204 related articles for article (PubMed ID: 27809504)
21. Pharmacologic Characterization of JNJ-42226314, [1-(4-Fluorophenyl)indol-5-yl]-[3-[4-(thiazole-2-carbonyl)piperazin-1-yl]azetidin-1-yl]methanone, a Reversible, Selective, and Potent Monoacylglycerol Lipase Inhibitor.
Wyatt RM; Fraser I; Welty N; Lord B; Wennerholm M; Sutton S; Ameriks MK; Dugovic C; Yun S; White A; Nguyen L; Koudriakova T; Tian G; Suarez J; Szewczuk L; Bonnette W; Ahn K; Ghosh B; Flores CM; Connolly PJ; Zhu B; Macielag MJ; Brandt MR; Chevalier K; Zhang SP; Lovenberg T; Bonaventure P
J Pharmacol Exp Ther; 2020 Mar; 372(3):339-353. PubMed ID: 31818916
[TBL] [Abstract][Full Text] [Related]
22. A patent review of Monoacylglycerol Lipase (MAGL) inhibitors (2013-2017).
Granchi C; Caligiuri I; Minutolo F; Rizzolio F; Tuccinardi T
Expert Opin Ther Pat; 2017 Dec; 27(12):1341-1351. PubMed ID: 29053063
[TBL] [Abstract][Full Text] [Related]
23. In Vivo Characterization of the Ultrapotent Monoacylglycerol Lipase Inhibitor {4-[bis-(benzo[d][1,3]dioxol-5-yl)methyl]-piperidin-1-yl}(1H-1,2,4-triazol-1-yl)methanone (JJKK-048).
Aaltonen N; Kedzierska E; Orzelska-Górka J; Lehtonen M; Navia-Paldanius D; Jakupovic H; Savinainen JR; Nevalainen T; Laitinen JT; Parkkari T; Gynther M
J Pharmacol Exp Ther; 2016 Oct; 359(1):62-72. PubMed ID: 27451409
[TBL] [Abstract][Full Text] [Related]
24. (4-Phenoxyphenyl)tetrazolecarboxamides and related compounds as dual inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL).
Holtfrerich A; Hanekamp W; Lehr M
Eur J Med Chem; 2013 May; 63():64-75. PubMed ID: 23455058
[TBL] [Abstract][Full Text] [Related]
25. Discovery of Monoacylglycerol Lipase (MAGL) Inhibitors Based on a Pharmacophore-Guided Virtual Screening Study.
Jha V; Biagi M; Spinelli V; Di Stefano M; Macchia M; Minutolo F; Granchi C; Poli G; Tuccinardi T
Molecules; 2020 Dec; 26(1):. PubMed ID: 33375358
[TBL] [Abstract][Full Text] [Related]
26. Docking based virtual screening and molecular dynamics study to identify potential monoacylglycerol lipase inhibitors.
Afzal O; Kumar S; Kumar R; Firoz A; Jaggi M; Bawa S
Bioorg Med Chem Lett; 2014 Aug; 24(16):3986-96. PubMed ID: 25011912
[TBL] [Abstract][Full Text] [Related]
27. Loratadine analogues as MAGL inhibitors.
Patel JZ; Ahenkorah S; Vaara M; Staszewski M; Adams Y; Laitinen T; Navia-Paldanius D; Parkkari T; Savinainen JR; Walczyński K; Laitinen JT; Nevalainen TJ
Bioorg Med Chem Lett; 2015 Apr; 25(7):1436-42. PubMed ID: 25752982
[TBL] [Abstract][Full Text] [Related]
28. Discovery of novel reversible monoacylglycerol lipase inhibitors via docking-based virtual screening.
Xiong F; Ding X; Zhang H; Luo X; Chen K; Jiang H; Luo C; Xu H
Bioorg Med Chem Lett; 2021 Jun; 41():127986. PubMed ID: 33766770
[TBL] [Abstract][Full Text] [Related]
29. Synthesis and pharmacological evaluation of 2,4-dinitroaryldithiocarbamate derivatives as novel monoacylglycerol lipase inhibitors.
Kapanda CN; Masquelier J; Labar G; Muccioli GG; Poupaert JH; Lambert DM
J Med Chem; 2012 Jun; 55(12):5774-83. PubMed ID: 22651858
[TBL] [Abstract][Full Text] [Related]
30. Rational Development of MAGL Inhibitors.
Granchi C; Rizzolio F; Caligiuri I; Macchia M; Martinelli A; Minutolo F; Tuccinardi T
Methods Mol Biol; 2018; 1824():335-346. PubMed ID: 30039417
[TBL] [Abstract][Full Text] [Related]
31. Design, Synthesis, and Evaluation of Reversible and Irreversible Monoacylglycerol Lipase Positron Emission Tomography (PET) Tracers Using a "Tail Switching" Strategy on a Piperazinyl Azetidine Skeleton.
Chen Z; Mori W; Deng X; Cheng R; Ogasawara D; Zhang G; Schafroth MA; Dahl K; Fu H; Hatori A; Shao T; Zhang Y; Yamasaki T; Zhang X; Rong J; Yu Q; Hu K; Fujinaga M; Xie L; Kumata K; Gou Y; Chen J; Gu S; Bao L; Wang L; Collier TL; Vasdev N; Shao Y; Ma JA; Cravatt BF; Fowler C; Josephson L; Zhang MR; Liang SH
J Med Chem; 2019 Apr; 62(7):3336-3353. PubMed ID: 30829483
[TBL] [Abstract][Full Text] [Related]
32. Synthesis and preclinical evaluation of [
Ahamed M; Attili B; van Veghel D; Ooms M; Berben P; Celen S; Koole M; Declercq L; Savinainen JR; Laitinen JT; Verbruggen A; Bormans G
Eur J Med Chem; 2017 Aug; 136():104-113. PubMed ID: 28486208
[TBL] [Abstract][Full Text] [Related]
33. The design, synthesis and biological evaluation of novel URB602 analogues as potential monoacylglycerol lipase inhibitors.
Szabo M; Agostino M; Malone DT; Yuriev E; Capuano B
Bioorg Med Chem Lett; 2011 Nov; 21(22):6782-7. PubMed ID: 21982493
[TBL] [Abstract][Full Text] [Related]
34. Design, synthesis, ADME and biological evaluation of benzylpiperidine and benzylpiperazine derivatives as novel reversible monoacylglycerol lipase (MAGL) inhibitors.
Di Stefano M; Masoni S; Bononi G; Poli G; Galati S; Gado F; Manzi S; Vagaggini C; Brai A; Caligiuri I; Asif K; Rizzolio F; Macchia M; Chicca A; Sodi A; Di Bussolo V; Minutolo F; Meier P; Gertsch J; Granchi C; Dreassi E; Tuccinardi T
Eur J Med Chem; 2024 Jan; 263():115916. PubMed ID: 37976705
[TBL] [Abstract][Full Text] [Related]
35. Design, synthesis and biological activity of 4-(4-benzyloxy)phenoxypiperidines as selective and reversible LSD1 inhibitors.
Xi J; Xu S; Zhang L; Bi X; Ren Y; Liu YC; Gu Y; Xu Y; Lan F; Zha X
Bioorg Chem; 2018 Aug; 78():7-16. PubMed ID: 29524666
[TBL] [Abstract][Full Text] [Related]
36. A reversible and selective inhibitor of monoacylglycerol lipase ameliorates multiple sclerosis.
Hernández-Torres G; Cipriano M; Hedén E; Björklund E; Canales Á; Zian D; Feliú A; Mecha M; Guaza C; Fowler CJ; Ortega-Gutiérrez S; López-Rodríguez ML
Angew Chem Int Ed Engl; 2014 Dec; 53(50):13765-70. PubMed ID: 25298214
[TBL] [Abstract][Full Text] [Related]
37. Set-Up and Validation of a High Throughput Screening Method for Human Monoacylglycerol Lipase (MAGL) Based on a New Red Fluorescent Probe.
Miceli M; Casati S; Ottria R; Di Leo S; Eberini I; Palazzolo L; Parravicini C; Ciuffreda P
Molecules; 2019 Jun; 24(12):. PubMed ID: 31208066
[TBL] [Abstract][Full Text] [Related]
38. Synthesis and evaluation of carbamate derivatives as fatty acid amide hydrolase and monoacylglycerol lipase inhibitors.
Jaiswal S; Gupta G; Ayyannan SR
Arch Pharm (Weinheim); 2022 Nov; 355(11):e2200081. PubMed ID: 35924298
[TBL] [Abstract][Full Text] [Related]
39. ω-Quinazolinonylalkyl aryl ureas as reversible inhibitors of monoacylglycerol lipase.
Dato FM; Neudörfl JM; Gütschow M; Goldfuss B; Pietsch M
Bioorg Chem; 2020 Jan; 94():103352. PubMed ID: 31668797
[TBL] [Abstract][Full Text] [Related]
40. Comparative biochemical characterization of the monoacylglycerol lipase inhibitor KML29 in brain, spinal cord, liver, spleen, fat and muscle tissue.
Pasquarelli N; Porazik C; Hanselmann J; Weydt P; Ferger B; Witting A
Neuropharmacology; 2015 Apr; 91():148-56. PubMed ID: 25497453
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
