (SOD).
    Sharma P; Kumar S
    Cell Oncol (Dordr); 2018 Dec; 41(6):637-650. PubMed ID: 30088260
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selective Disruption of Respiratory Supercomplexes as a New Strategy to Suppress Her2
    Rohlenova K; Sachaphibulkij K; Stursa J; Bezawork-Geleta A; Blecha J; Endaya B; Werner L; Cerny J; Zobalova R; Goodwin J; Spacek T; Alizadeh Pesdar E; Yan B; Nguyen MN; Vondrusova M; Sobol M; Jezek P; Hozak P; Truksa J; Rohlena J; Dong LF; Neuzil J
    Antioxid Redox Signal; 2017 Jan; 26(2):84-103. PubMed ID: 27392540
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metformin Inhibits Proliferation and Tumor Growth of QGP-1 Pancreatic Neuroendocrine Tumor Cells by Inducing Cell Cycle Arrest and Apoptosis.
    Yamana H; Kato K; Kobara H; Fujihara S; Fujita K; Namima D; Fujita N; Kobayashi K; Kamada H; Morishita A; Tsutsui K; Iwama H; Masaki T
    Anticancer Res; 2020 Jan; 40(1):121-132. PubMed ID: 31892560
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Metformin Suppresses Self-Renewal Ability and Tumorigenicity of Osteosarcoma Stem Cells via Reactive Oxygen Species-Mediated Apoptosis and Autophagy.
    Zhao B; Luo J; Wang Y; Zhou L; Che J; Wang F; Peng S; Zhang G; Shang P
    Oxid Med Cell Longev; 2019; 2019():9290728. PubMed ID: 31827709
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Oncogenic HSP60 regulates mitochondrial oxidative phosphorylation to support Erk1/2 activation during pancreatic cancer cell growth.
    Zhou C; Sun H; Zheng C; Gao J; Fu Q; Hu N; Shao X; Zhou Y; Xiong J; Nie K; Zhou H; Shen L; Fang H; Lyu J
    Cell Death Dis; 2018 Feb; 9(2):161. PubMed ID: 29415987
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of Isoprenylcysteine Carboxylmethyltransferase Induces Cell-Cycle Arrest and Apoptosis through p21 and p21-Regulated BNIP3 Induction in Pancreatic Cancer.
    Manu KA; Chai TF; Teh JT; Zhu WL; Casey PJ; Wang M
    Mol Cancer Ther; 2017 May; 16(5):914-923. PubMed ID: 28167504
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bazedoxifene as a Novel GP130 Inhibitor for Pancreatic Cancer Therapy.
    Wu X; Cao Y; Xiao H; Li C; Lin J
    Mol Cancer Ther; 2016 Nov; 15(11):2609-2619. PubMed ID: 27535971
    [TBL] [Abstract][Full Text] [Related]  

  • 20. JTC801 Induces pH-dependent Death Specifically in Cancer Cells and Slows Growth of Tumors in Mice.
    Song X; Zhu S; Xie Y; Liu J; Sun L; Zeng D; Wang P; Ma X; Kroemer G; Bartlett DL; Billiar TR; Lotze MT; Zeh HJ; Kang R; Tang D
    Gastroenterology; 2018 Apr; 154(5):1480-1493. PubMed ID: 29248440
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.