These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
492 related articles for article (PubMed ID: 27768897)
1. Toxic PR Poly-Dipeptides Encoded by the C9orf72 Repeat Expansion Target LC Domain Polymers. Lin Y; Mori E; Kato M; Xiang S; Wu L; Kwon I; McKnight SL Cell; 2016 Oct; 167(3):789-802.e12. PubMed ID: 27768897 [TBL] [Abstract][Full Text] [Related]
2. Toxic PR Shi KY; Mori E; Nizami ZF; Lin Y; Kato M; Xiang S; Wu LC; Ding M; Yu Y; Gall JG; McKnight SL Proc Natl Acad Sci U S A; 2017 Feb; 114(7):E1111-E1117. PubMed ID: 28069952 [TBL] [Abstract][Full Text] [Related]
3. C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles. Lee KH; Zhang P; Kim HJ; Mitrea DM; Sarkar M; Freibaum BD; Cika J; Coughlin M; Messing J; Molliex A; Maxwell BA; Kim NC; Temirov J; Moore J; Kolaitis RM; Shaw TI; Bai B; Peng J; Kriwacki RW; Taylor JP Cell; 2016 Oct; 167(3):774-788.e17. PubMed ID: 27768896 [TBL] [Abstract][Full Text] [Related]
4. Poly-PR in C9ORF72-Related Amyotrophic Lateral Sclerosis/Frontotemporal Dementia Causes Neurotoxicity by Clathrin-Dependent Endocytosis. Wang R; Xu X; Hao Z; Zhang S; Wu D; Sun H; Mu C; Ren H; Wang G Neurosci Bull; 2019 Oct; 35(5):889-900. PubMed ID: 31148094 [TBL] [Abstract][Full Text] [Related]
5. Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS. Jovičić A; Mertens J; Boeynaems S; Bogaert E; Chai N; Yamada SB; Paul JW; Sun S; Herdy JR; Bieri G; Kramer NJ; Gage FH; Van Den Bosch L; Robberecht W; Gitler AD Nat Neurosci; 2015 Sep; 18(9):1226-9. PubMed ID: 26308983 [TBL] [Abstract][Full Text] [Related]
6. Poly-dipeptides encoded by the C9orf72 repeats bind nucleoli, impede RNA biogenesis, and kill cells. Kwon I; Xiang S; Kato M; Wu L; Theodoropoulos P; Wang T; Kim J; Yun J; Xie Y; McKnight SL Science; 2014 Sep; 345(6201):1139-45. PubMed ID: 25081482 [TBL] [Abstract][Full Text] [Related]
8. The DNA damage response (DDR) is induced by the C9orf72 repeat expansion in amyotrophic lateral sclerosis. Farg MA; Konopka A; Soo KY; Ito D; Atkin JD Hum Mol Genet; 2017 Aug; 26(15):2882-2896. PubMed ID: 28481984 [TBL] [Abstract][Full Text] [Related]
9. Cell Biology. Clogging information flow in ALS. Paul JW; Gitler AD Science; 2014 Sep; 345(6201):1118-9. PubMed ID: 25190778 [No Abstract] [Full Text] [Related]
10. Soluble and insoluble dipeptide repeat protein measurements in C9orf72-frontotemporal dementia brains show regional differential solubility and correlation of poly-GR with clinical severity. Quaegebeur A; Glaria I; Lashley T; Isaacs AM Acta Neuropathol Commun; 2020 Nov; 8(1):184. PubMed ID: 33168090 [TBL] [Abstract][Full Text] [Related]
11. C9orf72-generated poly-GR and poly-PR do not directly interfere with nucleocytoplasmic transport. Vanneste J; Vercruysse T; Boeynaems S; Sicart A; Van Damme P; Daelemans D; Van Den Bosch L Sci Rep; 2019 Oct; 9(1):15728. PubMed ID: 31673013 [TBL] [Abstract][Full Text] [Related]
12. Proline/arginine dipeptide repeat polymers derail protein folding in amyotrophic lateral sclerosis. Babu M; Favretto F; de Opakua AI; Rankovic M; Becker S; Zweckstetter M Nat Commun; 2021 Jun; 12(1):3396. PubMed ID: 34099711 [TBL] [Abstract][Full Text] [Related]
13. Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM. Loveland AB; Svidritskiy E; Susorov D; Lee S; Park A; Zvornicanin S; Demo G; Gao FB; Korostelev AA Nat Commun; 2022 May; 13(1):2776. PubMed ID: 35589706 [TBL] [Abstract][Full Text] [Related]
14. Disrupted phase behavior of FUS underlies poly-PR-induced DNA damage in amyotrophic lateral sclerosis. Wang Y; Liu L; Chen H; Yang Y; Mu C; Ren H; Liu Y; Yu L; Fang Q; Wang G; Hao Z Hum Mol Genet; 2023 Dec; 33(1):64-77. PubMed ID: 37756636 [TBL] [Abstract][Full Text] [Related]
15. Dipeptide repeat derived from C9orf72 hexanucleotide expansions forms amyloids or natively unfolded structures in vitro. Brasseur L; Coens A; Waeytens J; Melki R; Bousset L Biochem Biophys Res Commun; 2020 May; 526(2):410-416. PubMed ID: 32223927 [TBL] [Abstract][Full Text] [Related]
16. Characterization of the dipeptide repeat protein in the molecular pathogenesis of c9FTD/ALS. Yamakawa M; Ito D; Honda T; Kubo K; Noda M; Nakajima K; Suzuki N Hum Mol Genet; 2015 Mar; 24(6):1630-45. PubMed ID: 25398948 [TBL] [Abstract][Full Text] [Related]
18. Pathogenic determinants and mechanisms of ALS/FTD linked to hexanucleotide repeat expansions in the C9orf72 gene. Wen X; Westergard T; Pasinelli P; Trotti D Neurosci Lett; 2017 Jan; 636():16-26. PubMed ID: 27619540 [TBL] [Abstract][Full Text] [Related]
19. There has been an awakening: Emerging mechanisms of C9orf72 mutations in FTD/ALS. Gitler AD; Tsuiji H Brain Res; 2016 Sep; 1647():19-29. PubMed ID: 27059391 [TBL] [Abstract][Full Text] [Related]
20. Poly(GR) in C9ORF72-Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons. Lopez-Gonzalez R; Lu Y; Gendron TF; Karydas A; Tran H; Yang D; Petrucelli L; Miller BL; Almeida S; Gao FB Neuron; 2016 Oct; 92(2):383-391. PubMed ID: 27720481 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]