114 related articles for article (PubMed ID: 27793568)
21. Synthesis of novel taspine diphenyl derivatives as fluorescence probes and inhibitors of breast cancer cell proliferation.
He H; Zhan Y; Zhang Y; Zhang J; He L
Luminescence; 2012; 27(4):310-4. PubMed ID: 21755586
[TBL] [Abstract][Full Text] [Related]
22. Discovery of tetrahydro-beta-carbolines as inhibitors of the mitotic kinesin KSP.
Liu F; Yu LQ; Jiang C; Yang L; Wu WT; You QD
Bioorg Med Chem; 2010 Jun; 18(12):4167-77. PubMed ID: 20537544
[TBL] [Abstract][Full Text] [Related]
23. Synthesis and SAR of thiophene containing kinesin spindle protein (KSP) inhibitors.
Pinkerton AB; Lee TT; Hoffman TZ; Wang Y; Kahraman M; Cook TG; Severance D; Gahman TC; Noble SA; Shiau AK; Davis RL
Bioorg Med Chem Lett; 2007 Jul; 17(13):3562-9. PubMed ID: 17498954
[TBL] [Abstract][Full Text] [Related]
24. Conformation-dependent ligand regulation of ATP hydrolysis by human KSP: activation of basal hydrolysis and inhibition of microtubule-stimulated hydrolysis by a single, small molecule modulator.
Luo L; Carson JD; Molnar KS; Tuske SJ; Coales SJ; Hamuro Y; Sung CM; Sudakin V; Auger KR; Dhanak D; Jackson JR; Huang PS; Tummino PJ; Copeland RA
J Am Chem Soc; 2008 Jun; 130(24):7584-91. PubMed ID: 18491908
[TBL] [Abstract][Full Text] [Related]
25. Recent progress in the identification and clinical evaluation of inhibitors of the mitotic kinesin KSP.
Knight SD; Parrish CA
Curr Top Med Chem; 2008; 8(10):888-904. PubMed ID: 18673173
[TBL] [Abstract][Full Text] [Related]
26. An inhibitor of the kinesin spindle protein activates the intrinsic apoptotic pathway independently of p53 and de novo protein synthesis.
Tao W; South VJ; Diehl RE; Davide JP; Sepp-Lorenzino L; Fraley ME; Arrington KL; Lobell RB
Mol Cell Biol; 2007 Jan; 27(2):689-98. PubMed ID: 17101792
[TBL] [Abstract][Full Text] [Related]
27. Kinesin spindle protein (KSP) inhibitors. Part 7: Design and synthesis of 3,3-disubstituted dihydropyrazolobenzoxazines as potent inhibitors of the mitotic kinesin KSP.
Garbaccio RM; Tasber ES; Neilson LA; Coleman PJ; Fraley ME; Olson C; Bergman J; Torrent M; Buser CA; Rickert K; Walsh ES; Hamilton K; Lobell RB; Tao W; South VJ; Diehl RE; Davide JP; Yan Y; Kuo LC; Li C; Prueksaritanont T; Fernandez-Metzler C; Mahan EA; Slaughter DE; Salata JJ; Kohl NE; Huber HE; Hartman GD
Bioorg Med Chem Lett; 2007 Oct; 17(20):5671-6. PubMed ID: 17804233
[TBL] [Abstract][Full Text] [Related]
28. Optimization of diaryl amine derivatives as kinesin spindle protein inhibitors.
Takeuchi T; Oishi S; Kaneda M; Misu R; Ohno H; Sawada J; Asai A; Nakamura S; Nakanishi I; Fujii N
Bioorg Med Chem; 2014 Jun; 22(12):3171-9. PubMed ID: 24794744
[TBL] [Abstract][Full Text] [Related]
29. Discovery and biochemical characterization of selective ATP competitive inhibitors of the human mitotic kinesin KSP.
Rickert KW; Schaber M; Torrent M; Neilson LA; Tasber ES; Garbaccio R; Coleman PJ; Harvey D; Zhang Y; Yang Y; Marshall G; Lee L; Walsh ES; Hamilton K; Buser CA
Arch Biochem Biophys; 2008 Jan; 469(2):220-31. PubMed ID: 17999913
[TBL] [Abstract][Full Text] [Related]
30. Kinesin spindle protein inhibitors in cancer: a patent review (2008 - present).
Jiang C; You Q
Expert Opin Ther Pat; 2013 Dec; 23(12):1547-60. PubMed ID: 23978071
[TBL] [Abstract][Full Text] [Related]
31. 1,3a,6a-Triazapentalene derivatives as photo-induced cytotoxic small fluorescent dyes.
Tsuji D; Nakayama A; Yamamoto R; Nagano S; Taniguchi T; Sato R; Karanjit S; Muguruma N; Takayama T; Itoh K; Namba K
Commun Chem; 2023 Feb; 6(1):37. PubMed ID: 36813913
[TBL] [Abstract][Full Text] [Related]
32. A tryptophan-containing fluorescent intramolecular complex as a designer peptidic proton sensor.
Haridas V; Yadav A; Sharma S; Pandey S
Phys Chem Chem Phys; 2016 Jun; 18(22):15046-53. PubMed ID: 27194411
[TBL] [Abstract][Full Text] [Related]
33. Novel benzimidazole inhibitors bind to a unique site in the kinesin spindle protein motor domain.
Sheth PR; Shipps GW; Seghezzi W; Smith CK; Chuang CC; Sanden D; Basso AD; Vilenchik L; Gray K; Annis DA; Nickbarg E; Ma Y; Lahue B; Herbst R; Le HV
Biochemistry; 2010 Sep; 49(38):8350-8. PubMed ID: 20718440
[TBL] [Abstract][Full Text] [Related]
34. Structure-based design of new KSP-Eg5 inhibitors assisted by a targeted multicomponent reaction.
Carbajales C; Prado MÁ; Gutiérrez-de-Terán H; Cores A; Azuaje J; Novio S; Nuñez MJ; Fernández-García B; Sotelo E; García-Mera X; Sánchez-Lazo P; Freire-Garabal M; Coelho A
Chembiochem; 2014 Jul; 15(10):1471-80. PubMed ID: 24943831
[TBL] [Abstract][Full Text] [Related]
35. Kinesin spindle protein (KSP) inhibitors. Part V: discovery of 2-propylamino-2,4-diaryl-2,5-dihydropyrroles as potent, water-soluble KSP inhibitors, and modulation of their basicity by beta-fluorination to overcome cellular efflux by P-glycoprotein.
Cox CD; Breslin MJ; Whitman DB; Coleman PJ; Garbaccio RM; Fraley ME; Zrada MM; Buser CA; Walsh ES; Hamilton K; Lobell RB; Tao W; Abrams MT; South VJ; Huber HE; Kohl NE; Hartman GD
Bioorg Med Chem Lett; 2007 May; 17(10):2697-702. PubMed ID: 17395460
[TBL] [Abstract][Full Text] [Related]
36. CPUYJ039, a newly synthesized benzimidazole-based compound, is proved to be a novel inducer of apoptosis in HCT116 cells with potent KSP inhibitory activity.
Jiang C; Yang L; Wu WT; Guo QL; You QD
J Pharm Pharmacol; 2011 Nov; 63(11):1462-9. PubMed ID: 21988427
[TBL] [Abstract][Full Text] [Related]
37. Fluorinated quinazolinones as potential radiotracers for imaging kinesin spindle protein expression.
Holland JP; Jones MW; Cohrs S; Schibli R; Fischer E
Bioorg Med Chem; 2013 Jan; 21(2):496-507. PubMed ID: 23245569
[TBL] [Abstract][Full Text] [Related]
38. Kinesin spindle protein (KSP) inhibitors. Part 4: Structure-based design of 5-alkylamino-3,5-diaryl-4,5-dihydropyrazoles as potent, water-soluble inhibitors of the mitotic kinesin KSP.
Cox CD; Torrent M; Breslin MJ; Mariano BJ; Whitman DB; Coleman PJ; Buser CA; Walsh ES; Hamilton K; Schaber MD; Lobell RB; Tao W; South VJ; Kohl NE; Yan Y; Kuo LC; Prueksaritanont T; Slaughter DE; Li C; Mahan E; Lu B; Hartman GD
Bioorg Med Chem Lett; 2006 Jun; 16(12):3175-9. PubMed ID: 16603356
[TBL] [Abstract][Full Text] [Related]
39. Development of a 1,3a,6a-triazapentalene derivative as a compact and thiol-specific fluorescent labeling reagent.
Nakayama A; Otani A; Inokuma T; Tsuji D; Mukaiyama H; Nakayama A; Itoh K; Otaka A; Tanino K; Namba K
Commun Chem; 2020 Jan; 3(1):6. PubMed ID: 36703318
[TBL] [Abstract][Full Text] [Related]
40. Kinesin spindle protein (KSP) inhibitors. Part 6: Design and synthesis of 3,5-diaryl-4,5-dihydropyrazole amides as potent inhibitors of the mitotic kinesin KSP.
Coleman PJ; Schreier JD; Cox CD; Fraley ME; Garbaccio RM; Buser CA; Walsh ES; Hamilton K; Lobell RB; Rickert K; Tao W; Diehl RE; South VJ; Davide JP; Kohl NE; Yan Y; Kuo L; Prueksaritanont T; Li C; Mahan EA; Fernandez-Metzler C; Salata JJ; Hartman GD
Bioorg Med Chem Lett; 2007 Oct; 17(19):5390-5. PubMed ID: 17761419
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
