BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

99 related articles for article (PubMed ID: 27777086)

  • 1. Interdomain interactions rearrangements control the reaction steps of a thermostable DNA alkyltransferase.
    Morrone C; Miggiano R; Serpe M; Massarotti A; Valenti A; Del Monaco G; Rossi M; Rossi F; Rizzi M; Perugino G; Ciaramella M
    Biochim Biophys Acta Gen Subj; 2017 Feb; 1861(2):86-96. PubMed ID: 27777086
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein.
    Perugino G; Miggiano R; Serpe M; Vettone A; Valenti A; Lahiri S; Rossi F; Rossi M; Rizzi M; Ciaramella M
    Nucleic Acids Res; 2015 Oct; 43(18):8801-16. PubMed ID: 26227971
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activity and regulation of archaeal DNA alkyltransferase: conserved protein involved in repair of DNA alkylation damage.
    Perugino G; Vettone A; Illiano G; Valenti A; Ferrara MC; Rossi M; Ciaramella M
    J Biol Chem; 2012 Feb; 287(6):4222-31. PubMed ID: 22167184
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crystal structure of a thermophilic O
    Rossi F; Morrone C; Massarotti A; Ferraris DM; Valenti A; Perugino G; Miggiano R
    Biochem Biophys Res Commun; 2018 Jun; 500(3):698-703. PubMed ID: 29684348
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Every OGT Is Illuminated … by Fluorescent and Synchrotron Lights.
    Miggiano R; Valenti A; Rossi F; Rizzi M; Perugino G; Ciaramella M
    Int J Mol Sci; 2017 Dec; 18(12):. PubMed ID: 29206193
    [No Abstract]   [Full Text] [Related]  

  • 6. Alkyltransferase-like protein clusters scan DNA rapidly over long distances and recruit NER to alkyl-DNA lesions.
    Rill N; Mukhortava A; Lorenz S; Tessmer I
    Proc Natl Acad Sci U S A; 2020 Apr; 117(17):9318-9328. PubMed ID: 32273391
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel thermostable protein-tag: optimization of the Sulfolobus solfataricus DNA- alkyl-transferase by protein engineering.
    Vettone A; Serpe M; Hidalgo A; Berenguer J; del Monaco G; Valenti A; Rossi M; Ciaramella M; Perugino G
    Extremophiles; 2016 Jan; 20(1):1-13. PubMed ID: 26499124
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural basis of O6-alkylguanine recognition by a bacterial alkyltransferase-like DNA repair protein.
    Aramini JM; Tubbs JL; Kanugula S; Rossi P; Ertekin A; Maglaqui M; Hamilton K; Ciccosanti CT; Jiang M; Xiao R; Soong TT; Rost B; Acton TB; Everett JK; Pegg AE; Tainer JA; Montelione GT
    J Biol Chem; 2010 Apr; 285(18):13736-41. PubMed ID: 20212037
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Alkylation damage repair protein O6-alkylguanine-DNA alkyltransferase from the hyperthermophiles Aquifex aeolicus and Archaeoglobus fulgidus.
    Kanugula S; Pegg AE
    Biochem J; 2003 Oct; 375(Pt 2):449-55. PubMed ID: 12892560
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Flipping of alkylated DNA damage bridges base and nucleotide excision repair.
    Tubbs JL; Latypov V; Kanugula S; Butt A; Melikishvili M; Kraehenbuehl R; Fleck O; Marriott A; Watson AJ; Verbeek B; McGown G; Thorncroft M; Santibanez-Koref MF; Millington C; Arvai AS; Kroeger MD; Peterson LA; Williams DM; Fried MG; Margison GP; Pegg AE; Tainer JA
    Nature; 2009 Jun; 459(7248):808-13. PubMed ID: 19516334
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Alkylation damage in DNA and RNA--repair mechanisms and medical significance.
    Drabløs F; Feyzi E; Aas PA; Vaagbø CB; Kavli B; Bratlie MS; Peña-Diaz J; Otterlei M; Slupphaug G; Krokan HE
    DNA Repair (Amst); 2004 Nov; 3(11):1389-407. PubMed ID: 15380096
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural basis of interstrand cross-link repair by O
    Denisov AY; McManus FP; O'Flaherty DK; Noronha AM; Wilds CJ
    Org Biomol Chem; 2017 Oct; 15(39):8361-8370. PubMed ID: 28937154
    [TBL] [Abstract][Full Text] [Related]  

  • 13. O(6) -alkylguanine-DNA alkyltransferase-mediated repair of O(4) -alkylated 2'-deoxyuridines.
    McManus FP; Wilds CJ
    Chembiochem; 2014 Sep; 15(13):1966-77. PubMed ID: 25087488
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The DNA Alkylguanine DNA Alkyltransferase-2 (AGT-2) Of Caenorhabditis Elegans Is Involved In Meiosis And Early Development Under Physiological Conditions.
    Serpe M; Forenza C; Adamo A; Russo N; Perugino G; Ciaramella M; Valenti A
    Sci Rep; 2019 May; 9(1):6889. PubMed ID: 31053748
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chemotherapy-induced O(6)-benzylguanine-resistant alkyltransferase mutations in mismatch-deficient colon cancer.
    Liu L; Schwartz S; Davis BM; Gerson SL
    Cancer Res; 2002 Jun; 62(11):3070-6. PubMed ID: 12036916
    [TBL] [Abstract][Full Text] [Related]  

  • 16.
    Mattossovich R; Merlo R; Miggiano R; Valenti A; Perugino G
    Int J Mol Sci; 2020 Apr; 21(8):. PubMed ID: 32326075
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An alkyltransferase-like protein from Thermus thermophilus HB8 affects the regulation of gene expression in alkylation response.
    Morita R; Hishinuma H; Ohyama H; Mega R; Ohta T; Nakagawa N; Agari Y; Fukui K; Shinkai A; Kuramitsu S; Masui R
    J Biochem; 2011 Sep; 150(3):327-39. PubMed ID: 21531768
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inactivation and degradation of O(6)-alkylguanine-DNA alkyltransferase after reaction with nitric oxide.
    Liu L; Xu-Welliver M; Kanugula S; Pegg AE
    Cancer Res; 2002 Jun; 62(11):3037-43. PubMed ID: 12036910
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Brain hypoplasia caused by exposure to trichlorfon and dichlorvos during development can be ascribed to DNA alkylation damage and inhibition of DNA alkyltransferase repair.
    Mehl A; Rolseth V; Gordon S; Bjøraas M; Seeberg E; Fonnum F
    Neurotoxicology; 2000; 21(1-2):165-73. PubMed ID: 10794396
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Alteration of the conserved residue tyrosine-158 to histidine renders human O6-alkylguanine-DNA alkyltransferase insensitive to the inhibitor O6-benzylguanine.
    Xu-Welliver M; Leitão J; Kanugula S; Pegg AE
    Cancer Res; 1999 Apr; 59(7):1514-9. PubMed ID: 10197622
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.