189 related articles for article (PubMed ID: 27815979)
21. Structure of human FIH-1 reveals a unique active site pocket and interaction sites for HIF-1 and von Hippel-Lindau.
Lee C; Kim SJ; Jeong DG; Lee SM; Ryu SE
J Biol Chem; 2003 Feb; 278(9):7558-63. PubMed ID: 12482756
[TBL] [Abstract][Full Text] [Related]
22. Differences in hydroxylation and binding of Notch and HIF-1alpha demonstrate substrate selectivity for factor inhibiting HIF-1 (FIH-1).
Wilkins SE; Hyvärinen J; Chicher J; Gorman JJ; Peet DJ; Bilton RL; Koivunen P
Int J Biochem Cell Biol; 2009 Jul; 41(7):1563-71. PubMed ID: 19401150
[TBL] [Abstract][Full Text] [Related]
23. Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH).
Cockman ME; Lancaster DE; Stolze IP; Hewitson KS; McDonough MA; Coleman ML; Coles CH; Yu X; Hay RT; Ley SC; Pugh CW; Oldham NJ; Masson N; Schofield CJ; Ratcliffe PJ
Proc Natl Acad Sci U S A; 2006 Oct; 103(40):14767-72. PubMed ID: 17003112
[TBL] [Abstract][Full Text] [Related]
24. Kinetic Investigations of the Role of Factor Inhibiting Hypoxia-inducible Factor (FIH) as an Oxygen Sensor.
Tarhonskaya H; Hardy AP; Howe EA; Loik ND; Kramer HB; McCullagh JS; Schofield CJ; Flashman E
J Biol Chem; 2015 Aug; 290(32):19726-42. PubMed ID: 26112411
[TBL] [Abstract][Full Text] [Related]
25. Factor inhibiting HIF (FIH) recognizes distinct molecular features within hypoxia-inducible factor-α (HIF-α) versus ankyrin repeat substrates.
Wilkins SE; Karttunen S; Hampton-Smith RJ; Murchland I; Chapman-Smith A; Peet DJ
J Biol Chem; 2012 Mar; 287(12):8769-81. PubMed ID: 22270367
[TBL] [Abstract][Full Text] [Related]
26. MYPT1, the targeting subunit of smooth-muscle myosin phosphatase, is a substrate for the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH).
Webb JD; Murányi A; Pugh CW; Ratcliffe PJ; Coleman ML
Biochem J; 2009 May; 420(2):327-33. PubMed ID: 19245366
[TBL] [Abstract][Full Text] [Related]
27. Inhibition of the Oxygen-Sensing Asparaginyl Hydroxylase Factor Inhibiting Hypoxia-Inducible Factor: A Potential Hypoxia Response Modulating Strategy.
Wu Y; Li Z; McDonough MA; Schofield CJ; Zhang X
J Med Chem; 2021 Jun; 64(11):7189-7209. PubMed ID: 34029087
[TBL] [Abstract][Full Text] [Related]
28. Steady-state and transient kinetic analyses of taurine/alpha-ketoglutarate dioxygenase: effects of oxygen concentration, alternative sulfonates, and active-site variants on the FeIV-oxo intermediate.
Grzyska PK; Ryle MJ; Monterosso GR; Liu J; Ballou DP; Hausinger RP
Biochemistry; 2005 Mar; 44(10):3845-55. PubMed ID: 15751960
[TBL] [Abstract][Full Text] [Related]
29. Disruption of dimerization and substrate phosphorylation inhibit factor inhibiting hypoxia-inducible factor (FIH) activity.
Lancaster DE; McNeill LA; McDonough MA; Aplin RT; Hewitson KS; Pugh CW; Ratcliffe PJ; Schofield CJ
Biochem J; 2004 Nov; 383(Pt. 3):429-37. PubMed ID: 15239670
[TBL] [Abstract][Full Text] [Related]
30. Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway.
Dann CE; Bruick RK; Deisenhofer J
Proc Natl Acad Sci U S A; 2002 Nov; 99(24):15351-6. PubMed ID: 12432100
[TBL] [Abstract][Full Text] [Related]
31. Self-hydroxylation of taurine/alpha-ketoglutarate dioxygenase: evidence for more than one oxygen activation mechanism.
Koehntop KD; Marimanikkuppam S; Ryle MJ; Hausinger RP; Que L
J Biol Inorg Chem; 2006 Jan; 11(1):63-72. PubMed ID: 16320009
[TBL] [Abstract][Full Text] [Related]
32. FIH-dependent asparaginyl hydroxylation of ankyrin repeat domain-containing proteins.
Cockman ME; Webb JD; Ratcliffe PJ
Ann N Y Acad Sci; 2009 Oct; 1177():9-18. PubMed ID: 19845602
[TBL] [Abstract][Full Text] [Related]
33. Proteomics-based identification of novel factor inhibiting hypoxia-inducible factor (FIH) substrates indicates widespread asparaginyl hydroxylation of ankyrin repeat domain-containing proteins.
Cockman ME; Webb JD; Kramer HB; Kessler BM; Ratcliffe PJ
Mol Cell Proteomics; 2009 Mar; 8(3):535-46. PubMed ID: 18936059
[TBL] [Abstract][Full Text] [Related]
34. Oxygen-dependent hydroxylation by FIH regulates the TRPV3 ion channel.
Karttunen S; Duffield M; Scrimgeour NR; Squires L; Lim WL; Dallas ML; Scragg JL; Chicher J; Dave KA; Whitelaw ML; Peers C; Gorman JJ; Gleadle JM; Rychkov GY; Peet DJ
J Cell Sci; 2015 Jan; 128(2):225-31. PubMed ID: 25413349
[TBL] [Abstract][Full Text] [Related]
35. FIH permits NAA10 to catalyze the oxygen-dependent lysyl-acetylation of HIF-1α.
Kang J; Chun YS; Huh J; Park JW
Redox Biol; 2018 Oct; 19():364-374. PubMed ID: 30237125
[TBL] [Abstract][Full Text] [Related]
36. Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor.
Coleman ML; McDonough MA; Hewitson KS; Coles C; Mecinovic J; Edelmann M; Cook KM; Cockman ME; Lancaster DE; Kessler BM; Oldham NJ; Ratcliffe PJ; Schofield CJ
J Biol Chem; 2007 Aug; 282(33):24027-38. PubMed ID: 17573339
[TBL] [Abstract][Full Text] [Related]
37. Inhibitor of nuclear factor-kappaB alpha derepresses hypoxia-inducible factor-1 during moderate hypoxia by sequestering factor inhibiting hypoxia-inducible factor from hypoxia-inducible factor 1alpha.
Shin DH; Li SH; Yang SW; Lee BL; Lee MK; Park JW
FEBS J; 2009 Jul; 276(13):3470-80. PubMed ID: 19456861
[TBL] [Abstract][Full Text] [Related]
38. Factor inhibiting HIF-1 (FIH-1) modulates protein interactions of apoptosis-stimulating p53 binding protein 2 (ASPP2).
Janke K; Brockmeier U; Kuhlmann K; Eisenacher M; Nolde J; Meyer HE; Mairbäurl H; Metzen E
J Cell Sci; 2013 Jun; 126(Pt 12):2629-40. PubMed ID: 23606740
[TBL] [Abstract][Full Text] [Related]
39. Asparaginyl beta-hydroxylation of proteins containing ankyrin repeat domains influences their stability and function.
Hardy AP; Prokes I; Kelly L; Campbell ID; Schofield CJ
J Mol Biol; 2009 Oct; 392(4):994-1006. PubMed ID: 19646994
[TBL] [Abstract][Full Text] [Related]
40. Auto-hydroxylation of FIH-1: an Fe(ii), alpha-ketoglutarate-dependent human hypoxia sensor.
Chen YH; Comeaux LM; Eyles SJ; Knapp MJ
Chem Commun (Camb); 2008 Oct; (39):4768-70. PubMed ID: 18830487
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
