BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

385 related articles for article (PubMed ID: 27771599)

  • 1. Design, synthesis and biological evaluation of [1,2,3]triazolo[4,5-d]pyrimidine derivatives possessing a hydrazone moiety as antiproliferative agents.
    Li ZH; Yang DX; Geng PF; Zhang J; Wei HM; Hu B; Guo Q; Zhang XH; Guo WG; Zhao B; Yu B; Ma LY; Liu HM
    Eur J Med Chem; 2016 Nov; 124():967-980. PubMed ID: 27771599
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis and in vitro biological evaluation of novel [1,2,3]triazolo[4,5-d]pyrimidine derivatives containing a thiosemicarbazide moiety.
    Geng PF; Liu XQ; Zhao TQ; Wang CC; Li ZH; Zhang J; Wei HM; Hu B; Ma LY; Liu HM
    Eur J Med Chem; 2018 Feb; 146():147-156. PubMed ID: 29407946
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel [1,2,3]triazolo[4,5-d]pyrimidine derivatives containing hydrazone fragment as potent and selective anticancer agents.
    Xu C; Zhou W; Dong G; Qiao H; Peng J; Jia P; Li Y; Liu H; Sun K; Zhao W
    Bioorg Chem; 2020 Dec; 105():104424. PubMed ID: 33161253
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design and synthesis of novel 1,2,3-triazole-pyrimidine hybrids as potential anticancer agents.
    Ma LY; Pang LP; Wang B; Zhang M; Hu B; Xue DQ; Shao KP; Zhang BL; Liu Y; Zhang E; Liu HM
    Eur J Med Chem; 2014 Oct; 86():368-80. PubMed ID: 25180925
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis, anticancer activity and effects on cell cycle profile and apoptosis of novel thieno[2,3-d]pyrimidine and thieno[3,2-e] triazolo[4,3-c]pyrimidine derivatives.
    Kandeel MM; Refaat HM; Kassab AE; Shahin IG; Abdelghany TM
    Eur J Med Chem; 2015 Jan; 90():620-32. PubMed ID: 25499930
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and biological evaluation of novel thieno[3,2-d]pyrimidine derivatives containing diaryl urea moiety as potent antitumor agents.
    Liu Z; Wang Y; Lin H; Zuo D; Wang L; Zhao Y; Gong P
    Eur J Med Chem; 2014 Oct; 85():215-27. PubMed ID: 25086238
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design and synthesis of novel 1,2,3-triazole-pyrimidine-urea hybrids as potential anticancer agents.
    Ma LY; Wang B; Pang LP; Zhang M; Wang SQ; Zheng YC; Shao KP; Xue DQ; Liu HM
    Bioorg Med Chem Lett; 2015 Mar; 25(5):1124-8. PubMed ID: 25655718
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and antitumor activity of pyrido [2,3-d]pyrimidine and pyrido[2,3-d] [1,2,4]triazolo[4,3-a]pyrimidine derivatives that induce apoptosis through G1 cell-cycle arrest.
    Fares M; Abou-Seri SM; Abdel-Aziz HA; Abbas SE; Youssef MM; Eladwy RA
    Eur J Med Chem; 2014 Aug; 83():155-66. PubMed ID: 24956552
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A novel [1,2,4] triazolo [1,5-a] pyrimidine-based phenyl-linked steroid dimer: synthesis and its cytotoxic activity.
    Yu B; Shi XJ; Zheng YF; Fang Y; Zhang E; Yu DQ; Liu HM
    Eur J Med Chem; 2013 Nov; 69():323-30. PubMed ID: 24077182
    [TBL] [Abstract][Full Text] [Related]  

  • 10. [1,2,3]Triazolo[4,5-d]pyrimidine derivatives incorporating (thio)urea moiety as a novel scaffold for LSD1 inhibitors.
    Li ZH; Ma JL; Liu GZ; Zhang XH; Qin TT; Ren WH; Zhao TQ; Chen XH; Zhang ZQ
    Eur J Med Chem; 2020 Feb; 187():111989. PubMed ID: 31881456
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design and synthesis of novel pyrazolo[1,5-a]pyrimidine derivatives bearing nitrogen mustard moiety and evaluation of their antitumor activity in vitro and in vivo.
    Zhao M; Ren H; Chang J; Zhang D; Yang Y; He Y; Qi C; Zhang H
    Eur J Med Chem; 2016 Aug; 119():183-96. PubMed ID: 27162123
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis and antiproliferative activity of novel 5-nitropyrimidine-2,4-diamine derivatives bearing alkyl acetate moiety.
    Zhao PL; Li YH; Yang HK; Chen P; Zhang B; Sun Q; Li Q; You WW
    Eur J Med Chem; 2016 Aug; 118():161-9. PubMed ID: 27128180
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and anticancer activities of novel 1,2,4-triazolo[3,4-a]phthalazine derivatives.
    Xue DQ; Zhang XY; Wang CJ; Ma LY; Zhu N; He P; Shao KP; Chen PJ; Gu YF; Zhang XS; Wang CF; Ji CH; Zhang QR; Liu HM
    Eur J Med Chem; 2014 Oct; 85():235-44. PubMed ID: 25086915
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Facile synthesis and antiproliferative activity of 7H-benzo[7,8]chromeno[2,3-d]pyrimidin-8-amines.
    Akrami H; Safavi M; Mirjalili BF; Dehghani Ashkezari M; Dadfar F; Mohaghegh N; Emami S; Salehi F; Nadri H; Ardestani SK; Firoozpour L; Khoobi M; Foroumadi A
    Eur J Med Chem; 2017 Feb; 127():128-136. PubMed ID: 28039771
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel [1,2,4]triazolo[1,5-a]pyrimidine derivatives as potent antitubulin agents: Design, multicomponent synthesis and antiproliferative activities.
    Yang F; Yu LZ; Diao PC; Jian XE; Zhou MF; Jiang CS; You WW; Ma WF; Zhao PL
    Bioorg Chem; 2019 Nov; 92():103260. PubMed ID: 31525523
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and anti-tumor activities of N'-benzylidene-2-(4-oxothieno[2,3-d]pyrimidin-3(4H)-yl)acetohydrazone derivatives.
    Lou J; Liu Z; Li Y; Zhou M; Zhang Z; Zheng S; Wang R; Li J
    Bioorg Med Chem Lett; 2011 Nov; 21(22):6662-6. PubMed ID: 21986587
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis and biological evaluation of novel 2,4-bismorpholinothieno[3,2-d]pyrimidine and 2-morpholinothieno[3,2-d]pyrimidinone derivatives as potent antitumor agents.
    Ye T; Han Y; Wang R; Yan P; Chen S; Hou Y; Zhao Y
    Bioorg Chem; 2020 Jun; 99():103796. PubMed ID: 32283346
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An unexpected Dimroth rearrangement leading to annelated thieno[3,2-d][1,2,3]triazolo[1,5-a]pyrimidines with potent antitumor activity.
    Lauria A; Patella C; Abbate I; Martorana A; Almerico AM
    Eur J Med Chem; 2013 Jul; 65():381-8. PubMed ID: 23747807
    [TBL] [Abstract][Full Text] [Related]  

  • 19. New annelated thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidines, with potent anticancer activity, designed through VLAK protocol.
    Lauria A; Abbate I; Patella C; Martorana A; Dattolo G; Almerico AM
    Eur J Med Chem; 2013 Apr; 62():416-24. PubMed ID: 23395722
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of thiazolo[5,4-d]pyrimidine derivatives as potent antiproliferative agents through the drug repurposing strategy.
    Li ZH; Zhang J; Liu XQ; Geng PF; Ma JL; Wang B; Zhao TQ; Zhao B; Wei HM; Wang C; Fu DJ; Yu B; Liu HM
    Eur J Med Chem; 2017 Jul; 135():204-212. PubMed ID: 28456031
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.