BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

455 related articles for article (PubMed ID: 27820874)

  • 1. Expression of Mutant Myocilin Induces Abnormal Intracellular Accumulation of Selected Extracellular Matrix Proteins in the Trabecular Meshwork.
    Kasetti RB; Phan TN; Millar JC; Zode GS
    Invest Ophthalmol Vis Sci; 2016 Nov; 57(14):6058-6069. PubMed ID: 27820874
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Topical ocular sodium 4-phenylbutyrate rescues glaucoma in a myocilin mouse model of primary open-angle glaucoma.
    Zode GS; Bugge KE; Mohan K; Grozdanic SD; Peters JC; Koehn DR; Anderson MG; Kardon RH; Stone EM; Sheffield VC
    Invest Ophthalmol Vis Sci; 2012 Mar; 53(3):1557-65. PubMed ID: 22328638
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma.
    Zode GS; Kuehn MH; Nishimura DY; Searby CC; Mohan K; Grozdanic SD; Bugge K; Anderson MG; Clark AF; Stone EM; Sheffield VC
    J Clin Invest; 2011 Sep; 121(9):3542-53. PubMed ID: 21821918
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Accumulation of Asn450Tyr mutant myocilin in ER promotes apoptosis of human trabecular meshwork cells.
    Yan X; Wu S; Liu Q; Li Y; Zhu W; Zhang J
    Mol Vis; 2020; 26():563-573. PubMed ID: 32818018
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Restoration of Aqueous Humor Outflow Following Transplantation of iPSC-Derived Trabecular Meshwork Cells in a Transgenic Mouse Model of Glaucoma.
    Zhu W; Jain A; Gramlich OW; Tucker BA; Sheffield VC; Kuehn MH
    Invest Ophthalmol Vis Sci; 2017 Apr; 58(4):2054-2062. PubMed ID: 28384726
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Histochemical Analysis of Glaucoma Caused by a Myocilin Mutation in a Human Donor Eye.
    van der Heide CJ; Alward WLM; Flamme-Wiese M; Riker M; Syed NA; Anderson MG; Carter K; Kuehn MH; Stone EM; Mullins RF; Fingert JH
    Ophthalmol Glaucoma; 2018; 1(2):132-138. PubMed ID: 30906929
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Autophagy stimulation reduces ocular hypertension in a murine glaucoma model via autophagic degradation of mutant myocilin.
    Kasetti RB; Maddineni P; Kiehlbauch C; Patil S; Searby CC; Levine B; Sheffield VC; Zode GS
    JCI Insight; 2021 Mar; 6(5):. PubMed ID: 33539326
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ex-vivo cultured human corneoscleral segment model to study the effects of glaucoma factors on trabecular meshwork.
    Kasetti RB; Patel PD; Maddineni P; Zode GS
    PLoS One; 2020; 15(6):e0232111. PubMed ID: 32579557
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Intracellular sequestration of hetero-oligomers formed by wild-type and glaucoma-causing myocilin mutants.
    Gobeil S; Rodrigue MA; Moisan S; Nguyen TD; Polansky JR; Morissette J; Raymond V
    Invest Ophthalmol Vis Sci; 2004 Oct; 45(10):3560-7. PubMed ID: 15452063
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutated myocilin and heterozygous Sod2 deficiency act synergistically in a mouse model of open-angle glaucoma.
    Joe MK; Nakaya N; Abu-Asab M; Tomarev SI
    Hum Mol Genet; 2015 Jun; 24(12):3322-34. PubMed ID: 25740847
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lentiviral mediated delivery of CRISPR/Cas9 reduces intraocular pressure in a mouse model of myocilin glaucoma.
    Patil SV; Kaipa BR; Ranshing S; Sundaresan Y; Millar JC; Nagarajan B; Kiehlbauch C; Zhang Q; Jain A; Searby CC; Scheetz TE; Clark AF; Sheffield VC; Zode GS
    Sci Rep; 2024 Mar; 14(1):6958. PubMed ID: 38521856
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Intraocular pressure across the lifespan of Tg-MYOC
    Zhang X; Xi G; Feng P; Li C; Kuehn MH; Zhu W
    Exp Eye Res; 2024 Apr; 241():109855. PubMed ID: 38453040
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tissue plasminogen activator attenuates outflow facility reduction in mouse model of juvenile open angle glaucoma.
    Gindina S; Hu Y; Barron AO; Qureshi Z; Danias J
    Exp Eye Res; 2020 Oct; 199():108179. PubMed ID: 32739292
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cross-talk between MYOC p. Y437H mutation and TGF-β2 in the pathology of glaucoma.
    Yang Y; Abdulatef ASWA; Zhang L; Jiang H; Zeng Z; Li H; Xia X
    Int J Med Sci; 2020; 17(8):1062-1070. PubMed ID: 32410836
    [No Abstract]   [Full Text] [Related]  

  • 15. Human Pro370Leu Mutant Myocilin Induces the Phenotype of Open-Angle Glaucoma in Transgenic Mice.
    Cheng Y; Wu S; Yan X; Liu Q; Lin D; Zhang J; Wang N
    Cell Mol Neurobiol; 2023 Jul; 43(5):2021-2033. PubMed ID: 36069958
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Gene expression profile in human trabecular meshwork from patients with primary open-angle glaucoma.
    Liu Y; Allingham RR; Qin X; Layfield D; Dellinger AE; Gibson J; Wheeler J; Ashley-Koch AE; Stamer WD; Hauser MA
    Invest Ophthalmol Vis Sci; 2013 Sep; 54(9):6382-9. PubMed ID: 24003086
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Glaucomatous MYOC mutations activate the IL-1/NF-κB inflammatory stress response and the glaucoma marker SELE in trabecular meshwork cells.
    Itakura T; Peters DM; Fini ME
    Mol Vis; 2015; 21():1071-84. PubMed ID: 26396484
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Astragaloside IV Attenuates Ocular Hypertension in a Mouse Model of TGFβ2 Induced Primary Open Angle Glaucoma.
    Kasetti RB; Maddineni P; Kodati B; Nagarajan B; Yacoub S
    Int J Mol Sci; 2021 Nov; 22(22):. PubMed ID: 34830390
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of Missense Extracellular Matrix Gene Variants in a Large Glaucoma Pedigree and Investigation of the N700S Thrombospondin-1 Variant in Normal and Glaucomatous Trabecular Meshwork Cells.
    Wirtz MK; Sykes R; Samples J; Edmunds B; Choi D; Keene DR; Tufa SF; Sun YY; Keller KE
    Curr Eye Res; 2022 Jan; 47(1):79-90. PubMed ID: 34143713
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Overexpression and properties of wild-type and Tyr437His mutated myocilin in the eyes of transgenic mice.
    Zillig M; Wurm A; Grehn FJ; Russell P; Tamm ER
    Invest Ophthalmol Vis Sci; 2005 Jan; 46(1):223-34. PubMed ID: 15623777
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.