These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 27803029)

  • 1. Prkar1a gene knockout in the pancreas leads to neuroendocrine tumorigenesis.
    Saloustros E; Salpea P; Starost M; Liu S; Faucz FR; London E; Szarek E; Song WJ; Hussain M; Stratakis CA
    Endocr Relat Cancer; 2017 Jan; 24(1):31-40. PubMed ID: 27803029
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PRKAR1A and the evolution of pituitary tumors.
    Kirschner LS
    Mol Cell Endocrinol; 2010 Sep; 326(1-2):3-7. PubMed ID: 20451576
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutations of the gene encoding the protein kinase A type I-alpha regulatory subunit (PRKAR1A) in patients with the "complex of spotty skin pigmentation, myxomas, endocrine overactivity, and schwannomas" (Carney complex).
    Stratakis CA
    Ann N Y Acad Sci; 2002 Jun; 968():3-21. PubMed ID: 12119264
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pancreatic ductal and acinar cell neoplasms in Carney complex: a possible new association.
    Gaujoux S; Tissier F; Ragazzon B; Rebours V; Saloustros E; Perlemoine K; Vincent-Dejean C; Meurette G; Cassagnau E; Dousset B; Bertagna X; Horvath A; Terris B; Carney JA; Stratakis CA; Bertherat J
    J Clin Endocrinol Metab; 2011 Nov; 96(11):E1888-95. PubMed ID: 21900385
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inactivation of the Carney complex gene 1 (PRKAR1A) alters spatiotemporal regulation of cAMP and cAMP-dependent protein kinase: a study using genetically encoded FRET-based reporters.
    Cazabat L; Ragazzon B; Varin A; Potier-Cartereau M; Vandier C; Vezzosi D; Risk-Rabin M; Guellich A; Schittl J; Lechêne P; Richter W; Nikolaev VO; Zhang J; Bertherat J; Vandecasteele G
    Hum Mol Genet; 2014 Mar; 23(5):1163-74. PubMed ID: 24122441
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Use of mouse models to understand the molecular basis of tissue-specific tumorigenesis in the Carney complex.
    Kirschner LS
    J Intern Med; 2009 Jul; 266(1):60-8. PubMed ID: 19522826
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inactivation of the Carney complex gene 1 (protein kinase A regulatory subunit 1A) inhibits SMAD3 expression and TGF beta-stimulated apoptosis in adrenocortical cells.
    Ragazzon B; Cazabat L; Rizk-Rabin M; Assie G; Groussin L; Fierrard H; Perlemoine K; Martinez A; Bertherat J
    Cancer Res; 2009 Sep; 69(18):7278-84. PubMed ID: 19738044
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A transgenic mouse bearing an antisense construct of regulatory subunit type 1A of protein kinase A develops endocrine and other tumours: comparison with Carney complex and other PRKAR1A induced lesions.
    Griffin KJ; Kirschner LS; Matyakhina L; Stergiopoulos SG; Robinson-White A; Lenherr SM; Weinberg FD; Claflin ES; Batista D; Bourdeau I; Voutetakis A; Sandrini F; Meoli EM; Bauer AJ; Cho-Chung YS; Bornstein SR; Carney JA; Stratakis CA
    J Med Genet; 2004 Dec; 41(12):923-31. PubMed ID: 15591278
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutation of Prkar1a causes osteoblast neoplasia driven by dysregulation of protein kinase A.
    Pavel E; Nadella K; Towns WH; Kirschner LS
    Mol Endocrinol; 2008 Feb; 22(2):430-40. PubMed ID: 17932105
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Haploinsufficiency for either one of the type-II regulatory subunits of protein kinase A improves the bone phenotype of Prkar1a+/- mice.
    Liu S; Saloustros E; Mertz EL; Tsang K; Starost MF; Salpea P; Faucz FR; Szarek E; Nesterova M; Leikin S; Stratakis CA
    Hum Mol Genet; 2015 Nov; 24(21):6080-92. PubMed ID: 26246497
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A Novel Missense PRKAR1A Variant Causes Carney Complex.
    Kim B; Jang HN; Chae KS; Shin HS; Kim YH; Kim SJ; Seong MW; Kim JH
    Endocrinol Metab (Seoul); 2022 Oct; 37(5):810-815. PubMed ID: 36193716
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protein kinase-A activity in PRKAR1A-mutant cells, and regulation of mitogen-activated protein kinases ERK1/2.
    Robinson-White A; Hundley TR; Shiferaw M; Bertherat J; Sandrini F; Stratakis CA
    Hum Mol Genet; 2003 Jul; 12(13):1475-84. PubMed ID: 12812976
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A mouse model for the Carney complex tumor syndrome develops neoplasia in cyclic AMP-responsive tissues.
    Kirschner LS; Kusewitt DF; Matyakhina L; Towns WH; Carney JA; Westphal H; Stratakis CA
    Cancer Res; 2005 Jun; 65(11):4506-14. PubMed ID: 15930266
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Functional Characterization of PRKAR1A Mutations Reveals a Unique Molecular Mechanism Causing Acrodysostosis but Multiple Mechanisms Causing Carney Complex.
    Rhayem Y; Le Stunff C; Abdel Khalek W; Auzan C; Bertherat J; Linglart A; Couvineau A; Silve C; Clauser E
    J Biol Chem; 2015 Nov; 290(46):27816-28. PubMed ID: 26405036
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Fibrolamellar carcinoma in the Carney complex: PRKAR1A loss instead of the classic DNAJB1-PRKACA fusion.
    Graham RP; Lackner C; Terracciano L; González-Cantú Y; Maleszewski JJ; Greipp PT; Simon SM; Torbenson MS
    Hepatology; 2018 Oct; 68(4):1441-1447. PubMed ID: 29222914
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PRKAR1A mutations in primary pigmented nodular adrenocortical disease.
    Cazabat L; Ragazzon B; Groussin L; Bertherat J
    Pituitary; 2006; 9(3):211-9. PubMed ID: 17036196
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Carney complex: an update.
    Correa R; Salpea P; Stratakis CA
    Eur J Endocrinol; 2015 Oct; 173(4):M85-97. PubMed ID: 26130139
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mouse Prkar1a haploinsufficiency leads to an increase in tumors in the Trp53+/- or Rb1+/- backgrounds and chemically induced skin papillomas by dysregulation of the cell cycle and Wnt signaling.
    Almeida MQ; Muchow M; Boikos S; Bauer AJ; Griffin KJ; Tsang KM; Cheadle C; Watkins T; Wen F; Starost MF; Bossis I; Nesterova M; Stratakis CA
    Hum Mol Genet; 2010 Apr; 19(8):1387-98. PubMed ID: 20080939
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular analysis of the cyclic AMP-dependent protein kinase A (PKA) regulatory subunit 1A (PRKAR1A) gene in patients with Carney complex and primary pigmented nodular adrenocortical disease (PPNAD) reveals novel mutations and clues for pathophysiology: augmented PKA signaling is associated with adrenal tumorigenesis in PPNAD.
    Groussin L; Kirschner LS; Vincent-Dejean C; Perlemoine K; Jullian E; Delemer B; Zacharieva S; Pignatelli D; Carney JA; Luton JP; Bertagna X; Stratakis CA; Bertherat J
    Am J Hum Genet; 2002 Dec; 71(6):1433-42. PubMed ID: 12424709
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The regulatory 1α subunit of protein kinase A modulates renal cystogenesis.
    Ye H; Wang X; Constans MM; Sussman CR; Chebib FT; Irazabal MV; Young WF; Harris PC; Kirschner LS; Torres VE
    Am J Physiol Renal Physiol; 2017 Sep; 313(3):F677-F686. PubMed ID: 28615245
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.