BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

228 related articles for article (PubMed ID: 27835873)

  • 1. Proteomic identification of the oncoprotein STAT3 as a target of a novel Skp1 inhibitor.
    Cheng X; Liu YQ; Wang GZ; Yang LN; Lu YZ; Li XC; Zhou B; Qu LW; Wang XL; Cheng YX; Liu J; Tao SC; Zhou GB
    Oncotarget; 2017 Jan; 8(2):2681-2693. PubMed ID: 27835873
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Skp1 in lung cancer: clinical significance and therapeutic efficacy of its small molecule inhibitors.
    Liu YQ; Wang XL; Cheng X; Lu YZ; Wang GZ; Li XC; Zhang J; Wen ZS; Huang ZL; Gao QL; Yang LN; Cheng YX; Tao SC; Liu J; Zhou GB
    Oncotarget; 2015 Oct; 6(33):34953-67. PubMed ID: 26474281
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacogenomics and chemical library screens reveal a novel SCF
    Malek E; Abdel-Malek MA; Jagannathan S; Vad N; Karns R; Jegga AG; Broyl A; van Duin M; Sonneveld P; Cottini F; Anderson KC; Driscoll JJ
    Leukemia; 2017 Mar; 31(3):645-653. PubMed ID: 27677741
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Stratifin Inhibits SCF
    Shiba-Ishii A; Hong J; Hirokawa T; Kim Y; Nakagawa T; Sakashita S; Sakamoto N; Kozuma Y; Sato Y; Noguchi M
    Clin Cancer Res; 2019 May; 25(9):2809-2820. PubMed ID: 30728155
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Brusatol has therapeutic efficacy in non-small cell lung cancer by targeting Skp1 to inhibit cancer growth and metastasis.
    Xing S; Nong F; Wang Y; Huang D; Qin J; Chen YF; He DH; Wu PE; Huang H; Zhan R; Xu H; Liu YQ
    Pharmacol Res; 2022 Feb; 176():106059. PubMed ID: 34998973
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bortezomib (Velcade) induces p27Kip1 expression through S-phase kinase protein 2 degradation in colorectal cancer.
    Uddin S; Ahmed M; Bavi P; El-Sayed R; Al-Sanea N; AbdulJabbar A; Ashari LH; Alhomoud S; Al-Dayel F; Hussain AR; Al-Kuraya KS
    Cancer Res; 2008 May; 68(9):3379-88. PubMed ID: 18451165
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Small compound 6-O-angeloylplenolin induces mitotic arrest and exhibits therapeutic potentials in multiple myeloma.
    Liu Y; Chen XQ; Liang HX; Zhang FX; Zhang B; Jin J; Chen YL; Cheng YX; Zhou GB
    PLoS One; 2011; 6(7):e21930. PubMed ID: 21755010
    [TBL] [Abstract][Full Text] [Related]  

  • 8. FOXP3 is a novel transcriptional repressor for the breast cancer oncogene SKP2.
    Zuo T; Liu R; Zhang H; Chang X; Liu Y; Wang L; Zheng P; Liu Y
    J Clin Invest; 2007 Dec; 117(12):3765-73. PubMed ID: 18008005
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular dynamics simulations elucidate the mode of protein recognition by Skp1 and the F-box domain in the SCF complex.
    Chandra Dantu S; Nathubhai Kachariya N; Kumar A
    Proteins; 2016 Jan; 84(1):159-71. PubMed ID: 26573739
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phytochemical library screening reveals betulinic acid as a novel Skp2-SCF E3 ligase inhibitor in non-small cell lung cancer.
    He DH; Chen YF; Zhou YL; Zhang SB; Hong M; Yu X; Wei SF; Fan XZ; Li SY; Wang Q; Lu Y; Liu YQ
    Cancer Sci; 2021 Aug; 112(8):3218-3232. PubMed ID: 34080260
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Salinomycin induces cell death via inactivation of Stat3 and downregulation of Skp2.
    Koo KH; Kim H; Bae YK; Kim K; Park BK; Lee CH; Kim YN
    Cell Death Dis; 2013 Jun; 4(6):e693. PubMed ID: 23807222
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BIS targeting induces cellular senescence through the regulation of 14-3-3 zeta/STAT3/SKP2/p27 in glioblastoma cells.
    Lee JJ; Lee JS; Cui MN; Yun HH; Kim HY; Lee SH; Lee JH
    Cell Death Dis; 2014 Nov; 5(11):e1537. PubMed ID: 25412315
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21Cip1 and p27Kip1.
    Lin HP; Lin CY; Huo C; Hsiao PH; Su LC; Jiang SS; Chan TM; Chang CH; Chen LT; Kung HJ; Wang HD; Chuu CP
    Oncotarget; 2015 Mar; 6(9):6684-707. PubMed ID: 25788262
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A sesquiterpene lactone antrocin from Antrodia camphorata negatively modulates JAK2/STAT3 signaling via microRNA let-7c and induces apoptosis in lung cancer cells.
    Yeh CT; Huang WC; Rao YK; Ye M; Lee WH; Wang LS; Tzeng DT; Wu CH; Shieh YS; Huang CY; Chen YJ; Hsiao M; Wu AT; Yang Z; Tzeng YM
    Carcinogenesis; 2013 Dec; 34(12):2918-28. PubMed ID: 23880305
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Vorinostat enhances protein stability of p27 and p21 through negative regulation of Skp2 and Cks1 in human breast cancer cells.
    Uehara N; Yoshizawa K; Tsubura A
    Oncol Rep; 2012 Jul; 28(1):105-10. PubMed ID: 22484732
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of neddylation and deneddylation of cullin1 in SCFSkp2 ubiquitin ligase by F-box protein and substrate.
    Bornstein G; Ganoth D; Hershko A
    Proc Natl Acad Sci U S A; 2006 Aug; 103(31):11515-20. PubMed ID: 16861300
    [TBL] [Abstract][Full Text] [Related]  

  • 17. STAT3 interacts with Skp2/p27/p21 pathway to regulate the motility and invasion of gastric cancer cells.
    Wei Z; Jiang X; Qiao H; Zhai B; Zhang L; Zhang Q; Wu Y; Jiang H; Sun X
    Cell Signal; 2013 Apr; 25(4):931-8. PubMed ID: 23333463
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel synthetic bisindolylmaleimide alkaloids inhibit STAT3 activation by binding to the SH2 domain and suppress breast xenograft tumor growth.
    Li X; Ma H; Li L; Chen Y; Sun X; Dong Z; Liu JY; Zhu W; Zhang JT
    Oncogene; 2018 May; 37(18):2469-2480. PubMed ID: 29456240
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling.
    Zhu F; Dai C; Fu Y; Loo JF; Xia D; Gao SP; Ma Z; Chen Z
    Oncotarget; 2016 Feb; 7(8):9462-76. PubMed ID: 26843613
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Small-molecule inhibitors targeting the DNA-binding domain of STAT3 suppress tumor growth, metastasis and STAT3 target gene expression in vivo.
    Huang W; Dong Z; Chen Y; Wang F; Wang CJ; Peng H; He Y; Hangoc G; Pollok K; Sandusky G; Fu XY; Broxmeyer HE; Zhang ZY; Liu JY; Zhang JT
    Oncogene; 2016 Feb; 35(6):783-92. PubMed ID: 26073084
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.