BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

120 related articles for article (PubMed ID: 27805296)

  • 1. The sensitivity of head and neck carcinoma cells to statins is related to the expression of their Ras expression status, and statin-induced apoptosis is mediated via suppression of the Ras/ERK and Ras/mTOR pathways.
    Tsubaki M; Fujiwara D; Takeda T; Kino T; Tomonari Y; Itoh T; Imano M; Satou T; Sakaguchi K; Nishida S
    Clin Exp Pharmacol Physiol; 2017 Feb; 44(2):222-234. PubMed ID: 27805296
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Statins induce apoptosis through inhibition of Ras signaling pathways and enhancement of Bim and p27 expression in human hematopoietic tumor cells.
    Fujiwara D; Tsubaki M; Takeda T; Tomonari Y; Koumoto YI; Sakaguchi K; Nishida S
    Tumour Biol; 2017 Oct; 39(10):1010428317734947. PubMed ID: 28990465
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nitrogen-containing bisphosphonates induce apoptosis of hematopoietic tumor cells via inhibition of Ras signaling pathways and Bim-mediated activation of the intrinsic apoptotic pathway.
    Tsubaki M; Itoh T; Satou T; Imano M; Komai M; Ogawa N; Mukai J; Nishida S
    Biochem Pharmacol; 2013 Jan; 85(2):163-72. PubMed ID: 23085435
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Statins inhibited the MIP-1α expression via inhibition of Ras/ERK and Ras/Akt pathways in myeloma cells.
    Tsubaki M; Mashimo K; Takeda T; Kino T; Fujita A; Itoh T; Imano M; Sakaguchi K; Satou T; Nishida S
    Biomed Pharmacother; 2016 Mar; 78():23-29. PubMed ID: 26898421
    [TBL] [Abstract][Full Text] [Related]  

  • 5. FTI-277 and GGTI-289 induce apoptosis via inhibition of the Ras/ERK and Ras/mTOR pathway in head and neck carcinoma HEp-2 and HSC-3 cells.
    Tateishi K; Tsubaki M; Takeda T; Yamatomo Y; Imano M; Satou T; Nishida S
    J BUON; 2021; 26(2):606-612. PubMed ID: 34077012
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Linalool induces cell cycle arrest and apoptosis in HepG2 cells through oxidative stress generation and modulation of Ras/MAPK and Akt/mTOR pathways.
    Rodenak-Kladniew B; Castro A; Stärkel P; De Saeger C; García de Bravo M; Crespo R
    Life Sci; 2018 Apr; 199():48-59. PubMed ID: 29510199
    [TBL] [Abstract][Full Text] [Related]  

  • 7. [Fluvastatin induces apoptosis on human tongue carcinoma cell line HSC-3].
    Fujiwara K; Tsubaki M; Yamazoe Y; Nishiura S; Kawaguchi T; Ogaki M; Nishinobo M; Shimamoto K; Moriyama K; Nishida S
    Yakugaku Zasshi; 2008 Jan; 128(1):153-8. PubMed ID: 18176067
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Statins inhibit proliferation and induce apoptosis in Barrett's esophageal adenocarcinoma cells.
    Ogunwobi OO; Beales IL
    Am J Gastroenterol; 2008 Apr; 103(4):825-37. PubMed ID: 18371146
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of statins and farnesyl transferase inhibitors on ERK phosphorylation, apoptosis and cell viability in non-small lung cancer cells.
    Pelaia G; Gallelli L; Renda T; Fratto D; Falcone D; Caraglia M; Busceti MT; Terracciano R; Vatrella A; Maselli R; Savino R
    Cell Prolif; 2012 Dec; 45(6):557-65. PubMed ID: 23045963
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Simvastatin antagonizes tumor necrosis factor-alpha inhibition of bone morphogenetic proteins-2-induced osteoblast differentiation by regulating Smad signaling and Ras/Rho-mitogen-activated protein kinase pathway.
    Yamashita M; Otsuka F; Mukai T; Otani H; Inagaki K; Miyoshi T; Goto J; Yamamura M; Makino H
    J Endocrinol; 2008 Mar; 196(3):601-13. PubMed ID: 18310456
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Statin-Induced Cancer Cell Death Can Be Mechanistically Uncoupled from Prenylation of RAS Family Proteins.
    Yu R; Longo J; van Leeuwen JE; Mullen PJ; Ba-Alawi W; Haibe-Kains B; Penn LZ
    Cancer Res; 2018 Mar; 78(5):1347-1357. PubMed ID: 29229608
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effect of simvastatin on cell proliferation and Ras activation in canine tumour cells.
    Kobayashi K; Baba K; Kambayashi S; Okuda M
    Vet Comp Oncol; 2021 Mar; 19(1):99-108. PubMed ID: 32779819
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthetic lethal interaction between PI3K/Akt/mTOR and Ras/MEK/ERK pathway inhibition in rhabdomyosarcoma.
    Guenther MK; Graab U; Fulda S
    Cancer Lett; 2013 Sep; 337(2):200-9. PubMed ID: 23684925
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma.
    Yanae M; Tsubaki M; Satou T; Itoh T; Imano M; Yamazoe Y; Nishida S
    J Exp Clin Cancer Res; 2011 Aug; 30(1):74. PubMed ID: 21831290
    [TBL] [Abstract][Full Text] [Related]  

  • 15. HMG-CoA reductase inhibitors upregulate heme oxygenase-1 expression in murine RAW264.7 macrophages via ERK, p38 MAPK and protein kinase G pathways.
    Chen JC; Huang KC; Lin WW
    Cell Signal; 2006 Jan; 18(1):32-9. PubMed ID: 16214041
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Simvastatin-induced breast cancer cell death and deactivation of PI3K/Akt and MAPK/ERK signalling are reversed by metabolic products of the mevalonate pathway.
    Wang T; Seah S; Loh X; Chan CW; Hartman M; Goh BC; Lee SC
    Oncotarget; 2016 Jan; 7(3):2532-44. PubMed ID: 26565813
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Anticancer activity of Ashwagandha against human head and neck cancer cell lines.
    Lee HE; Shin JA; Jeong JH; Jeon JG; Lee MH; Cho SD
    J Oral Pathol Med; 2016 Mar; 45(3):193-201. PubMed ID: 26332363
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Purified vitexin compound 1 induces apoptosis through activation of FOXO3a in hepatocellular carcinoma.
    Wang JG; Zheng XX; Zeng GY; Zhou YJ; Yuan H
    Oncol Rep; 2014 Jan; 31(1):488-96. PubMed ID: 24247909
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lovastatin inhibits oxidized low-density lipoprotein-induced plasminogen activator inhibitor and transforming growth factor-beta1 expression via a decrease in Ras/extracellular signal-regulated kinase activity in mesangial cells.
    Song CY; Kim BC; Lee HS
    Transl Res; 2008 Jan; 151(1):27-35. PubMed ID: 18061125
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lovastatin-induced up-regulation of the BH3-only protein, Bim, and cell death in glioblastoma cells.
    Jiang Z; Zheng X; Lytle RA; Higashikubo R; Rich KM
    J Neurochem; 2004 Apr; 89(1):168-78. PubMed ID: 15030401
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.