358 related articles for article (PubMed ID: 27819675)
1. Induction of endoplasmic reticulum stress by deletion of Grp78 depletes Apc mutant intestinal epithelial stem cells.
van Lidth de Jeude JF; Meijer BJ; Wielenga MCB; Spaan CN; Baan B; Rosekrans SL; Meisner S; Shen YH; Lee AS; Paton JC; Paton AW; Muncan V; van den Brink GR; Heijmans J
Oncogene; 2017 Jun; 36(24):3397-3405. PubMed ID: 27819675
[TBL] [Abstract][Full Text] [Related]
2. Wnt/β-catenin-mediated heat exposure inhibits intestinal epithelial cell proliferation and stem cell expansion through endoplasmic reticulum stress.
Zhou JY; Huang DG; Zhu M; Gao CQ; Yan HC; Li XG; Wang XQ
J Cell Physiol; 2020 Jul; 235(7-8):5613-5627. PubMed ID: 31960439
[TBL] [Abstract][Full Text] [Related]
3. Heterozygosity of Chaperone Grp78 Reduces Intestinal Stem Cell Regeneration Potential and Protects against Adenoma Formation.
van Lidth de Jeude JF; Spaan CN; Meijer BJ; Smit WL; Soeratram TTD; Wielenga MCB; Westendorp BF; Lee AS; Meisner S; Vermeulen JLM; Wildenberg ME; van den Brink GR; Muncan V; Heijmans J
Cancer Res; 2018 Nov; 78(21):6098-6106. PubMed ID: 30232220
[TBL] [Abstract][Full Text] [Related]
4. Olfactomedin 4 deletion induces colon adenocarcinoma in Apc
Liu W; Li H; Hong SH; Piszczek GP; Chen W; Rodgers GP
Oncogene; 2016 Oct; 35(40):5237-5247. PubMed ID: 26973250
[TBL] [Abstract][Full Text] [Related]
5. A knock-in mouse model reveals roles for nuclear Apc in cell proliferation, Wnt signal inhibition and tumor suppression.
Zeineldin M; Cunningham J; McGuinness W; Alltizer P; Cowley B; Blanchat B; Xu W; Pinson D; Neufeld KL
Oncogene; 2012 May; 31(19):2423-37. PubMed ID: 21996741
[TBL] [Abstract][Full Text] [Related]
6. Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation.
Martinez G; Wijesinghe M; Turner K; Abud HE; Taketo MM; Noda T; Robinson ML; de Iongh RU
Invest Ophthalmol Vis Sci; 2009 Oct; 50(10):4794-806. PubMed ID: 19515997
[TBL] [Abstract][Full Text] [Related]
7. Oncogenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapamycin complex 1 (mTORC1) in mice and zebrafish.
Valvezan AJ; Huang J; Lengner CJ; Pack M; Klein PS
Dis Model Mech; 2014 Jan; 7(1):63-71. PubMed ID: 24092877
[TBL] [Abstract][Full Text] [Related]
8. APC and oncogenic KRAS are synergistic in enhancing Wnt signaling in intestinal tumor formation and progression.
Janssen KP; Alberici P; Fsihi H; Gaspar C; Breukel C; Franken P; Rosty C; Abal M; El Marjou F; Smits R; Louvard D; Fodde R; Robine S
Gastroenterology; 2006 Oct; 131(4):1096-109. PubMed ID: 17030180
[TBL] [Abstract][Full Text] [Related]
9. A hypermorphic epithelial β-catenin mutation facilitates intestinal tumorigenesis in mice in response to compounding WNT-pathway mutations.
Buchert M; Rohde F; Eissmann M; Tebbutt N; Williams B; Tan CW; Owen A; Hirokawa Y; Gnann A; Orend G; Orner G; Dashwood RH; Heath JK; Ernst M; Janssen KP
Dis Model Mech; 2015 Nov; 8(11):1361-73. PubMed ID: 26398937
[TBL] [Abstract][Full Text] [Related]
10. Tissue-dependent consequences of Apc inactivation on proliferation and differentiation of ciliated cell progenitors via Wnt and notch signaling.
Li A; Chan B; Felix JC; Xing Y; Li M; Brody SL; Borok Z; Li C; Minoo P
PLoS One; 2013; 8(4):e62215. PubMed ID: 23646120
[TBL] [Abstract][Full Text] [Related]
11. Haploinsufficiency of Casitas B-Lineage Lymphoma Augments the Progression of Colon Cancer in the Background of Adenomatous Polyposis Coli Inactivation.
Richards S; Walker J; Nakanishi M; Belghasem M; Lyle C; Arinze N; Napoleon MA; Ravid JD; Crossland N; Zhao Q; Rosenberg D; Rahimi N; Chitalia VC
Am J Pathol; 2020 Mar; 190(3):602-613. PubMed ID: 32113662
[TBL] [Abstract][Full Text] [Related]
12. Up-regulation of CYP26A1 in adenomatous polyposis coli-deficient vertebrates via a WNT-dependent mechanism: implications for intestinal cell differentiation and colon tumor development.
Shelton DN; Sandoval IT; Eisinger A; Chidester S; Ratnayake A; Ireland CM; Jones DA
Cancer Res; 2006 Aug; 66(15):7571-7. PubMed ID: 16885356
[TBL] [Abstract][Full Text] [Related]
13. Proteomic profiling of a mouse model of acute intestinal Apc deletion leads to identification of potential novel biomarkers of human colorectal cancer (CRC).
Hammoudi A; Song F; Reed KR; Jenkins RE; Meniel VS; Watson AJ; Pritchard DM; Clarke AR; Jenkins JR
Biochem Biophys Res Commun; 2013 Oct; 440(3):364-70. PubMed ID: 23998936
[TBL] [Abstract][Full Text] [Related]
14. Vitamin D receptor deficiency enhances Wnt/β-catenin signaling and tumor burden in colon cancer.
Larriba MJ; Ordóñez-Morán P; Chicote I; Martín-Fernández G; Puig I; Muñoz A; Pálmer HG
PLoS One; 2011; 6(8):e23524. PubMed ID: 21858154
[TBL] [Abstract][Full Text] [Related]
15. Deletion of the WNT target and cancer stem cell marker CD44 in Apc(Min/+) mice attenuates intestinal tumorigenesis.
Zeilstra J; Joosten SP; Dokter M; Verwiel E; Spaargaren M; Pals ST
Cancer Res; 2008 May; 68(10):3655-61. PubMed ID: 18483247
[TBL] [Abstract][Full Text] [Related]
16. USP7 Is a Tumor-Specific WNT Activator for APC-Mutated Colorectal Cancer by Mediating β-Catenin Deubiquitination.
Novellasdemunt L; Foglizzo V; Cuadrado L; Antas P; Kucharska A; Encheva V; Snijders AP; Li VSW
Cell Rep; 2017 Oct; 21(3):612-627. PubMed ID: 29045831
[TBL] [Abstract][Full Text] [Related]
17. NOTUM from Apc-mutant cells biases clonal competition to initiate cancer.
Flanagan DJ; Pentinmikko N; Luopajärvi K; Willis NJ; Gilroy K; Raven AP; Mcgarry L; Englund JI; Webb AT; Scharaw S; Nasreddin N; Hodder MC; Ridgway RA; Minnee E; Sphyris N; Gilchrist E; Najumudeen AK; Romagnolo B; Perret C; Williams AC; Clevers H; Nummela P; Lähde M; Alitalo K; Hietakangas V; Hedley A; Clark W; Nixon C; Kirschner K; Jones EY; Ristimäki A; Leedham SJ; Fish PV; Vincent JP; Katajisto P; Sansom OJ
Nature; 2021 Jun; 594(7863):430-435. PubMed ID: 34079124
[TBL] [Abstract][Full Text] [Related]
18. Wnt-driven LARGE2 mediates laminin-adhesive O-glycosylation in human colonic epithelial cells and colorectal cancer.
Dietinger V; García de Durango CR; Wiechmann S; Boos SL; Michl M; Neumann J; Hermeking H; Kuster B; Jung P
Cell Commun Signal; 2020 Jun; 18(1):102. PubMed ID: 32586342
[TBL] [Abstract][Full Text] [Related]
19. Cytoskeleton out of the cupboard: colon cancer and cytoskeletal changes induced by loss of APC.
Näthke I
Nat Rev Cancer; 2006 Dec; 6(12):967-74. PubMed ID: 17093505
[TBL] [Abstract][Full Text] [Related]
20. miR-155 Is Downregulated in Familial Adenomatous Polyposis and Modulates WNT Signaling by Targeting AXIN1 and TCF4.
Prossomariti A; Piazzi G; D'Angelo L; Miccoli S; Turchetti D; Alquati C; Montagna C; Bazzoli F; Ricciardiello L
Mol Cancer Res; 2018 Dec; 16(12):1965-1976. PubMed ID: 30072583
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]