BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

621 related articles for article (PubMed ID: 27773676)

  • 1. The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
    Grüner S; Peter D; Weber R; Wohlbold L; Chung MY; Weichenrieder O; Valkov E; Igreja C; Izaurralde E
    Mol Cell; 2016 Nov; 64(3):467-479. PubMed ID: 27773676
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 4E-BPs require non-canonical 4E-binding motifs and a lateral surface of eIF4E to repress translation.
    Igreja C; Peter D; Weiler C; Izaurralde E
    Nat Commun; 2014 Sep; 5():4790. PubMed ID: 25179781
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.
    Grüner S; Weber R; Peter D; Chung MY; Igreja C; Valkov E; Izaurralde E
    Nucleic Acids Res; 2018 Jul; 46(13):6893-6908. PubMed ID: 30053226
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure of eIF4E in Complex with an eIF4G Peptide Supports a Universal Bipartite Binding Mode for Protein Translation.
    Miras M; Truniger V; Silva C; Verdaguer N; Aranda MA; Querol-Audí J
    Plant Physiol; 2017 Jul; 174(3):1476-1491. PubMed ID: 28522457
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular architecture of 4E-BP translational inhibitors bound to eIF4E.
    Peter D; Igreja C; Weber R; Wohlbold L; Weiler C; Ebertsch L; Weichenrieder O; Izaurralde E
    Mol Cell; 2015 Mar; 57(6):1074-1087. PubMed ID: 25702871
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1.
    Sekiyama N; Arthanari H; Papadopoulos E; Rodriguez-Mias RA; Wagner G; Léger-Abraham M
    Proc Natl Acad Sci U S A; 2015 Jul; 112(30):E4036-45. PubMed ID: 26170285
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The human eIF4E:4E-BP2 complex structure for studying hyperphosphorylation.
    Zeng J; Lu C; Huang X; Li Y
    Phys Chem Chem Phys; 2024 Apr; 26(14):10660-10672. PubMed ID: 38511550
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification and function of the second eIF4E-binding region in N-terminal domain of eIF4G: comparison with eIF4E-binding protein.
    Umenaga Y; Paku KS; In Y; Ishida T; Tomoo K
    Biochem Biophys Res Commun; 2011 Oct; 414(3):462-7. PubMed ID: 21964297
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mextli proteins use both canonical bipartite and novel tripartite binding modes to form eIF4E complexes that display differential sensitivity to 4E-BP regulation.
    Peter D; Weber R; Köne C; Chung MY; Ebertsch L; Truffault V; Weichenrieder O; Igreja C; Izaurralde E
    Genes Dev; 2015 Sep; 29(17):1835-49. PubMed ID: 26294658
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evaluating the conformation and binding interface of cap-binding proteins and complexes via ultraviolet photodissociation mass spectrometry.
    O'Brien JP; Mayberry LK; Murphy PA; Browning KS; Brodbelt JS
    J Proteome Res; 2013 Dec; 12(12):5867-77. PubMed ID: 24200290
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Two related trypanosomatid eIF4G homologues have functional differences compatible with distinct roles during translation initiation.
    Moura DM; Reis CR; Xavier CC; da Costa Lima TD; Lima RP; Carrington M; de Melo Neto OP
    RNA Biol; 2015; 12(3):305-19. PubMed ID: 25826663
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of Mitogen-activated Protein Kinase (MAPK)-interacting Kinase (MNK) Preferentially Affects Translation of mRNAs Containing Both a 5'-Terminal Cap and Hairpin.
    Korneeva NL; Song A; Gram H; Edens MA; Rhoads RE
    J Biol Chem; 2016 Feb; 291(7):3455-67. PubMed ID: 26668315
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Repressor binding to a dorsal regulatory site traps human eIF4E in a high cap-affinity state.
    Ptushkina M; von der Haar T; Karim MM; Hughes JM; McCarthy JE
    EMBO J; 1999 Jul; 18(14):4068-75. PubMed ID: 10406811
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural characterization of the Z RING-eIF4E complex reveals a distinct mode of control for eIF4E.
    Volpon L; Osborne MJ; Capul AA; de la Torre JC; Borden KL
    Proc Natl Acad Sci U S A; 2010 Mar; 107(12):5441-6. PubMed ID: 20212144
    [TBL] [Abstract][Full Text] [Related]  

  • 15. After fertilization of sea urchin eggs, eIF4G is post-translationally modified and associated with the cap-binding protein eIF4E.
    Oulhen N; Salaün P; Cosson B; Cormier P; Morales J
    J Cell Sci; 2007 Feb; 120(Pt 3):425-34. PubMed ID: 17213333
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G.
    Moerke NJ; Aktas H; Chen H; Cantel S; Reibarkh MY; Fahmy A; Gross JD; Degterev A; Yuan J; Chorev M; Halperin JA; Wagner G
    Cell; 2007 Jan; 128(2):257-67. PubMed ID: 17254965
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interaction of the eukaryotic initiation factor 4E with 4E-BP2 at a dynamic bipartite interface.
    Lukhele S; Bah A; Lin H; Sonenberg N; Forman-Kay JD
    Structure; 2013 Dec; 21(12):2186-96. PubMed ID: 24207126
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The unique Leishmania EIF4E4 N-terminus is a target for multiple phosphorylation events and participates in critical interactions required for translation initiation.
    de Melo Neto OP; da Costa Lima TD; Xavier CC; Nascimento LM; Romão TP; Assis LA; Pereira MM; Reis CR; Papadopoulou B
    RNA Biol; 2015; 12(11):1209-21. PubMed ID: 26338184
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Variability in eukaryotic initiation factor iso4E in Brassica rapa influences interactions with the viral protein linked to the genome of Turnip mosaic virus.
    Li G; Qian W; Zhang S; Zhang S; Li F; Zhang H; Fang Z; Wu J; Wang X; Sun R
    Sci Rep; 2018 Sep; 8(1):13588. PubMed ID: 30206242
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dynamic Interaction of Eukaryotic Initiation Factor 4G1 (eIF4G1) with eIF4E and eIF1 Underlies Scanning-Dependent and -Independent Translation.
    Haimov O; Sehrawat U; Tamarkin-Ben Harush A; Bahat A; Uzonyi A; Will A; Hiraishi H; Asano K; Dikstein R
    Mol Cell Biol; 2018 Sep; 38(18):. PubMed ID: 29987188
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 32.