369 related articles for article (PubMed ID: 27783974)
1. Synthesis of new donepezil analogues and investigation of their effects on cholinesterase enzymes.
Sağlık BN; Ilgın S; Özkay Y
Eur J Med Chem; 2016 Nov; 124():1026-1040. PubMed ID: 27783974
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and evaluation of multi-target-directed ligands against Alzheimer's disease based on the fusion of donepezil and ebselen.
Luo Z; Sheng J; Sun Y; Lu C; Yan J; Liu A; Luo HB; Huang L; Li X
J Med Chem; 2013 Nov; 56(22):9089-99. PubMed ID: 24160297
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis, and AChE inhibitory activity of new benzothiazole-piperazines.
Demir Özkay Ü; Can ÖD; Sağlık BN; Acar Çevik U; Levent S; Özkay Y; Ilgın S; Atlı Ö
Bioorg Med Chem Lett; 2016 Nov; 26(22):5387-5394. PubMed ID: 27789142
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and biological activity of new donepezil-hydrazinonicotinamide hybrids.
Zurek E; Szymański P; Mikiciuk-Olasik E
Drug Res (Stuttg); 2013 Mar; 63(3):137-44. PubMed ID: 23447117
[TBL] [Abstract][Full Text] [Related]
5. Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.
Bolea I; Juárez-Jiménez J; de Los Ríos C; Chioua M; Pouplana R; Luque FJ; Unzeta M; Marco-Contelles J; Samadi A
J Med Chem; 2011 Dec; 54(24):8251-70. PubMed ID: 22023459
[TBL] [Abstract][Full Text] [Related]
6. Acetylcholinesterase inhibitors: structure based design, synthesis, pharmacophore modeling, and virtual screening.
Valasani KR; Chaney MO; Day VW; Shidu Yan S
J Chem Inf Model; 2013 Aug; 53(8):2033-46. PubMed ID: 23777291
[TBL] [Abstract][Full Text] [Related]
7. New piperidine-hydrazone derivatives: Synthesis, biological evaluations and molecular docking studies as AChE and BChE inhibitors.
Karaman N; Sıcak Y; Taşkın-Tok T; Öztürk M; Karaküçük-İyidoğan A; Dikmen M; Koçyiğit-Kaymakçıoğlu B; Oruç-Emre EE
Eur J Med Chem; 2016 Nov; 124():270-283. PubMed ID: 27592396
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and pharmacological evaluation of donepezil-based agents as new cholinesterase/monoamine oxidase inhibitors for the potential application against Alzheimer's disease.
Li F; Wang ZM; Wu JJ; Wang J; Xie SS; Lan JS; Xu W; Kong LY; Wang XB
J Enzyme Inhib Med Chem; 2016; 31(sup3):41-53. PubMed ID: 27384289
[TBL] [Abstract][Full Text] [Related]
9. Novel donepezil-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation.
Camps P; Formosa X; Galdeano C; Gómez T; Muñoz-Torrero D; Scarpellini M; Viayna E; Badia A; Clos MV; Camins A; Pallàs M; Bartolini M; Mancini F; Andrisano V; Estelrich J; Lizondo M; Bidon-Chanal A; Luque FJ
J Med Chem; 2008 Jun; 51(12):3588-98. PubMed ID: 18517184
[TBL] [Abstract][Full Text] [Related]
10. Kinetic and structural studies on the interactions of Torpedo californica acetylcholinesterase with two donepezil-like rigid analogues.
Caliandro R; Pesaresi A; Cariati L; Procopio A; Oliverio M; Lamba D
J Enzyme Inhib Med Chem; 2018 Dec; 33(1):794-803. PubMed ID: 29651884
[TBL] [Abstract][Full Text] [Related]
11. 7-MEOTA-donepezil like compounds as cholinesterase inhibitors: Synthesis, pharmacological evaluation, molecular modeling and QSAR studies.
Korabecny J; Dolezal R; Cabelova P; Horova A; Hruba E; Ricny J; Sedlacek L; Nepovimova E; Spilovska K; Andrs M; Musilek K; Opletalova V; Sepsova V; Ripova D; Kuca K
Eur J Med Chem; 2014 Jul; 82():426-38. PubMed ID: 24929293
[TBL] [Abstract][Full Text] [Related]
12. Rational modification of donepezil as multifunctional acetylcholinesterase inhibitors for the treatment of Alzheimer's disease.
Wang ZM; Cai P; Liu QH; Xu DQ; Yang XL; Wu JJ; Kong LY; Wang XB
Eur J Med Chem; 2016 Nov; 123():282-297. PubMed ID: 27484514
[TBL] [Abstract][Full Text] [Related]
13. Design, synthesis and biological activity of novel donepezil derivatives bearing N-benzyl pyridinium moiety as potent and dual binding site acetylcholinesterase inhibitors.
Lan JS; Zhang T; Liu Y; Yang J; Xie SS; Liu J; Miao ZY; Ding Y
Eur J Med Chem; 2017 Jun; 133():184-196. PubMed ID: 28388521
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and biological evaluation as AChE inhibitors of new indanones and thiaindanones related to donepezil.
Omran Z; Cailly T; Lescot E; Santos JS; Agondanou JH; Lisowski V; Fabis F; Godard AM; Stiebing S; Le Flem G; Boulouard M; Dauphin F; Dallemagne P; Rault S
Eur J Med Chem; 2005 Dec; 40(12):1222-45. PubMed ID: 16137794
[TBL] [Abstract][Full Text] [Related]
15. Hybridization-based design of novel anticholinesterase indanone-carbamates for Alzheimer's disease: Synthesis, biological evaluation, and docking studies.
Shahrivar-Gargari M; Hamzeh-Mivehroud M; Hemmati S; Mojarrad JS; Tüylü Küçükkılınç T; Ayazgök B; Dastmalchi S
Arch Pharm (Weinheim); 2021 Jul; 354(7):e2000453. PubMed ID: 33872422
[TBL] [Abstract][Full Text] [Related]
16. Aromatic amino-acid residues at the active and peripheral anionic sites control the binding of E2020 (Aricept) to cholinesterases.
Saxena A; Fedorko JM; Vinayaka CR; Medhekar R; Radić Z; Taylor P; Lockridge O; Doctor BP
Eur J Biochem; 2003 Nov; 270(22):4447-58. PubMed ID: 14622273
[TBL] [Abstract][Full Text] [Related]
17. Synthesis, in vitro assay, and molecular modeling of new piperidine derivatives having dual inhibitory potency against acetylcholinesterase and Abeta1-42 aggregation for Alzheimer's disease therapeutics.
Kwon YE; Park JY; No KT; Shin JH; Lee SK; Eun JS; Yang JH; Shin TY; Kim DK; Chae BS; Leem JY; Kim KH
Bioorg Med Chem; 2007 Oct; 15(20):6596-607. PubMed ID: 17681794
[TBL] [Abstract][Full Text] [Related]
18. Targeting Alzheimer's disease by investigating previously unexplored chemical space surrounding the cholinesterase inhibitor donepezil.
van Greunen DG; Cordier W; Nell M; van der Westhuyzen C; Steenkamp V; Panayides JL; Riley DL
Eur J Med Chem; 2017 Feb; 127():671-690. PubMed ID: 27823887
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis and evaluation of novel heterodimers of donepezil and huperzine fragments as acetylcholinesterase inhibitors.
Hu Y; Zhang J; Chandrashankra O; Ip FC; Ip NY
Bioorg Med Chem; 2013 Feb; 21(3):676-83. PubMed ID: 23273608
[TBL] [Abstract][Full Text] [Related]
20. Design and synthesis of some new carboxamide and propanamide derivatives bearing phenylpyridazine as a core ring and the investigation of their inhibitory potential on in-vitro acetylcholinesterase and butyrylcholinesterase.
Kilic B; Gulcan HO; Aksakal F; Ercetin T; Oruklu N; Umit Bagriacik E; Dogruer DS
Bioorg Chem; 2018 Sep; 79():235-249. PubMed ID: 29775949
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]