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BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

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  • 11. Evaluation of the XRCC1 gene as a phenotypic modifier in BRCA1/2 mutation carriers. Results from the consortium of investigators of modifiers of BRCA1/BRCA2.
    Osorio A; Milne RL; Alonso R; Pita G; Peterlongo P; Teulé A; Nathanson KL; Domchek SM; Rebbeck T; Lasa A; Konstantopoulou I; Hogervorst FB; Verhoef S; van Dooren MF; Jager A; Ausems MG; Aalfs CM; van Asperen CJ; Vreeswijk M; Waisfisz Q; Van Roozendaal CE; Ligtenberg MJ; ; ; Easton DF; Peock S; Cook M; Oliver CT; Frost D; Curzon B; Evans DG; Lalloo F; Eeles R; Izatt L; Davidson R; Adlard J; Eccles D; Ong KR; Douglas F; Downing S; Brewer C; Walker L; Nevanlinna H; Aittomäki K; Couch FJ; Fredericksen Z; Lindor NM; Godwin A; Isaacs C; Caligo MA; Loman N; Jernström H; Barbany-Bustinza G; Liljegren A; Ehrencrona H; Stenmark-Askmalm M; ; Feliubadaló L; Manoukian S; Peissel B; Zaffaroni D; Bonanni B; Fortuzzi S; Johannsson OT; Chenevix-Trench G; Chen XC; Beesley J; Spurdle AB; ; Sinilnikova OM; Healey S; McGuffog L; Antoniou AC; Brunet J; Radice P; Benítez J;
    Br J Cancer; 2011 Apr; 104(8):1356-61. PubMed ID: 21427728
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  • 12. Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers.
    Kuchenbaecker KB; McGuffog L; Barrowdale D; Lee A; Soucy P; Dennis J; Domchek SM; Robson M; Spurdle AB; Ramus SJ; Mavaddat N; Terry MB; Neuhausen SL; Schmutzler RK; Simard J; Pharoah PDP; Offit K; Couch FJ; Chenevix-Trench G; Easton DF; Antoniou AC
    J Natl Cancer Inst; 2017 Jul; 109(7):. PubMed ID: 28376175
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  • 13. Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers.
    Antoniou AC; Spurdle AB; Sinilnikova OM; Healey S; Pooley KA; Schmutzler RK; Versmold B; Engel C; Meindl A; Arnold N; Hofmann W; Sutter C; Niederacher D; Deissler H; Caldes T; Kämpjärvi K; Nevanlinna H; Simard J; Beesley J; Chen X; ; Neuhausen SL; Rebbeck TR; Wagner T; Lynch HT; Isaacs C; Weitzel J; Ganz PA; Daly MB; Tomlinson G; Olopade OI; Blum JL; Couch FJ; Peterlongo P; Manoukian S; Barile M; Radice P; Szabo CI; Pereira LH; Greene MH; Rennert G; Lejbkowicz F; Barnett-Griness O; Andrulis IL; Ozcelik H; ; Gerdes AM; Caligo MA; Laitman Y; Kaufman B; Milgrom R; Friedman E; ; Domchek SM; Nathanson KL; Osorio A; Llort G; Milne RL; Benítez J; Hamann U; Hogervorst FB; Manders P; Ligtenberg MJ; van den Ouweland AM; ; Peock S; Cook M; Platte R; Evans DG; Eeles R; Pichert G; Chu C; Eccles D; Davidson R; Douglas F; ; Godwin AK; Barjhoux L; Mazoyer S; Sobol H; Bourdon V; Eisinger F; Chompret A; Capoulade C; Bressac-de Paillerets B; Lenoir GM; Gauthier-Villars M; Houdayer C; Stoppa-Lyonnet D; ; Chenevix-Trench G; Easton DF;
    Am J Hum Genet; 2008 Apr; 82(4):937-48. PubMed ID: 18355772
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  • 14. Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA).
    Mavaddat N; Barrowdale D; Andrulis IL; Domchek SM; Eccles D; Nevanlinna H; Ramus SJ; Spurdle A; Robson M; Sherman M; Mulligan AM; Couch FJ; Engel C; McGuffog L; Healey S; Sinilnikova OM; Southey MC; Terry MB; Goldgar D; O'Malley F; John EM; Janavicius R; Tihomirova L; Hansen TV; Nielsen FC; Osorio A; Stavropoulou A; Benítez J; Manoukian S; Peissel B; Barile M; Volorio S; Pasini B; Dolcetti R; Putignano AL; Ottini L; Radice P; Hamann U; Rashid MU; Hogervorst FB; Kriege M; van der Luijt RB; ; Peock S; Frost D; Evans DG; Brewer C; Walker L; Rogers MT; Side LE; Houghton C; ; Weaver J; Godwin AK; Schmutzler RK; Wappenschmidt B; Meindl A; Kast K; Arnold N; Niederacher D; Sutter C; Deissler H; Gadzicki D; Preisler-Adams S; Varon-Mateeva R; Schönbuchner I; Gevensleben H; Stoppa-Lyonnet D; Belotti M; Barjhoux L; ; Isaacs C; Peshkin BN; Caldes T; de la Hoya M; Cañadas C; Heikkinen T; Heikkilä P; Aittomäki K; Blanco I; Lazaro C; Brunet J; Agnarsson BA; Arason A; Barkardottir RB; Dumont M; Simard J; Montagna M; Agata S; D'Andrea E; Yan M; Fox S; ; Rebbeck TR; Rubinstein W; Tung N; Garber JE; Wang X; Fredericksen Z; Pankratz VS; Lindor NM; Szabo C; Offit K; Sakr R; Gaudet MM; Singer CF; Tea MK; Rappaport C; Mai PL; Greene MH; Sokolenko A; Imyanitov E; Toland AE; Senter L; Sweet K; Thomassen M; Gerdes AM; Kruse T; Caligo M; Aretini P; Rantala J; von Wachenfeld A; Henriksson K; ; Steele L; Neuhausen SL; Nussbaum R; Beattie M; Odunsi K; Sucheston L; Gayther SA; Nathanson K; Gross J; Walsh C; Karlan B; Chenevix-Trench G; Easton DF; Antoniou AC;
    Cancer Epidemiol Biomarkers Prev; 2012 Jan; 21(1):134-47. PubMed ID: 22144499
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  • 15. Evidence for SMAD3 as a modifier of breast cancer risk in BRCA2 mutation carriers.
    Walker LC; Fredericksen ZS; Wang X; Tarrell R; Pankratz VS; Lindor NM; Beesley J; Healey S; Chen X; ; Stoppa-Lyonnet D; Tirapo C; Giraud S; Mazoyer S; Muller D; Fricker JP; Delnatte C; ; Schmutzler RK; Wappenschmidt B; Engel C; Schönbuchner I; Deissler H; Meindl A; Hogervorst FB; Verheus M; Hooning MJ; van den Ouweland AM; Nelen MR; Ausems MG; Aalfs CM; van Asperen CJ; Devilee P; Gerrits MM; Waisfisz Q; ; Szabo CI; ; Easton DF; Peock S; Cook M; Oliver CT; Frost D; Harrington P; Evans DG; Lalloo F; Eeles R; Izatt L; Chu C; Davidson R; Eccles D; Ong KR; Cook J; ; Rebbeck T; Nathanson KL; Domchek SM; Singer CF; Gschwantler-Kaulich D; Dressler AC; Pfeiler G; Godwin AK; Heikkinen T; Nevanlinna H; Agnarsson BA; Caligo MA; Olsson H; Kristoffersson U; Liljegren A; Arver B; Karlsson P; Melin B; ; Sinilnikova OM; McGuffog L; Antoniou AC; Chenevix-Trench G; Spurdle AB; Couch FJ
    Breast Cancer Res; 2010; 12(6):R102. PubMed ID: 21114847
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  • 16. Use of expression data and the CGEMS genome-wide breast cancer association study to identify genes that may modify risk in BRCA1/2 mutation carriers.
    Walker LC; Waddell N; Ten Haaf A; ; Grimmond S; Spurdle AB
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  • 17. The TP53 Arg72Pro and MDM2 309G>T polymorphisms are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers.
    Sinilnikova OM; Antoniou AC; Simard J; Healey S; Léoné M; Sinnett D; Spurdle AB; Beesley J; Chen X; ; Greene MH; Loud JT; Lejbkowicz F; Rennert G; Dishon S; Andrulis IL; ; Domchek SM; Nathanson KL; Manoukian S; Radice P; Konstantopoulou I; Blanco I; Laborde AL; Durán M; Osorio A; Benitez J; Hamann U; Hogervorst FB; van Os TA; Gille HJ; ; Peock S; Cook M; Luccarini C; Evans DG; Lalloo F; Eeles R; Pichert G; Davidson R; Cole T; Cook J; Paterson J; Brewer C; ; Hughes DJ; Coupier I; Giraud S; Coulet F; Colas C; Soubrier F; Rouleau E; Bièche I; Lidereau R; Demange L; Nogues C; Lynch HT; ; Schmutzler RK; Versmold B; Engel C; Meindl A; Arnold N; Sutter C; Deissler H; Schaefer D; Froster UG; ; Aittomäki K; Nevanlinna H; McGuffog L; Easton DF; Chenevix-Trench G; Stoppa-Lyonnet D;
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  • 18. Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers.
    Antoniou AC; Sinilnikova OM; McGuffog L; Healey S; Nevanlinna H; Heikkinen T; Simard J; Spurdle AB; Beesley J; Chen X; ; Neuhausen SL; Ding YC; Couch FJ; Wang X; Fredericksen Z; Peterlongo P; Peissel B; Bonanni B; Viel A; Bernard L; Radice P; Szabo CI; Foretova L; Zikan M; Claes K; Greene MH; Mai PL; Rennert G; Lejbkowicz F; Andrulis IL; Ozcelik H; Glendon G; ; Gerdes AM; Thomassen M; Sunde L; Caligo MA; Laitman Y; Kontorovich T; Cohen S; Kaufman B; Dagan E; Baruch RG; Friedman E; Harbst K; Barbany-Bustinza G; Rantala J; Ehrencrona H; Karlsson P; Domchek SM; Nathanson KL; Osorio A; Blanco I; Lasa A; Benítez J; Hamann U; Hogervorst FB; Rookus MA; Collee JM; Devilee P; Ligtenberg MJ; van der Luijt RB; Aalfs CM; Waisfisz Q; Wijnen J; van Roozendaal CE; ; Peock S; Cook M; Frost D; Oliver C; Platte R; Evans DG; Lalloo F; Eeles R; Izatt L; Davidson R; Chu C; Eccles D; Cole T; Hodgson S; ; Godwin AK; Stoppa-Lyonnet D; Buecher B; Léoné M; Bressac-de Paillerets B; Remenieras A; Caron O; Lenoir GM; Sevenet N; Longy M; Ferrer SF; Prieur F; ; Goldgar D; Miron A; John EM; Buys SS; Daly MB; Hopper JL; Terry MB; Yassin Y; ; Singer C; Gschwantler-Kaulich D; Staudigl C; Hansen Tv; Barkardottir RB; Kirchhoff T; Pal P; Kosarin K; Offit K; Piedmonte M; Rodriguez GC; Wakeley K; Boggess JF; Basil J; Schwartz PE; Blank SV; Toland AE; Montagna M; Casella C; Imyanitov EN; Allavena A; Schmutzler RK; Versmold B; Engel C; Meindl A; Ditsch N; Arnold N; Niederacher D; Deissler H; Fiebig B; Suttner C; Schönbuchner I; Gadzicki D; Caldes T; de la Hoya M; Pooley KA; Easton DF; Chenevix-Trench G;
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  • 19. Evaluation of chromosome 6p22 as a breast cancer risk modifier locus in a follow-up study of BRCA2 mutation carriers.
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  • 20. Genetic modifiers of cancer risk for BRCA1 and BRCA2 mutation carriers.
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