501 related articles for article (PubMed ID: 27803158)
1. TP53-inducible Glycolysis and Apoptosis Regulator (TIGAR) Metabolically Reprograms Carcinoma and Stromal Cells in Breast Cancer.
Ko YH; Domingo-Vidal M; Roche M; Lin Z; Whitaker-Menezes D; Seifert E; Capparelli C; Tuluc M; Birbe RC; Tassone P; Curry JM; Navarro-Sabaté À; Manzano A; Bartrons R; Caro J; Martinez-Outschoorn U
J Biol Chem; 2016 Dec; 291(51):26291-26303. PubMed ID: 27803158
[TBL] [Abstract][Full Text] [Related]
2. TP53 Induced Glycolysis and Apoptosis Regulator and Monocarboxylate Transporter 4 drive metabolic reprogramming with c-MYC and NFkB activation in breast cancer.
Roche ME; Ko YH; Domingo-Vidal M; Lin Z; Whitaker-Menezes D; Birbe RC; Tuluc M; Győrffy B; Caro J; Philp NJ; Bartrons R; Martinez-Outschoorn U
Int J Cancer; 2023 Nov; 153(9):1671-1683. PubMed ID: 37497753
[TBL] [Abstract][Full Text] [Related]
3. p53-TP53-Induced Glycolysis Regulator Mediated Glycolytic Suppression Attenuates DNA Damage and Genomic Instability in Fanconi Anemia Hematopoietic Stem Cells.
Li X; Wu L; Zopp M; Kopelov S; Du W
Stem Cells; 2019 Jul; 37(7):937-947. PubMed ID: 30977208
[TBL] [Abstract][Full Text] [Related]
4. Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells.
Martinez-Outschoorn UE; Goldberg A; Lin Z; Ko YH; Flomenberg N; Wang C; Pavlides S; Pestell RG; Howell A; Sotgia F; Lisanti MP
Cancer Biol Ther; 2011 Nov; 12(10):924-38. PubMed ID: 22041887
[TBL] [Abstract][Full Text] [Related]
5. Mitochondrial localization of TIGAR under hypoxia stimulates HK2 and lowers ROS and cell death.
Cheung EC; Ludwig RL; Vousden KH
Proc Natl Acad Sci U S A; 2012 Dec; 109(50):20491-6. PubMed ID: 23185017
[TBL] [Abstract][Full Text] [Related]
6. Structural and biochemical studies of TIGAR (TP53-induced glycolysis and apoptosis regulator).
Li H; Jogl G
J Biol Chem; 2009 Jan; 284(3):1748-54. PubMed ID: 19015259
[TBL] [Abstract][Full Text] [Related]
7. TIGAR, a p53-inducible regulator of glycolysis and apoptosis.
Bensaad K; Tsuruta A; Selak MA; Vidal MN; Nakano K; Bartrons R; Gottlieb E; Vousden KH
Cell; 2006 Jul; 126(1):107-20. PubMed ID: 16839880
[TBL] [Abstract][Full Text] [Related]
8. Acetylation mediated by the p300/CBP-associated factor determines cellular energy metabolic pathways in cancer.
Rajendran R; Garva R; Ashour H; Leung T; Stratford I; Krstic-Demonacos M; Demonacos C
Int J Oncol; 2013 Jun; 42(6):1961-72. PubMed ID: 23591450
[TBL] [Abstract][Full Text] [Related]
9. TP53 induced glycolysis and apoptosis regulator (TIGAR) knockdown results in radiosensitization of glioma cells.
Peña-Rico MA; Calvo-Vidal MN; Villalonga-Planells R; Martínez-Soler F; Giménez-Bonafé P; Navarro-Sabaté À; Tortosa A; Bartrons R; Manzano A
Radiother Oncol; 2011 Oct; 101(1):132-9. PubMed ID: 21864926
[TBL] [Abstract][Full Text] [Related]
10. ATM-NFκB axis-driven TIGAR regulates sensitivity of glioma cells to radiomimetics in the presence of TNFα.
Sinha S; Ghildiyal R; Mehta VS; Sen E
Cell Death Dis; 2013 May; 4(5):e615. PubMed ID: 23640457
[TBL] [Abstract][Full Text] [Related]
11. Therapeutic Targeting of the Warburg Effect in Pancreatic Cancer Relies on an Absence of p53 Function.
Rajeshkumar NV; Dutta P; Yabuuchi S; de Wilde RF; Martinez GV; Le A; Kamphorst JJ; Rabinowitz JD; Jain SK; Hidalgo M; Dang CV; Gillies RJ; Maitra A
Cancer Res; 2015 Aug; 75(16):3355-64. PubMed ID: 26113084
[TBL] [Abstract][Full Text] [Related]
12. Tp53-induced glycolysis and apoptosis regulator (TIGAR) protects glioma cells from starvation-induced cell death by up-regulating respiration and improving cellular redox homeostasis.
Wanka C; Steinbach JP; Rieger J
J Biol Chem; 2012 Sep; 287(40):33436-46. PubMed ID: 22887998
[TBL] [Abstract][Full Text] [Related]
13. Metabolic coupling and the Reverse Warburg Effect in cancer: Implications for novel biomarker and anticancer agent development.
Wilde L; Roche M; Domingo-Vidal M; Tanson K; Philp N; Curry J; Martinez-Outschoorn U
Semin Oncol; 2017 Jun; 44(3):198-203. PubMed ID: 29248131
[TBL] [Abstract][Full Text] [Related]
14. Tumor microenvironment and metabolic synergy in breast cancers: critical importance of mitochondrial fuels and function.
Martinez-Outschoorn U; Sotgia F; Lisanti MP
Semin Oncol; 2014 Apr; 41(2):195-216. PubMed ID: 24787293
[TBL] [Abstract][Full Text] [Related]
15. Sirtuin 3 Alleviates Diabetic Cardiomyopathy by Regulating TIGAR and Cardiomyocyte Metabolism.
Li L; Zeng H; He X; Chen JX
J Am Heart Assoc; 2021 Feb; 10(5):e018913. PubMed ID: 33586458
[TBL] [Abstract][Full Text] [Related]
16. p53 and TIGAR regulate cardiac myocyte energy homeostasis under hypoxic stress.
Kimata M; Matoba S; Iwai-Kanai E; Nakamura H; Hoshino A; Nakaoka M; Katamura M; Okawa Y; Mita Y; Okigaki M; Ikeda K; Tatsumi T; Matsubara H
Am J Physiol Heart Circ Physiol; 2010 Dec; 299(6):H1908-16. PubMed ID: 20935145
[TBL] [Abstract][Full Text] [Related]
17. Two p53-related metabolic regulators, TIGAR and SCO2, contribute to oroxylin A-mediated glucose metabolism in human hepatoma HepG2 cells.
Dai Q; Yin Y; Liu W; Wei L; Zhou Y; Li Z; You Q; Lu N; Guo Q
Int J Biochem Cell Biol; 2013 Jul; 45(7):1468-78. PubMed ID: 23612020
[TBL] [Abstract][Full Text] [Related]
18. Akt mediates TIGAR induction in HeLa cells following PFKFB3 inhibition.
Simon-Molas H; Calvo-Vidal MN; Castaño E; Rodríguez-García A; Navarro-Sabaté À; Bartrons R; Manzano A
FEBS Lett; 2016 Sep; 590(17):2915-26. PubMed ID: 27491040
[TBL] [Abstract][Full Text] [Related]
19. Indoleamine 2,3-dioxygenase increases p53 levels in alloreactive human T cells, and both indoleamine 2,3-dioxygenase and p53 suppress glucose uptake, glycolysis and proliferation.
Eleftheriadis T; Pissas G; Antoniadi G; Spanoulis A; Liakopoulos V; Stefanidis I
Int Immunol; 2014 Dec; 26(12):673-84. PubMed ID: 25064493
[TBL] [Abstract][Full Text] [Related]
20. TIGAR cooperated with glycolysis to inhibit the apoptosis of leukemia cells and associated with poor prognosis in patients with cytogenetically normal acute myeloid leukemia.
Qian S; Li J; Hong M; Zhu Y; Zhao H; Xie Y; Huang J; Lian Y; Li Y; Wang S; Mao J; Chen Y
J Hematol Oncol; 2016 Nov; 9(1):128. PubMed ID: 27884166
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
