176 related articles for article (PubMed ID: 27770449)
1. Polymorphic variation in TPMT is the principal determinant of TPMT phenotype: A meta-analysis of three genome-wide association studies.
Tamm R; Mägi R; Tremmel R; Winter S; Mihailov E; Smid A; Möricke A; Klein K; Schrappe M; Stanulla M; Houlston R; Weinshilboum R; Mlinarič Raščan I; Metspalu A; Milani L; Schwab M; Schaeffeler E
Clin Pharmacol Ther; 2017 May; 101(5):684-695. PubMed ID: 27770449
[TBL] [Abstract][Full Text] [Related]
2. Genomewide Approach Validates Thiopurine Methyltransferase Activity Is a Monogenic Pharmacogenomic Trait.
Liu C; Yang W; Pei D; Cheng C; Smith C; Landier W; Hageman L; Chen Y; Yang JJ; Crews KR; Kornegay N; Karol SE; Wong FL; Jeha S; Sandlund JT; Ribeiro RC; Rubnitz JE; Metzger ML; Pui CH; Evans WE; Bhatia S; Relling MV
Clin Pharmacol Ther; 2017 Mar; 101(3):373-381. PubMed ID: 27564568
[TBL] [Abstract][Full Text] [Related]
3. Clinical pharmacogenomics of thiopurine S-methyltransferase.
Zhou S
Curr Clin Pharmacol; 2006 Jan; 1(1):119-28. PubMed ID: 18666383
[TBL] [Abstract][Full Text] [Related]
4. Impact of NUDT15 genetics on severe thiopurine-related hematotoxicity in patients with European ancestry.
Schaeffeler E; Jaeger SU; Klumpp V; Yang JJ; Igel S; Hinze L; Stanulla M; Schwab M
Genet Med; 2019 Sep; 21(9):2145-2150. PubMed ID: 30728528
[TBL] [Abstract][Full Text] [Related]
5. Comprehensive study of thiopurine methyltransferase genotype, phenotype, and genotype-phenotype discrepancies in Sweden.
Zimdahl Kahlin A; Helander S; Skoglund K; Söderkvist P; Mårtensson LG; Appell ML
Biochem Pharmacol; 2019 Jun; 164():263-272. PubMed ID: 31005613
[TBL] [Abstract][Full Text] [Related]
6. PACSIN2 polymorphism influences TPMT activity and mercaptopurine-related gastrointestinal toxicity.
Stocco G; Yang W; Crews KR; Thierfelder WE; Decorti G; Londero M; Franca R; Rabusin M; Valsecchi MG; Pei D; Cheng C; Paugh SW; Ramsey LB; Diouf B; McCorkle JR; Jones TS; Pui CH; Relling MV; Evans WE
Hum Mol Genet; 2012 Nov; 21(21):4793-804. PubMed ID: 22846425
[TBL] [Abstract][Full Text] [Related]
7. Thiopurine S-methyltransferase phenotype-genotype correlation in children with acute lymphoblastic leukemia.
Chrzanowska M; Kuehn M; Januszkiewicz-Lewandowska D; Kurzawski M; Droździk M
Acta Pol Pharm; 2012; 69(3):405-10. PubMed ID: 22594254
[TBL] [Abstract][Full Text] [Related]
8. Thiopurine methyltransferase polymorphic tandem repeat: genotype-phenotype correlation analysis.
Yan L; Zhang S; Eiff B; Szumlanski CL; Powers M; O'Brien JF; Weinshilboum RM
Clin Pharmacol Ther; 2000 Aug; 68(2):210-9. PubMed ID: 10976552
[TBL] [Abstract][Full Text] [Related]
9. Genotype-phenotype correlation for thiopurine S-methyltransferase in healthy Italian subjects.
Rossi AM; Bianchi M; Guarnieri C; Barale R; Pacifici GM
Eur J Clin Pharmacol; 2001 Apr; 57(1):51-4. PubMed ID: 11372592
[TBL] [Abstract][Full Text] [Related]
10. The thiopurine S-methyltransferase gene locus -- implications for clinical pharmacogenomics.
McLeod HL; Siva C
Pharmacogenomics; 2002 Jan; 3(1):89-98. PubMed ID: 11966406
[TBL] [Abstract][Full Text] [Related]
11. Azathioprine therapy and adverse drug reactions in patients with inflammatory bowel disease: impact of thiopurine S-methyltransferase polymorphism.
Schwab M; Schäffeler E; Marx C; Fischer C; Lang T; Behrens C; Gregor M; Eichelbaum M; Zanger UM; Kaskas BA
Pharmacogenetics; 2002 Aug; 12(6):429-36. PubMed ID: 12172211
[TBL] [Abstract][Full Text] [Related]
12. Characterisation of novel defective thiopurine S-methyltransferase allelic variants.
Garat A; Cauffiez C; Renault N; Lo-Guidice JM; Allorge D; Chevalier D; Houdret N; Chavatte P; Loriot MA; Gala JL; Broly F
Biochem Pharmacol; 2008 Aug; 76(3):404-15. PubMed ID: 18602085
[TBL] [Abstract][Full Text] [Related]
13. Genotypic and phenotypic analysis of the polymorphic thiopurine S-methyltransferase gene (TPMT) in a European population.
Spire-Vayron de la Moureyre C; Debuysere H; Mastain B; Vinner E; Marez D; Lo Guidice JM; Chevalier D; Brique S; Motte K; Colombel JF; Turck D; Noel C; Flipo RM; Pol A; Lhermitte M; Lafitte JJ; Libersa C; Broly F
Br J Pharmacol; 1998 Oct; 125(4):879-87. PubMed ID: 9831928
[TBL] [Abstract][Full Text] [Related]
14. Thiopurine S-methyltransferase (TPMT) pharmacogenetics: three new mutations and haplotype analysis in the Estonian population.
Tamm R; Oselin K; Kallassalu K; Magi R; Anier K; Remm M; Metspalu A
Clin Chem Lab Med; 2008; 46(7):974-9. PubMed ID: 18605963
[TBL] [Abstract][Full Text] [Related]
15. Thiopurine Methyltransferase Genetic Polymorphisms and Activity and Metabolic Products of Azathioprine in Patients with Inflammatory Bowel Disease.
Pashazadeh P; Marjani A; Asadi J; Khoshnia M
Endocr Metab Immune Disord Drug Targets; 2019; 19(4):541-547. PubMed ID: 30451123
[TBL] [Abstract][Full Text] [Related]
16. Genetic polymorphism of inosine-triphosphate-pyrophosphatase influences mercaptopurine metabolism and toxicity during treatment of acute lymphoblastic leukemia individualized for thiopurine-S-methyl-transferase status.
Stocco G; Crews KR; Evans WE
Expert Opin Drug Saf; 2010 Jan; 9(1):23-37. PubMed ID: 20021291
[TBL] [Abstract][Full Text] [Related]
17. Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine.
Evans WE; Hon YY; Bomgaars L; Coutre S; Holdsworth M; Janco R; Kalwinsky D; Keller F; Khatib Z; Margolin J; Murray J; Quinn J; Ravindranath Y; Ritchey K; Roberts W; Rogers ZR; Schiff D; Steuber C; Tucci F; Kornegay N; Krynetski EY; Relling MV
J Clin Oncol; 2001 Apr; 19(8):2293-301. PubMed ID: 11304783
[TBL] [Abstract][Full Text] [Related]
18. Allelic variants of the thiopurine S-methyltransferase deficiency in patients with ulcerative colitis and in healthy controls.
Corominas H; Domènech M; González D; Diaz C; Roca M; García-González MA; Peña S; Baiget M
Am J Gastroenterol; 2000 Sep; 95(9):2313-7. PubMed ID: 11007234
[TBL] [Abstract][Full Text] [Related]
19. Association between thiopurine S-methyltransferase polymorphisms and thiopurine-induced adverse drug reactions in patients with inflammatory bowel disease: a meta-analysis.
Liu YP; Wu HY; Yang X; Xu HQ; Li YC; Shi DC; Huang JF; Huang Q; Fu WL
PLoS One; 2015; 10(3):e0121745. PubMed ID: 25799415
[TBL] [Abstract][Full Text] [Related]
20. Thiopurine methyltransferase (TPMT) genotype and early treatment response to mercaptopurine in childhood acute lymphoblastic leukemia.
Stanulla M; Schaeffeler E; Flohr T; Cario G; Schrauder A; Zimmermann M; Welte K; Ludwig WD; Bartram CR; Zanger UM; Eichelbaum M; Schrappe M; Schwab M
JAMA; 2005 Mar; 293(12):1485-9. PubMed ID: 15784872
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]