325 related articles for article (PubMed ID: 27783662)
1. MERTK Inhibition Induces Polyploidy and Promotes Cell Death and Cellular Senescence in Glioblastoma Multiforme.
Sufit A; Lee-Sherick AB; DeRyckere D; Rupji M; Dwivedi B; Varella-Garcia M; Pierce AM; Kowalski J; Wang X; Frye SV; Earp HS; Keating AK; Graham DK
PLoS One; 2016; 11(10):e0165107. PubMed ID: 27783662
[TBL] [Abstract][Full Text] [Related]
2. The small-molecule MERTK inhibitor UNC2025 decreases platelet activation and prevents thrombosis.
Branchford BR; Stalker TJ; Law L; Acevedo G; Sather S; Brzezinski C; Wilson KM; Minson K; Lee-Sherick AB; Davizon-Castillo P; Ng C; Zhang W; Neeves KB; Lentz SR; Wang X; Frye SV; Shelton Earp H; DeRyckere D; Brass LF; Graham DK; Di Paola JA
J Thromb Haemost; 2018 Feb; 16(2):352-363. PubMed ID: 29045015
[TBL] [Abstract][Full Text] [Related]
3. Small Molecule Inhibition of MERTK Is Efficacious in Non-Small Cell Lung Cancer Models Independent of Driver Oncogene Status.
Cummings CT; Zhang W; Davies KD; Kirkpatrick GD; Zhang D; DeRyckere D; Wang X; Frye SV; Earp HS; Graham DK
Mol Cancer Ther; 2015 Sep; 14(9):2014-22. PubMed ID: 26162689
[TBL] [Abstract][Full Text] [Related]
4. MerTK as a therapeutic target in glioblastoma.
Wu J; Frady LN; Bash RE; Cohen SM; Schorzman AN; Su YT; Irvin DM; Zamboni WC; Wang X; Frye SV; Ewend MG; Sulman EP; Gilbert MR; Earp HS; Miller CR
Neuro Oncol; 2018 Jan; 20(1):92-102. PubMed ID: 28605477
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of MERTK Promotes Suppression of Tumor Growth in BRAF Mutant and BRAF Wild-Type Melanoma.
Sinik L; Minson KA; Tentler JJ; Carrico J; Bagby SM; Robinson WA; Kami R; Burstyn-Cohen T; Eckhardt SG; Wang X; Frye SV; Earp HS; DeRyckere D; Graham DK
Mol Cancer Ther; 2019 Feb; 18(2):278-288. PubMed ID: 30482852
[TBL] [Abstract][Full Text] [Related]
6. MerTK inhibition is a novel therapeutic approach for glioblastoma multiforme.
Knubel KH; Pernu BM; Sufit A; Nelson S; Pierce AM; Keating AK
Oncotarget; 2014 Mar; 5(5):1338-51. PubMed ID: 24658326
[TBL] [Abstract][Full Text] [Related]
7. MerTK activity is not necessary for the proliferation of glioblastoma stem cells.
Hoque M; Wai Wong S; Recasens A; Abbassi R; Nguyen N; Zhang D; Stashko MA; Wang X; Frye S; Day BW; Baell J; Munoz L
Biochem Pharmacol; 2021 Apr; 186():114437. PubMed ID: 33571503
[TBL] [Abstract][Full Text] [Related]
8. UNC2025, a MERTK Small-Molecule Inhibitor, Is Therapeutically Effective Alone and in Combination with Methotrexate in Leukemia Models.
DeRyckere D; Lee-Sherick AB; Huey MG; Hill AA; Tyner JW; Jacobsen KM; Page LS; Kirkpatrick GG; Eryildiz F; Montgomery SA; Zhang W; Wang X; Frye SV; Earp HS; Graham DK
Clin Cancer Res; 2017 Mar; 23(6):1481-1492. PubMed ID: 27649555
[No Abstract] [Full Text] [Related]
9. MERTK receptor tyrosine kinase is a therapeutic target in melanoma.
Schlegel J; Sambade MJ; Sather S; Moschos SJ; Tan AC; Winges A; DeRyckere D; Carson CC; Trembath DG; Tentler JJ; Eckhardt SG; Kuan PF; Hamilton RL; Duncan LM; Miller CR; Nikolaishvili-Feinberg N; Midkiff BR; Liu J; Zhang W; Yang C; Wang X; Frye SV; Earp HS; Shields JM; Graham DK
J Clin Invest; 2013 May; 123(5):2257-67. PubMed ID: 23585477
[TBL] [Abstract][Full Text] [Related]
10. MerTK mediates STAT3-KRAS/SRC-signaling axis for glioma stem cell maintenance.
Eom H; Kaushik N; Yoo KC; Shim JK; Kwon M; Choi MY; Yoon T; Kang SG; Lee SJ
Artif Cells Nanomed Biotechnol; 2018; 46(sup2):87-95. PubMed ID: 29553850
[TBL] [Abstract][Full Text] [Related]
11. Mer receptor tyrosine kinase inhibition impedes glioblastoma multiforme migration and alters cellular morphology.
Rogers AE; Le JP; Sather S; Pernu BM; Graham DK; Pierce AM; Keating AK
Oncogene; 2012 Sep; 31(38):4171-81. PubMed ID: 22179835
[TBL] [Abstract][Full Text] [Related]
12. Small molecule inhibition of Axl receptor tyrosine kinase potently suppresses multiple malignant properties of glioma cells.
Vouri M; An Q; Birt M; Pilkington GJ; Hafizi S
Oncotarget; 2015 Jun; 6(18):16183-97. PubMed ID: 25980499
[TBL] [Abstract][Full Text] [Related]
13. Mer receptor tyrosine kinase promotes invasion and survival in glioblastoma multiforme.
Wang Y; Moncayo G; Morin P; Xue G; Grzmil M; Lino MM; Clément-Schatlo V; Frank S; Merlo A; Hemmings BA
Oncogene; 2013 Feb; 32(7):872-82. PubMed ID: 22469987
[TBL] [Abstract][Full Text] [Related]
14. Small molecule inhibitors block Gas6-inducible TAM activation and tumorigenicity.
Kimani SG; Kumar S; Bansal N; Singh K; Kholodovych V; Comollo T; Peng Y; Kotenko SV; Sarafianos SG; Bertino JR; Welsh WJ; Birge RB
Sci Rep; 2017 Mar; 7():43908. PubMed ID: 28272423
[TBL] [Abstract][Full Text] [Related]
15. 2-(2-(2,4-dioxopentan-3-ylidene)hydrazineyl)benzonitrile as novel inhibitor of receptor tyrosine kinase and PI3K/AKT/mTOR signaling pathway in glioblastoma.
Viswanathan A; Kute D; Musa A; Konda Mani S; Sipilä V; Emmert-Streib F; Zubkov FI; Gurbanov AV; Yli-Harja O; Kandhavelu M
Eur J Med Chem; 2019 Mar; 166():291-303. PubMed ID: 30731398
[TBL] [Abstract][Full Text] [Related]
16. Silencing of PROS1 induces apoptosis and inhibits migration and invasion of glioblastoma multiforme cells.
Che Mat MF; Abdul Murad NA; Ibrahim K; Mohd Mokhtar N; Wan Ngah WZ; Harun R; Jamal R
Int J Oncol; 2016 Dec; 49(6):2359-2366. PubMed ID: 27840905
[TBL] [Abstract][Full Text] [Related]
17. Molecular pathways: MERTK signaling in cancer.
Cummings CT; Deryckere D; Earp HS; Graham DK
Clin Cancer Res; 2013 Oct; 19(19):5275-80. PubMed ID: 23833304
[TBL] [Abstract][Full Text] [Related]
18. MERTK Mediates Intrinsic and Adaptive Resistance to AXL-targeting Agents.
McDaniel NK; Cummings CT; Iida M; Hülse J; Pearson HE; Vasileiadi E; Parker RE; Orbuch RA; Ondracek OJ; Welke NB; Kang GH; Davies KD; Wang X; Frye SV; Earp HS; Harari PM; Kimple RJ; DeRyckere D; Graham DK; Wheeler DL
Mol Cancer Ther; 2018 Nov; 17(11):2297-2308. PubMed ID: 30093568
[TBL] [Abstract][Full Text] [Related]
19. Modulation of protein S and growth arrest specific 6 protein signaling inhibits pancreatic cancer cell survival and proliferation.
Pilli VS; Datta A; Dorsey A; Liu B; Majumder R
Oncol Rep; 2020 Oct; 44(4):1322-1332. PubMed ID: 32945517
[TBL] [Abstract][Full Text] [Related]
20. Matrine induces senescence of human glioblastoma cells through suppression of the IGF1/PI3K/AKT/p27 signaling pathway.
Zhou W; Wang J; Qi Q; Feng Z; Huang B; Chen A; Zhang D; Li W; Zhang Q; Bjerkvig R; Li X; Wang J
Cancer Med; 2018 Sep; 7(9):4729-4743. PubMed ID: 30079478
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]