These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 27794454)

  • 1. Characterization of aminoacyl-tRNA synthetase stability and substrate interaction by differential scanning fluorimetry.
    Abbott JA; Livingston NM; Egri SB; Guth E; Francklyn CS
    Methods; 2017 Jan; 113():64-71. PubMed ID: 27794454
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A substrate-assisted concerted mechanism for aminoacylation by a class II aminoacyl-tRNA synthetase.
    Guth E; Connolly SH; Bovee M; Francklyn CS
    Biochemistry; 2005 Mar; 44(10):3785-94. PubMed ID: 15751955
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting tRNA-synthetase interactions towards novel therapeutic discovery against eukaryotic pathogens.
    Kelly P; Hadi-Nezhad F; Liu DY; Lawrence TJ; Linington RG; Ibba M; Ardell DH
    PLoS Negl Trop Dis; 2020 Feb; 14(2):e0007983. PubMed ID: 32106219
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dynamics of the active site loops in catalyzing aminoacylation reaction in seryl and histidyl tRNA synthetases.
    Dutta S; Kundu S; Saha A; Nandi N
    J Biomol Struct Dyn; 2018 Mar; 36(4):878-892. PubMed ID: 28317434
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Fine-Tuning of Alanyl-tRNA Synthetase Quality Control Alleviates Global Dysregulation of the Proteome.
    Kelly P; Kavoor A; Ibba M
    Genes (Basel); 2020 Oct; 11(10):. PubMed ID: 33081015
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RNA-assisted catalysis in a protein enzyme: The 2'-hydroxyl of tRNA(Thr) A76 promotes aminoacylation by threonyl-tRNA synthetase.
    Minajigi A; Francklyn CS
    Proc Natl Acad Sci U S A; 2008 Nov; 105(46):17748-53. PubMed ID: 18997014
    [TBL] [Abstract][Full Text] [Related]  

  • 7. G-1:C73 recognition by an arginine cluster in the active site of Escherichia coli histidyl-tRNA synthetase.
    Connolly SA; Rosen AE; Musier-Forsyth K; Francklyn CS
    Biochemistry; 2004 Feb; 43(4):962-9. PubMed ID: 14744140
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Covariation of a specificity-determining structural motif in an aminoacyl-tRNA synthetase and a tRNA identity element.
    Hawko SA; Francklyn CS
    Biochemistry; 2001 Feb; 40(7):1930-6. PubMed ID: 11329259
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Histidyl-tRNA synthetase.
    Freist W; Verhey JF; Rühlmann A; Gauss DH; Arnez JG
    Biol Chem; 1999 Jun; 380(6):623-46. PubMed ID: 10430027
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Asymmetric amino acid activation by class II histidyl-tRNA synthetase from Escherichia coli.
    Guth E; Farris M; Bovee M; Francklyn CS
    J Biol Chem; 2009 Jul; 284(31):20753-62. PubMed ID: 19487703
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Substrate interaction defects in histidyl-tRNA synthetase linked to dominant axonal peripheral neuropathy.
    Abbott JA; Meyer-Schuman R; Lupo V; Feely S; Mademan I; Oprescu SN; Griffin LB; Alberti MA; Casasnovas C; Aharoni S; Basel-Vanagaite L; Züchner S; De Jonghe P; Baets J; Shy ME; Espinós C; Demeler B; Antonellis A; Francklyn C
    Hum Mutat; 2018 Mar; 39(3):415-432. PubMed ID: 29235198
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthetic and editing reactions of aminoacyl-tRNA synthetases using cognate and non-cognate amino acid substrates.
    Cvetesic N; Gruic-Sovulj I
    Methods; 2017 Jan; 113():13-26. PubMed ID: 27713080
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Substrate specificity and catalysis by the editing active site of Alanyl-tRNA synthetase from Escherichia coli.
    Pasman Z; Robey-Bond S; Mirando AC; Smith GJ; Lague A; Francklyn CS
    Biochemistry; 2011 Mar; 50(9):1474-82. PubMed ID: 21241052
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A Human Disease-causing Point Mutation in Mitochondrial Threonyl-tRNA Synthetase Induces Both Structural and Functional Defects.
    Wang Y; Zhou XL; Ruan ZR; Liu RJ; Eriani G; Wang ED
    J Biol Chem; 2016 Mar; 291(12):6507-20. PubMed ID: 26811336
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evidence for a "cysteine-histidine box" metal-binding site in an Escherichia coli aminoacyl-tRNA synthetase.
    Miller WT; Hill KA; Schimmel P
    Biochemistry; 1991 Jul; 30(28):6970-6. PubMed ID: 1712632
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Allosteric interaction of nucleotides and tRNA(ala) with E. coli alanyl-tRNA synthetase.
    Dignam JD; Guo J; Griffith WP; Garbett NC; Holloway A; Mueser T
    Biochemistry; 2011 Nov; 50(45):9886-900. PubMed ID: 21985608
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Histidyl-tRNA synthetase urzymes: Class I and II aminoacyl tRNA synthetase urzymes have comparable catalytic activities for cognate amino acid activation.
    Li L; Weinreb V; Francklyn C; Carter CW
    J Biol Chem; 2011 Mar; 286(12):10387-95. PubMed ID: 21270472
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A succession of substrate induced conformational changes ensures the amino acid specificity of Thermus thermophilus prolyl-tRNA synthetase: comparison with histidyl-tRNA synthetase.
    Yaremchuk A; Tukalo M; Grøtli M; Cusack S
    J Mol Biol; 2001 Jun; 309(4):989-1002. PubMed ID: 11399074
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase.
    Fang P; Yu X; Jeong SJ; Mirando A; Chen K; Chen X; Kim S; Francklyn CS; Guo M
    Nat Commun; 2015 Mar; 6():6402. PubMed ID: 25824639
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Kinetic discrimination of tRNA identity by the conserved motif 2 loop of a class II aminoacyl-tRNA synthetase.
    Guth EC; Francklyn CS
    Mol Cell; 2007 Feb; 25(4):531-42. PubMed ID: 17317626
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.