BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

315 related articles for article (PubMed ID: 27799534)

  • 1. SARS-CoV 3CL protease cleaves its C-terminal autoprocessing site by novel subsite cooperativity.
    Muramatsu T; Takemoto C; Kim YT; Wang H; Nishii W; Terada T; Shirouzu M; Yokoyama S
    Proc Natl Acad Sci U S A; 2016 Nov; 113(46):12997-13002. PubMed ID: 27799534
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Optimization of quenched fluorescent peptide substrates of SARS-CoV-2 3CL
    Cesar Ramos de Jesus H; Solis N; Machado Y; Pablos I; Bell PA; Kappelhoff R; Grin PM; Sorgi CA; Butler GS; Overall CM
    J Virol; 2024 Jun; 98(6):e0004924. PubMed ID: 38742901
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Autoprocessing mechanism of severe acute respiratory syndrome coronavirus 3C-like protease (SARS-CoV 3CLpro) from its polyproteins.
    Muramatsu T; Kim YT; Nishii W; Terada T; Shirouzu M; Yokoyama S
    FEBS J; 2013 May; 280(9):2002-13. PubMed ID: 23452147
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Rapid peptide-based screening on the substrate specificity of severe acute respiratory syndrome (SARS) coronavirus 3C-like protease by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
    Chu LH; Choy WY; Tsai SN; Rao Z; Ngai SM
    Protein Sci; 2006 Apr; 15(4):699-709. PubMed ID: 16600962
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanism of the maturation process of SARS-CoV 3CL protease.
    Hsu MF; Kuo CJ; Chang KT; Chang HC; Chou CC; Ko TP; Shr HL; Chang GG; Wang AH; Liang PH
    J Biol Chem; 2005 Sep; 280(35):31257-66. PubMed ID: 15788388
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Kinetic and modeling studies of S3-S3' subsites of HIV proteinases.
    Tözsér J; Weber IT; Gustchina A; Bláha I; Copeland TD; Louis JM; Oroszlan S
    Biochemistry; 1992 May; 31(20):4793-800. PubMed ID: 1591240
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Maturation mechanism of severe acute respiratory syndrome (SARS) coronavirus 3C-like proteinase.
    Li C; Qi Y; Teng X; Yang Z; Wei P; Zhang C; Tan L; Zhou L; Liu Y; Lai L
    J Biol Chem; 2010 Sep; 285(36):28134-40. PubMed ID: 20489209
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Profiling of substrate specificity of SARS-CoV 3CL.
    Chuck CP; Chong LT; Chen C; Chow HF; Wan DC; Wong KB
    PLoS One; 2010 Oct; 5(10):e13197. PubMed ID: 20949131
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Insights into cleavage specificity from the crystal structure of foot-and-mouth disease virus 3C protease complexed with a peptide substrate.
    Zunszain PA; Knox SR; Sweeney TR; Yang J; Roqué-Rosell N; Belsham GJ; Leatherbarrow RJ; Curry S
    J Mol Biol; 2010 Jan; 395(2):375-89. PubMed ID: 19883658
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of Self-Processing Activities and Substrate Specificities of Porcine Torovirus 3C-Like Protease.
    Xu S; Zhou J; Chen Y; Tong X; Wang Z; Guo J; Chen J; Fang L; Wang D; Xiao S
    J Virol; 2020 Sep; 94(20):. PubMed ID: 32727876
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Peptide aldehyde inhibitors challenge the substrate specificity of the SARS-coronavirus main protease.
    Zhu L; George S; Schmidt MF; Al-Gharabli SI; Rademann J; Hilgenfeld R
    Antiviral Res; 2011 Nov; 92(2):204-12. PubMed ID: 21854807
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In silico analysis of ORF1ab in coronavirus HKU1 genome reveals a unique putative cleavage site of coronavirus HKU1 3C-like protease.
    Woo PC; Huang Y; Lau SK; Tsoi HW; Yuen KY
    Microbiol Immunol; 2005; 49(10):899-908. PubMed ID: 16237267
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ligand-induced Dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 Protease (3CLpro): IMPLICATIONS FOR nsp5 REGULATION AND THE DEVELOPMENT OF ANTIVIRALS.
    Tomar S; Johnston ML; St John SE; Osswald HL; Nyalapatla PR; Paul LN; Ghosh AK; Denison MR; Mesecar AD
    J Biol Chem; 2015 Aug; 290(32):19403-22. PubMed ID: 26055715
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Liberation of SARS-CoV main protease from the viral polyprotein: N-terminal autocleavage does not depend on the mature dimerization mode.
    Chen S; Jonas F; Shen C; Hilgenfeld R
    Protein Cell; 2010 Jan; 1(1):59-74. PubMed ID: 21203998
    [TBL] [Abstract][Full Text] [Related]  

  • 15. X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation.
    Lee J; Kenward C; Worrall LJ; Vuckovic M; Gentile F; Ton AT; Ng M; Cherkasov A; Strynadka NCJ; Paetzel M
    Nat Commun; 2022 Sep; 13(1):5196. PubMed ID: 36057636
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutational and inhibitive analysis of SARS coronavirus 3C-like protease by fluorescence resonance energy transfer-based assays.
    Kuang WF; Chow LP; Wu MH; Hwang LH
    Biochem Biophys Res Commun; 2005 Jun; 331(4):1554-9. PubMed ID: 15883050
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Analysis of the S3 and S3' subsite specificities of feline immunodeficiency virus (FIV) protease: development of a broad-based protease inhibitor efficacious against FIV, SIV, and HIV in vitro and ex vivo.
    Lee T; Laco GS; Torbett BE; Fox HS; Lerner DL; Elder JH; Wong CH
    Proc Natl Acad Sci U S A; 1998 Feb; 95(3):939-44. PubMed ID: 9448264
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutation of Gly-11 on the dimer interface results in the complete crystallographic dimer dissociation of severe acute respiratory syndrome coronavirus 3C-like protease: crystal structure with molecular dynamics simulations.
    Chen S; Hu T; Zhang J; Chen J; Chen K; Ding J; Jiang H; Shen X
    J Biol Chem; 2008 Jan; 283(1):554-564. PubMed ID: 17977841
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Profiling of substrate specificities of 3C-like proteases from group 1, 2a, 2b, and 3 coronaviruses.
    Chuck CP; Chow HF; Wan DC; Wong KB
    PLoS One; 2011; 6(11):e27228. PubMed ID: 22073294
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystallographic structure of wild-type SARS-CoV-2 main protease acyl-enzyme intermediate with physiological C-terminal autoprocessing site.
    Lee J; Worrall LJ; Vuckovic M; Rosell FI; Gentile F; Ton AT; Caveney NA; Ban F; Cherkasov A; Paetzel M; Strynadka NCJ
    Nat Commun; 2020 Nov; 11(1):5877. PubMed ID: 33208735
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.