These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

192 related articles for article (PubMed ID: 27803065)

  • 1. A First-in-Human Phase I Study of a Bivalent MET Antibody, Emibetuzumab (LY2875358), as Monotherapy and in Combination with Erlotinib in Advanced Cancer.
    Rosen LS; Goldman JW; Algazi AP; Turner PK; Moser B; Hu T; Wang XA; Tuttle J; Wacheck V; Wooldridge JE; Banck M
    Clin Cancer Res; 2017 Apr; 23(8):1910-1919. PubMed ID: 27803065
    [No Abstract]   [Full Text] [Related]  

  • 2. A phase I dose-escalation study of LY2875358, a bivalent MET antibody, given as monotherapy or in combination with erlotinib or gefitinib in Japanese patients with advanced malignancies.
    Yoh K; Doi T; Ohmatsu H; Kojima T; Takahashi H; Zenke Y; Wacheck V; Enatsu S; Nakamura T; Turner K; Uenaka K
    Invest New Drugs; 2016 Oct; 34(5):584-95. PubMed ID: 27422720
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phase I Dose-Escalation Study of Linsitinib (OSI-906) and Erlotinib in Patients with Advanced Solid Tumors.
    Macaulay VM; Middleton MR; Eckhardt SG; Rudin CM; Juergens RA; Gedrich R; Gogov S; McCarthy S; Poondru S; Stephens AW; Gadgeel SM
    Clin Cancer Res; 2016 Jun; 22(12):2897-907. PubMed ID: 26831715
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A Randomized-Controlled Phase 2 Study of the MET Antibody Emibetuzumab in Combination with Erlotinib as First-Line Treatment for EGFR Mutation-Positive NSCLC Patients.
    Scagliotti G; Moro-Sibilot D; Kollmeier J; Favaretto A; Cho EK; Grosch H; Kimmich M; Girard N; Tsai CM; Hsia TC; Brighenti M; Schumann C; Wang XA; Wijayawardana SR; Gruver AM; Wallin J; Mansouri K; Wacheck V; Chang GC
    J Thorac Oncol; 2020 Jan; 15(1):80-90. PubMed ID: 31622732
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Safety, efficacy, and pharmacokinetics of navitoclax (ABT-263) in combination with erlotinib in patients with advanced solid tumors.
    Tolcher AW; LoRusso P; Arzt J; Busman TA; Lian G; Rudersdorf NS; Vanderwal CA; Kirschbrown W; Holen KD; Rosen LS
    Cancer Chemother Pharmacol; 2015 Nov; 76(5):1025-32. PubMed ID: 26420235
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Randomized, Open-Label Phase II Study Evaluating Emibetuzumab Plus Erlotinib and Emibetuzumab Monotherapy in MET Immunohistochemistry Positive NSCLC Patients with Acquired Resistance to Erlotinib.
    Camidge DR; Moran T; Demedts I; Grosch H; Mileham K; Molina J; Juan-Vidal O; Bepler G; Goldman JW; Park K; Wallin J; Wijayawardana SR; Wang XA; Wacheck V; Smit E
    Clin Lung Cancer; 2022 Jun; 23(4):300-310. PubMed ID: 35400584
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A Phase Ib/II Study of Ramucirumab in Combination with Emibetuzumab in Patients with Advanced Cancer.
    Harding JJ; Zhu AX; Bauer TM; Choueiri TK; Drilon A; Voss MH; Fuchs CS; Abou-Alfa GK; Wijayawardana SR; Wang XA; Moser BA; Uruñuela A; Wacheck V; Bendell JC
    Clin Cancer Res; 2019 Sep; 25(17):5202-5211. PubMed ID: 31142504
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A phase I dose-escalation study of Selumetinib in combination with Erlotinib or Temsirolimus in patients with advanced solid tumors.
    Infante JR; Cohen RB; Kim KB; Burris HA; Curt G; Emeribe U; Clemett D; Tomkinson HK; LoRusso PM
    Invest New Drugs; 2017 Oct; 35(5):576-588. PubMed ID: 28424891
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Safety and Pharmacokinetics/Pharmacodynamics of the First-in-Class Dual Action HER3/EGFR Antibody MEHD7945A in Locally Advanced or Metastatic Epithelial Tumors.
    Juric D; Dienstmann R; Cervantes A; Hidalgo M; Messersmith W; Blumenschein GR; Tabernero J; Roda D; Calles A; Jimeno A; Wang X; Bohórquez SS; Leddy C; Littman C; Kapp AV; Shames DS; Penuel E; Amler LC; Pirzkall A; Baselga J
    Clin Cancer Res; 2015 Jun; 21(11):2462-70. PubMed ID: 26034219
    [TBL] [Abstract][Full Text] [Related]  

  • 10. First-in-Human Phase I, Dose-Escalation and -Expansion Study of Telisotuzumab Vedotin, an Antibody-Drug Conjugate Targeting c-Met, in Patients With Advanced Solid Tumors.
    Strickler JH; Weekes CD; Nemunaitis J; Ramanathan RK; Heist RS; Morgensztern D; Angevin E; Bauer TM; Yue H; Motwani M; Parikh A; Reilly EB; Afar D; Naumovski L; Kelly K
    J Clin Oncol; 2018 Nov; 36(33):3298-3306. PubMed ID: 30285518
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Accelerating drug development by efficiently using emerging PK/PD data from an adaptable entry-into-human trial: example of lumretuzumab.
    Meneses-Lorente G; McIntyre C; Hsu JC; Thomas M; Jacob W; Adessi C; Weisser M
    Cancer Chemother Pharmacol; 2017 Jun; 79(6):1239-1247. PubMed ID: 28497320
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Safety, pharmacokinetics, and pharmacodynamics of AMG 102, a fully human hepatocyte growth factor-neutralizing monoclonal antibody, in a first-in-human study of patients with advanced solid tumors.
    Gordon MS; Sweeney CS; Mendelson DS; Eckhardt SG; Anderson A; Beaupre DM; Branstetter D; Burgess TL; Coxon A; Deng H; Kaplan-Lefko P; Leitch IM; Oliner KS; Yan L; Zhu M; Gore L
    Clin Cancer Res; 2010 Jan; 16(2):699-710. PubMed ID: 20068101
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phase I study of the HER3-targeted antibody patritumab (U3-1287) combined with erlotinib in Japanese patients with non-small cell lung cancer.
    Nishio M; Horiike A; Murakami H; Yamamoto N; Kaneda H; Nakagawa K; Horinouchi H; Nagashima M; Sekiguchi M; Tamura T
    Lung Cancer; 2015 Jun; 88(3):275-81. PubMed ID: 25891541
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phase I pharmacokinetic and pharmacodynamic dose-escalation study of RG7160 (GA201), the first glycoengineered monoclonal antibody against the epidermal growth factor receptor, in patients with advanced solid tumors.
    Paz-Ares LG; Gomez-Roca C; Delord JP; Cervantes A; Markman B; Corral J; Soria JC; Bergé Y; Roda D; Russell-Yarde F; Hollingsworth S; Baselga J; Umana P; Manenti L; Tabernero J
    J Clin Oncol; 2011 Oct; 29(28):3783-90. PubMed ID: 21900113
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phase I, dose-escalating study of elisidepsin (Irvalec(®)), a plasma membrane-disrupting marine antitumor agent, in combination with erlotinib in patients with advanced malignant solid tumors.
    Goel S; Viteri S; Morán T; Coronado C; Dios JL; Miguel-Lillo B; Fernández-García EM; Rosell R
    Invest New Drugs; 2016 Feb; 34(1):75-83. PubMed ID: 26627080
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MET-targeting antibody (emibetuzumab) and kinase inhibitor (merestinib) as single agent or in combination in a cancer model bearing MET exon 14 skipping.
    Yan SB; Um SL; Peek VL; Stephens JR; Zeng W; Konicek BW; Liu L; Manro JR; Wacheck V; Walgren RA
    Invest New Drugs; 2018 Aug; 36(4):536-544. PubMed ID: 29188469
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phase Ib Study of Lumretuzumab Plus Cetuximab or Erlotinib in Solid Tumor Patients and Evaluation of HER3 and Heregulin as Potential Biomarkers of Clinical Activity.
    Meulendijks D; Jacob W; Voest EE; Mau-Sorensen M; Martinez-Garcia M; Taus A; Fleitas T; Cervantes A; Lolkema MP; Langenberg MHG; De Jonge MJ; Sleijfer S; Han JY; Calles A; Felip E; Kim SW; Schellens JHM; Wilson S; Thomas M; Ceppi M; Meneses-Lorente G; James I; Vega-Harring S; Dua R; Nguyen M; Steiner L; Adessi C; Michielin F; Bossenmaier B; Weisser M; Lassen UN
    Clin Cancer Res; 2017 Sep; 23(18):5406-5415. PubMed ID: 28600476
    [No Abstract]   [Full Text] [Related]  

  • 18. A non-randomized, open-label, single-arm, Phase 2 study of emibetuzumab in Asian patients with MET diagnostic positive, advanced gastric cancer.
    Sakai D; Chung HC; Oh DY; Park SH; Kadowaki S; Kim YH; Tsuji A; Komatsu Y; Kang YK; Uenaka K; Wijayawardana SR; Wacheck V; Wang X; Yamamura A; Doi T
    Cancer Chemother Pharmacol; 2017 Dec; 80(6):1197-1207. PubMed ID: 29071414
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A phase Ib, dose-finding study of erlotinib in combination with a fixed dose of pertuzumab in patients with advanced non-small-cell lung cancer.
    Felip E; Ranson M; Cedrés S; Dean E; Brewster M; Martínez P; McNally V; Ross G; Galdermans D
    Clin Lung Cancer; 2012 Nov; 13(6):432-41. PubMed ID: 22609229
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phase I dose-escalation study of onartuzumab as a single agent and in combination with bevacizumab in patients with advanced solid malignancies.
    Salgia R; Patel P; Bothos J; Yu W; Eppler S; Hegde P; Bai S; Kaur S; Nijem I; Catenacci DV; Peterson A; Ratain MJ; Polite B; Mehnert JM; Moss RA
    Clin Cancer Res; 2014 Mar; 20(6):1666-75. PubMed ID: 24493831
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.