BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

311 related articles for article (PubMed ID: 27810591)

  • 21. Evaluation of WO2014207069 A1: Multitarget Hedgehog pathway inhibitors and uses thereof.
    Manetti F; Petricci E
    Expert Opin Ther Pat; 2016; 26(4):529-35. PubMed ID: 26666870
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Genomic testing, tumor microenvironment and targeted therapy of Hedgehog-related human cancers.
    Katoh M
    Clin Sci (Lond); 2019 Apr; 133(8):953-970. PubMed ID: 31036756
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Vismodegib, itraconazole and sonidegib as hedgehog pathway inhibitors and their relative competencies in the treatment of basal cell carcinomas.
    Wahid M; Jawed A; Mandal RK; Dar SA; Khan S; Akhter N; Haque S
    Crit Rev Oncol Hematol; 2016 Feb; 98():235-41. PubMed ID: 26614022
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype.
    Infante P; Alfonsi R; Ingallina C; Quaglio D; Ghirga F; D'Acquarica I; Bernardi F; Di Magno L; Canettieri G; Screpanti I; Gulino A; Botta B; Mori M; Di Marcotullio L
    Cell Death Dis; 2016 Sep; 7(9):e2376. PubMed ID: 27899820
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Potent inhibitors of the hedgehog signaling pathway.
    Brunton SA; Stibbard JH; Rubin LL; Kruse LI; Guicherit OM; Boyd EA; Price S
    J Med Chem; 2008 Mar; 51(5):1108-10. PubMed ID: 18275133
    [TBL] [Abstract][Full Text] [Related]  

  • 26. L-4, a Well-Tolerated and Orally Active Inhibitor of Hedgehog Pathway, Exhibited Potent Anti-tumor Effects Against Medulloblastoma
    Zhu M; Wang H; Wang C; Fang Y; Zhu T; Zhao W; Dong X; Zhang X
    Front Pharmacol; 2019; 10():89. PubMed ID: 30846937
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Novel 4-(2-pyrimidinylamino)benzamide derivatives as potent hedgehog signaling pathway inhibitors.
    Xin M; Zhang L; Tu C; Tang F; Wen J
    Bioorg Med Chem; 2018 Oct; 26(18):5029-5036. PubMed ID: 30249494
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Targeting the Oncoprotein Smoothened by Small Molecules: Focus on Novel Acylguanidine Derivatives as Potent Smoothened Inhibitors.
    Pietrobono S; Stecca B
    Cells; 2018 Dec; 7(12):. PubMed ID: 30558232
    [TBL] [Abstract][Full Text] [Related]  

  • 29. A novel hedgehog inhibitor for the treatment of hematological malignancies.
    Lin P; He Y; Chen G; Ma H; Zheng J; Zhang Z; Cao B; Zhang H; Zhang X; Mao X
    Anticancer Drugs; 2018 Nov; 29(10):995-1003. PubMed ID: 30106753
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Inhibition mechanism exploration of investigational drug TAK-441 as inhibitor against Vismodegib-resistant Smoothened mutant.
    Ishii T; Shimizu Y; Nakashima K; Kondo S; Ogawa K; Sasaki S; Matsui H
    Eur J Pharmacol; 2014 Jan; 723():305-13. PubMed ID: 24291104
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Berberine, a natural compound, suppresses Hedgehog signaling pathway activity and cancer growth.
    Wang J; Peng Y; Liu Y; Yang J; Ding N; Tan W
    BMC Cancer; 2015 Aug; 15():595. PubMed ID: 26296751
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The role of the Hedgehog signaling pathway in cancer: A comprehensive review.
    Skoda AM; Simovic D; Karin V; Kardum V; Vranic S; Serman L
    Bosn J Basic Med Sci; 2018 Feb; 18(1):8-20. PubMed ID: 29274272
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Scaffold hopping approach to a new series of smoothened antagonists.
    Lu W; Geng D; Sun Z; Yang Z; Ma H; Zheng J; Zhang X
    Bioorg Med Chem Lett; 2014 May; 24(10):2300-4. PubMed ID: 24726807
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Synthesis and evaluation of novel dimethylpyridazine derivatives as hedgehog signaling pathway inhibitors.
    Wang C; Zhu M; Lu X; Wang H; Zhao W; Zhang X; Dong X
    Bioorg Med Chem; 2018 Jul; 26(12):3308-3320. PubMed ID: 29739714
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold.
    Berardozzi S; Bernardi F; Infante P; Ingallina C; Toscano S; De Paolis E; Alfonsi R; Caimano M; Botta B; Mori M; Di Marcotullio L; Ghirga F
    Eur J Med Chem; 2018 Aug; 156():554-562. PubMed ID: 30025349
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Vismodegib.
    Meiss F; Zeiser R
    Recent Results Cancer Res; 2014; 201():405-17. PubMed ID: 24756807
    [TBL] [Abstract][Full Text] [Related]  

  • 37. ABT-199 inhibits Hedgehog pathway by acting as a competitive inhibitor of oxysterol, rather as a BH3 mimetic.
    Wang J; Zhang Y; Huang WJ; Yang J; Tang WG; Huang TM; Tan WF
    Acta Pharmacol Sin; 2021 Jun; 42(6):1005-1013. PubMed ID: 32855528
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Targeting Hedgehog signaling and understanding refractory response to treatment with Hedgehog pathway inhibitors.
    Queiroz KC; Spek CA; Peppelenbosch MP
    Drug Resist Updat; 2012 Aug; 15(4):211-22. PubMed ID: 22910179
    [TBL] [Abstract][Full Text] [Related]  

  • 39. AT-101 inhibits hedgehog pathway activity and cancer growth.
    Wang J; Peng Y; Liu Y; Yang J; Huang M; Tan W
    Cancer Chemother Pharmacol; 2015 Sep; 76(3):461-9. PubMed ID: 26113054
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Molecular pathways: novel approaches for improved therapeutic targeting of Hedgehog signaling in cancer stem cells.
    Justilien V; Fields AP
    Clin Cancer Res; 2015 Feb; 21(3):505-13. PubMed ID: 25646180
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 16.