504 related articles for article (PubMed ID: 27832841)
1. New Concepts in Dopamine D
Urs NM; Peterson SM; Caron MG
Biol Psychiatry; 2017 Jan; 81(1):78-85. PubMed ID: 27832841
[TBL] [Abstract][Full Text] [Related]
2. Distinct cortical and striatal actions of a β-arrestin-biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties.
Urs NM; Gee SM; Pack TF; McCorvy JD; Evron T; Snyder JC; Yang X; Rodriguiz RM; Borrelli E; Wetsel WC; Jin J; Roth BL; O'Donnell P; Caron MG
Proc Natl Acad Sci U S A; 2016 Dec; 113(50):E8178-E8186. PubMed ID: 27911814
[TBL] [Abstract][Full Text] [Related]
3. Elucidation of G-protein and β-arrestin functional selectivity at the dopamine D2 receptor.
Peterson SM; Pack TF; Wilkins AD; Urs NM; Urban DJ; Bass CE; Lichtarge O; Caron MG
Proc Natl Acad Sci U S A; 2015 Jun; 112(22):7097-102. PubMed ID: 25964346
[TBL] [Abstract][Full Text] [Related]
4. Effects of β-Arrestin-Biased Dopamine D2 Receptor Ligands on Schizophrenia-Like Behavior in Hypoglutamatergic Mice.
Park SM; Chen M; Schmerberg CM; Dulman RS; Rodriguiz RM; Caron MG; Jin J; Wetsel WC
Neuropsychopharmacology; 2016 Feb; 41(3):704-15. PubMed ID: 26129680
[TBL] [Abstract][Full Text] [Related]
5. A dopamine D2 receptor-DISC1 protein complex may contribute to antipsychotic-like effects.
Su P; Li S; Chen S; Lipina TV; Wang M; Lai TK; Lee FH; Zhang H; Zhai D; Ferguson SS; Nobrega JN; Wong AH; Roder JC; Fletcher PJ; Liu F
Neuron; 2014 Dec; 84(6):1302-16. PubMed ID: 25433637
[TBL] [Abstract][Full Text] [Related]
6. Antagonism of dopamine D2 receptor/beta-arrestin 2 interaction is a common property of clinically effective antipsychotics.
Masri B; Salahpour A; Didriksen M; Ghisi V; Beaulieu JM; Gainetdinov RR; Caron MG
Proc Natl Acad Sci U S A; 2008 Sep; 105(36):13656-61. PubMed ID: 18768802
[TBL] [Abstract][Full Text] [Related]
7. The role of beta-arrestin2 in shaping fMRI BOLD responses to dopaminergic stimulation.
Sahlholm K; Ielacqua GD; Xu J; Jones LA; Schlegel F; Mach RH; Rudin M; Schroeter A
Psychopharmacology (Berl); 2017 Jul; 234(13):2019-2030. PubMed ID: 28382543
[TBL] [Abstract][Full Text] [Related]
8. Functionally Biased D2R Antagonists: Targeting the β-Arrestin Pathway to Improve Antipsychotic Treatment.
Weïwer M; Xu Q; Gale JP; Lewis M; Campbell AJ; Schroeder FA; Van de Bittner GC; Walk M; Amaya A; Su P; D Ordevic L; Sacher JR; Skepner A; Fei D; Dennehy K; Nguyen S; Faloon PW; Perez J; Cottrell JR; Liu F; Palmer M; Pan JQ; Hooker JM; Zhang YL; Scolnick E; Wagner FF; Holson EB
ACS Chem Biol; 2018 Apr; 13(4):1038-1047. PubMed ID: 29485852
[TBL] [Abstract][Full Text] [Related]
9. Is regionally selective D2/D3 dopamine occupancy sufficient for atypical antipsychotic effect? an in vivo quantitative [123I]epidepride SPET study of amisulpride-treated patients.
Bressan RA; Erlandsson K; Jones HM; Mulligan R; Flanagan RJ; Ell PJ; Pilowsky LS
Am J Psychiatry; 2003 Aug; 160(8):1413-20. PubMed ID: 12900302
[TBL] [Abstract][Full Text] [Related]
10. Translational Modeling in Schizophrenia: Predicting Human Dopamine D2 Receptor Occupancy.
Johnson M; Kozielska M; Pilla Reddy V; Vermeulen A; Barton HA; Grimwood S; de Greef R; Groothuis GM; Danhof M; Proost JH
Pharm Res; 2016 Apr; 33(4):1003-17. PubMed ID: 26718955
[TBL] [Abstract][Full Text] [Related]
11. Dopamine D2 heteroreceptor complexes and their receptor-receptor interactions in ventral striatum: novel targets for antipsychotic drugs.
Fuxe K; Borroto-Escuela DO; Tarakanov AO; Romero-Fernandez W; Ferraro L; Tanganelli S; Perez-Alea M; Di Palma M; Agnati LF
Prog Brain Res; 2014; 211():113-39. PubMed ID: 24968778
[TBL] [Abstract][Full Text] [Related]
12. Antipsychotic-Like Efficacy of Dopamine D
Sahlholm K; Gómez-Soler M; Valle-León M; López-Cano M; Taura JJ; Ciruela F; Fernández-Dueñas V
Mol Neurobiol; 2018 Jun; 55(6):4952-4958. PubMed ID: 28779351
[TBL] [Abstract][Full Text] [Related]
13. Dopamine receptor heteromers: biasing antipsychotics.
Sahlholm K; Valle-León M; Fernández-Dueñas V; Ciruela F
Future Med Chem; 2018 Dec; 10(23):2675-2677. PubMed ID: 30518245
[No Abstract] [Full Text] [Related]
14. Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy.
Allen JA; Yost JM; Setola V; Chen X; Sassano MF; Chen M; Peterson S; Yadav PN; Huang XP; Feng B; Jensen NH; Che X; Bai X; Frye SV; Wetsel WC; Caron MG; Javitch JA; Roth BL; Jin J
Proc Natl Acad Sci U S A; 2011 Nov; 108(45):18488-93. PubMed ID: 22025698
[TBL] [Abstract][Full Text] [Related]
15. Engineered D2R Variants Reveal the Balanced and Biased Contributions of G-Protein and β-Arrestin to Dopamine-Dependent Functions.
Rose SJ; Pack TF; Peterson SM; Payne K; Borrelli E; Caron MG
Neuropsychopharmacology; 2018 Apr; 43(5):1164-1173. PubMed ID: 29068002
[TBL] [Abstract][Full Text] [Related]
16. Structure-Functional Selectivity Relationship Studies on A-86929 Analogs and Small Aryl Fragments toward the Discovery of Biased Dopamine D1 Receptor Agonists.
Li H; Mirabel R; Zimmerman J; Ghiviriga I; Phidd DK; Horenstein N; Urs NM
ACS Chem Neurosci; 2022 Jun; 13(12):1818-1831. PubMed ID: 35658399
[TBL] [Abstract][Full Text] [Related]
17. Schizophrenia model of elevated D2(High) receptors: haloperidol reverses the amphetamine-induced elevation in dopamine D2(High).
Seeman P
Schizophr Res; 2009 Apr; 109(1-3):191-2. PubMed ID: 19171464
[No Abstract] [Full Text] [Related]
18. The relationship between subjective well-being and dopamine D2 receptors in patients treated with a dopamine partial agonist and full antagonist antipsychotics.
Mizrahi R; Mamo D; Rusjan P; Graff A; Houle S; Kapur S
Int J Neuropsychopharmacol; 2009 Jun; 12(5):715-21. PubMed ID: 19366489
[TBL] [Abstract][Full Text] [Related]
19. Discovery of G Protein-Biased Dopaminergics with a Pyrazolo[1,5-a]pyridine Substructure.
Möller D; Banerjee A; Uzuneser TC; Skultety M; Huth T; Plouffe B; Hübner H; Alzheimer C; Friedland K; Müller CP; Bouvier M; Gmeiner P
J Med Chem; 2017 Apr; 60(7):2908-2929. PubMed ID: 28248104
[TBL] [Abstract][Full Text] [Related]
20. Mechanism of new antipsychotic medications: occupancy is not just antagonism.
Grunder G; Carlsson A; Wong DF
Arch Gen Psychiatry; 2003 Oct; 60(10):974-7. PubMed ID: 14557141
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
