These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

430 related articles for article (PubMed ID: 27834214)

  • 1. Motor neuron disease, TDP-43 pathology, and memory deficits in mice expressing ALS-FTD-linked UBQLN2 mutations.
    Le NT; Chang L; Kovlyagina I; Georgiou P; Safren N; Braunstein KE; Kvarta MD; Van Dyke AM; LeGates TA; Philips T; Morrison BM; Thompson SM; Puche AC; Gould TD; Rothstein JD; Wong PC; Monteiro MJ
    Proc Natl Acad Sci U S A; 2016 Nov; 113(47):E7580-E7589. PubMed ID: 27834214
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Serpin neuropathology in the P497S UBQLN2 mouse model of ALS/FTD.
    Higgins NR; Greenslade JE; Wu JJ; Miranda E; Galliciotti G; Monteiro MJ
    Brain Pathol; 2021 Sep; 31(5):e12948. PubMed ID: 33780087
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice.
    Ceballos-Diaz C; Rosario AM; Park HJ; Chakrabarty P; Sacino A; Cruz PE; Siemienski Z; Lara N; Moran C; Ravelo N; Golde TE; McFarland NR
    Mol Neurodegener; 2015 Jul; 10():25. PubMed ID: 26152284
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Neuronal Expression of UBQLN2
    Picher-Martel V; Renaud L; Bareil C; Julien JP
    Mol Neurobiol; 2019 Jul; 56(7):4680-4696. PubMed ID: 30377984
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Key role of UBQLN2 in pathogenesis of amyotrophic lateral sclerosis and frontotemporal dementia.
    Renaud L; Picher-Martel V; Codron P; Julien JP
    Acta Neuropathol Commun; 2019 Jul; 7(1):103. PubMed ID: 31319884
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Distribution of ubiquilin 2 and TDP-43 aggregates throughout the CNS in UBQLN2 p.T487I-linked amyotrophic lateral sclerosis and frontotemporal dementia.
    Nementzik LR; Thumbadoo KM; Murray HC; Gordon D; Yang S; Blair IP; Turner C; Faull RLM; Curtis MA; McLean C; Nicholson GA; Swanson MEV; Scotter EL
    Brain Pathol; 2024 May; 34(3):e13230. PubMed ID: 38115557
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Evidence of a link between ubiquilin 2 and optineurin in amyotrophic lateral sclerosis.
    Osaka M; Ito D; Yagi T; Nihei Y; Suzuki N
    Hum Mol Genet; 2015 Mar; 24(6):1617-29. PubMed ID: 25398946
    [TBL] [Abstract][Full Text] [Related]  

  • 8. TDP-43 expression in mouse models of amyotrophic lateral sclerosis and spinal muscular atrophy.
    Turner BJ; Bäumer D; Parkinson NJ; Scaber J; Ansorge O; Talbot K
    BMC Neurosci; 2008 Oct; 9():104. PubMed ID: 18957104
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Overexpression of UBQLN1 reduces neuropathology in the P497S UBQLN2 mouse model of ALS/FTD.
    Wang S; Tatman M; Monteiro MJ
    Acta Neuropathol Commun; 2020 Oct; 8(1):164. PubMed ID: 33028421
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ALS/FTD mutations in UBQLN2 are linked to mitochondrial dysfunction through loss-of-function in mitochondrial protein import.
    Lin BC; Phung TH; Higgins NR; Greenslade JE; Prado MA; Finley D; Karbowski M; Polster BM; Monteiro MJ
    Hum Mol Genet; 2021 Jun; 30(13):1230-1246. PubMed ID: 33891006
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel UBQLN2 mutations linked to amyotrophic lateral sclerosis and atypical hereditary spastic paraplegia phenotype through defective HSP70-mediated proteolysis.
    Teyssou E; Chartier L; Amador MD; Lam R; Lautrette G; Nicol M; Machat S; Da Barroca S; Moigneu C; Mairey M; Larmonier T; Saker S; Dussert C; Forlani S; Fontaine B; Seilhean D; Bohl D; Boillée S; Meininger V; Couratier P; Salachas F; Stevanin G; Millecamps S
    Neurobiol Aging; 2017 Oct; 58():239.e11-239.e20. PubMed ID: 28716533
    [TBL] [Abstract][Full Text] [Related]  

  • 12. UBQLN2/ubiquilin 2 mutation and pathology in familial amyotrophic lateral sclerosis.
    Williams KL; Warraich ST; Yang S; Solski JA; Fernando R; Rouleau GA; Nicholson GA; Blair IP
    Neurobiol Aging; 2012 Oct; 33(10):2527.e3-10. PubMed ID: 22717235
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hippocampal aggregation signatures of pathogenic UBQLN2 in amyotrophic lateral sclerosis and frontotemporal dementia.
    Thumbadoo KM; Dieriks BV; Murray HC; Swanson MEV; Yoo JH; Mehrabi NF; Turner C; Dragunow M; Faull RLM; Curtis MA; Siddique T; Shaw CE; Newell KL; Henden L; Williams KL; Nicholson GA; Scotter EL
    Brain; 2024 Oct; 147(10):3547-3561. PubMed ID: 38703371
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutation-dependent aggregation and toxicity in a Drosophila model for UBQLN2-associated ALS.
    Kim SH; Stiles SG; Feichtmeier JM; Ramesh N; Zhan L; Scalf MA; Smith LM; Pandey UB; Tibbetts RS
    Hum Mol Genet; 2018 Jan; 27(2):322-337. PubMed ID: 29161404
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Lack of TDP-43 abnormalities in mutant SOD1 transgenic mice shows disparity with ALS.
    Robertson J; Sanelli T; Xiao S; Yang W; Horne P; Hammond R; Pioro EP; Strong MJ
    Neurosci Lett; 2007 Jun; 420(2):128-32. PubMed ID: 17543992
    [TBL] [Abstract][Full Text] [Related]  

  • 16. UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
    Zhang K; Wang A; Zhong K; Qi S; Wei C; Shu X; Tu WY; Xu W; Xia C; Xiao Y; Chen A; Bai L; Zhang J; Luo B; Wang W; Shen C
    Neuron; 2021 Jun; 109(12):1949-1962.e6. PubMed ID: 33991504
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ALS/FTD mutations in UBQLN2 impede autophagy by reducing autophagosome acidification through loss of function.
    Wu JJ; Cai A; Greenslade JE; Higgins NR; Fan C; Le NTT; Tatman M; Whiteley AM; Prado MA; Dieriks BV; Curtis MA; Shaw CE; Siddique T; Faull RLM; Scotter EL; Finley D; Monteiro MJ
    Proc Natl Acad Sci U S A; 2020 Jun; 117(26):15230-15241. PubMed ID: 32513711
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways.
    Blokhuis AM; Koppers M; Groen EJN; van den Heuvel DMA; Dini Modigliani S; Anink JJ; Fumoto K; van Diggelen F; Snelting A; Sodaar P; Verheijen BM; Demmers JAA; Veldink JH; Aronica E; Bozzoni I; den Hertog J; van den Berg LH; Pasterkamp RJ
    Acta Neuropathol; 2016 Aug; 132(2):175-196. PubMed ID: 27164932
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Disturbance of proteasomal and autophagic protein degradation pathways by amyotrophic lateral sclerosis-linked mutations in ubiquilin 2.
    Osaka M; Ito D; Suzuki N
    Biochem Biophys Res Commun; 2016 Apr; 472(2):324-31. PubMed ID: 26944018
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A transgenic mouse expressing CHMP2Bintron5 mutant in neurons develops histological and behavioural features of amyotrophic lateral sclerosis and frontotemporal dementia.
    Vernay A; Therreau L; Blot B; Risson V; Dirrig-Grosch S; Waegaert R; Lequeu T; Sellal F; Schaeffer L; Sadoul R; Loeffler JP; René F
    Hum Mol Genet; 2016 Aug; 25(15):3341-3360. PubMed ID: 27329763
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.