499 related articles for article (PubMed ID: 27829214)
1. PICT-1 is a key nucleolar sensor in DNA damage response signaling that regulates apoptosis through the RPL11-MDM2-p53 pathway.
Chen H; Han L; Tsai H; Wang Z; Wu Y; Duo Y; Cao W; Chen L; Tan Z; Xu N; Huang X; Zhuang J; Huang L
Oncotarget; 2016 Dec; 7(50):83241-83257. PubMed ID: 27829214
[TBL] [Abstract][Full Text] [Related]
2. Acrolein preferentially damages nucleolus eliciting ribosomal stress and apoptosis in human cancer cells.
Wang HT; Chen TY; Weng CW; Yang CH; Tang MS
Oncotarget; 2016 Dec; 7(49):80450-80464. PubMed ID: 27741518
[TBL] [Abstract][Full Text] [Related]
3. PML regulates p53 stability by sequestering Mdm2 to the nucleolus.
Bernardi R; Scaglioni PP; Bergmann S; Horn HF; Vousden KH; Pandolfi PP
Nat Cell Biol; 2004 Jul; 6(7):665-72. PubMed ID: 15195100
[TBL] [Abstract][Full Text] [Related]
4. mTOR inhibitors blunt the p53 response to nucleolar stress by regulating RPL11 and MDM2 levels.
Goudarzi KM; Nistér M; Lindström MS
Cancer Biol Ther; 2014; 15(11):1499-514. PubMed ID: 25482947
[TBL] [Abstract][Full Text] [Related]
5. Regulation of the MDM2-p53 pathway by the nucleolar protein CSIG in response to nucleolar stress.
Xie N; Ma L; Zhu F; Zhao W; Tian F; Yuan F; Fu J; Huang D; Lv C; Tong T
Sci Rep; 2016 Nov; 6():36171. PubMed ID: 27811966
[TBL] [Abstract][Full Text] [Related]
6. Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11.
Sasaki M; Kawahara K; Nishio M; Mimori K; Kogo R; Hamada K; Itoh B; Wang J; Komatsu Y; Yang YR; Hikasa H; Horie Y; Yamashita T; Kamijo T; Zhang Y; Zhu Y; Prives C; Nakano T; Mak TW; Sasaki T; Maehama T; Mori M; Suzuki A
Nat Med; 2011 Jul; 17(8):944-51. PubMed ID: 21804542
[TBL] [Abstract][Full Text] [Related]
7. Heavy ion radiation-induced DNA damage mediates apoptosis via the Rpl27a-Rpl5-MDM2-p53/E2F1 signaling pathway in mouse spermatogonia.
Li H; Zhang H; Huang G; Dou Z; Xie Y; Si J; Di C
Ecotoxicol Environ Saf; 2020 Sep; 201():110831. PubMed ID: 32535367
[TBL] [Abstract][Full Text] [Related]
8. Constitutive Activation of DNA Damage Checkpoint Signaling Contributes to Mutant p53 Accumulation via Modulation of p53 Ubiquitination.
Frum RA; Love IM; Damle PK; Mukhopadhyay ND; Palit Deb S; Deb S; Grossman SR
Mol Cancer Res; 2016 May; 14(5):423-36. PubMed ID: 26965143
[TBL] [Abstract][Full Text] [Related]
9. ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage.
Chen L; Gilkes DM; Pan Y; Lane WS; Chen J
EMBO J; 2005 Oct; 24(19):3411-22. PubMed ID: 16163388
[TBL] [Abstract][Full Text] [Related]
10. ATM activates p53 by regulating MDM2 oligomerization and E3 processivity.
Cheng Q; Chen L; Li Z; Lane WS; Chen J
EMBO J; 2009 Dec; 28(24):3857-67. PubMed ID: 19816404
[TBL] [Abstract][Full Text] [Related]
11. hnRNP K: an HDM2 target and transcriptional coactivator of p53 in response to DNA damage.
Moumen A; Masterson P; O'Connor MJ; Jackson SP
Cell; 2005 Dec; 123(6):1065-78. PubMed ID: 16360036
[TBL] [Abstract][Full Text] [Related]
12. The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop.
Lu X; Ma O; Nguyen TA; Jones SN; Oren M; Donehower LA
Cancer Cell; 2007 Oct; 12(4):342-54. PubMed ID: 17936559
[TBL] [Abstract][Full Text] [Related]
13. PICT-1 triggers a pro-death autophagy through inhibiting rRNA transcription and AKT/mTOR/p70S6K signaling pathway.
Chen H; Duo Y; Hu B; Wang Z; Zhang F; Tsai H; Zhang J; Zhou L; Wang L; Wang X; Huang L
Oncotarget; 2016 Nov; 7(48):78747-78763. PubMed ID: 27729611
[TBL] [Abstract][Full Text] [Related]
14. HEY1 functions are regulated by its phosphorylation at Ser-68.
López-Mateo I; Arruabarrena-Aristorena A; Artaza-Irigaray C; López JA; Calvo E; Belandia B
Biosci Rep; 2016 Jul; 36(3):. PubMed ID: 27129302
[TBL] [Abstract][Full Text] [Related]
15. Inactivation of ribosomal protein S27-like confers radiosensitivity via the Mdm2-p53 and Mdm2-MRN-ATM axes.
Zhao Y; Tan M; Liu X; Xiong X; Sun Y
Cell Death Dis; 2018 Feb; 9(2):145. PubMed ID: 29396424
[TBL] [Abstract][Full Text] [Related]
16. Mutual protection of ribosomal proteins L5 and L11 from degradation is essential for p53 activation upon ribosomal biogenesis stress.
Bursać S; Brdovčak MC; Pfannkuchen M; Orsolić I; Golomb L; Zhu Y; Katz C; Daftuar L; Grabušić K; Vukelić I; Filić V; Oren M; Prives C; Volarevic S
Proc Natl Acad Sci U S A; 2012 Dec; 109(50):20467-72. PubMed ID: 23169665
[TBL] [Abstract][Full Text] [Related]
17. F-box protein FBXO31 directs degradation of MDM2 to facilitate p53-mediated growth arrest following genotoxic stress.
Malonia SK; Dutta P; Santra MK; Green MR
Proc Natl Acad Sci U S A; 2015 Jul; 112(28):8632-7. PubMed ID: 26124108
[TBL] [Abstract][Full Text] [Related]
18. LRRK2 interacts with ATM and regulates Mdm2-p53 cell proliferation axis in response to genotoxic stress.
Chen Z; Cao Z; Zhang W; Gu M; Zhou ZD; Li B; Li J; Tan EK; Zeng L
Hum Mol Genet; 2017 Nov; 26(22):4494-4505. PubMed ID: 28973420
[TBL] [Abstract][Full Text] [Related]
19. ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage.
Maya R; Balass M; Kim ST; Shkedy D; Leal JF; Shifman O; Moas M; Buschmann T; Ronai Z; Shiloh Y; Kastan MB; Katzir E; Oren M
Genes Dev; 2001 May; 15(9):1067-77. PubMed ID: 11331603
[TBL] [Abstract][Full Text] [Related]
20. Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage.
Pereg Y; Shkedy D; de Graaf P; Meulmeester E; Edelson-Averbukh M; Salek M; Biton S; Teunisse AF; Lehmann WD; Jochemsen AG; Shiloh Y
Proc Natl Acad Sci U S A; 2005 Apr; 102(14):5056-61. PubMed ID: 15788536
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
