BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

285 related articles for article (PubMed ID: 27836965)

  • 1. Exon- and contraction-dependent functions of titin in sarcomere assembly.
    Shih YH; Dvornikov AV; Zhu P; Ma X; Kim M; Ding Y; Xu X
    Development; 2016 Dec; 143(24):4713-4722. PubMed ID: 27836965
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Reading Frame Repair of
    Romano R; Ghahremani S; Zimmerman T; Legere N; Thakar K; Ladha FA; Pettinato AM; Hinson JT
    Circulation; 2022 Jan; 145(3):194-205. PubMed ID: 34905694
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Titin-truncating mutations associated with dilated cardiomyopathy alter length-dependent activation and its modulation via phosphorylation.
    Vikhorev PG; Vikhoreva NN; Yeung W; Li A; Lal S; Dos Remedios CG; Blair CA; Guglin M; Campbell KS; Yacoub MH; de Tombe P; Marston SB
    Cardiovasc Res; 2022 Jan; 118(1):241-253. PubMed ID: 33135063
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The assembly and evaluation of antisense oligonucleotides applied in exon skipping for titin-based mutations in dilated cardiomyopathy.
    Hahn JK; Neupane B; Pradhan K; Zhou Q; Testa L; Pelzl L; Maleck C; Gawaz M; Gramlich M
    J Mol Cell Cardiol; 2019 Jun; 131():12-19. PubMed ID: 30998980
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Truncated titin is structurally integrated into the human dilated cardiomyopathic sarcomere.
    Kellermayer D; Tordai H; Kiss B; Török G; Péter DM; Sayour AA; Pólos M; Hartyánszky I; Szilveszter B; Labeit S; Gángó A; Bedics G; Bödör C; Radovits T; Merkely B; Kellermayer MS
    J Clin Invest; 2024 Jan; 134(2):. PubMed ID: 37962957
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cronos Titin Is Expressed in Human Cardiomyocytes and Necessary for Normal Sarcomere Function.
    Zaunbrecher RJ; Abel AN; Beussman K; Leonard A; von Frieling-Salewsky M; Fields PA; Pabon L; Reinecke H; Yang X; Macadangdang J; Kim DH; Linke WA; Sniadecki NJ; Regnier M; Murry CE
    Circulation; 2019 Nov; 140(20):1647-1660. PubMed ID: 31587567
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A-Band Titin Truncation in Zebrafish Causes Dilated Cardiomyopathy and Hemodynamic Stress Intolerance.
    Huttner IG; Wang LW; Santiago CF; Horvat C; Johnson R; Cheng D; von Frieling-Salewsky M; Hillcoat K; Bemand TJ; Trivedi G; Braet F; Hesselson D; Alford K; Hayward CS; Seidman JG; Seidman CE; Feneley MP; Linke WA; Fatkin D
    Circ Genom Precis Med; 2018 Aug; 11(8):e002135. PubMed ID: 30354343
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Truncated titin proteins in dilated cardiomyopathy.
    McAfee Q; Chen CY; Yang Y; Caporizzo MA; Morley M; Babu A; Jeong S; Brandimarto J; Bedi KC; Flam E; Cesare J; Cappola TP; Margulies K; Prosser B; Arany Z
    Sci Transl Med; 2021 Nov; 13(618):eabd7287. PubMed ID: 34731015
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Allelic heterogeneity of TTNtv dilated cardiomyopathy can be modeled in adult zebrafish.
    Zhu P; Li J; Yan F; Islam S; Lin X; Xu X
    JCI Insight; 2024 Apr; 9(7):. PubMed ID: 38412038
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Titin mutations and muscle disease.
    Kellermayer D; Smith JE; Granzier H
    Pflugers Arch; 2019 May; 471(5):673-682. PubMed ID: 30919088
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Antisense-mediated exon skipping: a therapeutic strategy for titin-based dilated cardiomyopathy.
    Gramlich M; Pane LS; Zhou Q; Chen Z; Murgia M; Schötterl S; Goedel A; Metzger K; Brade T; Parrotta E; Schaller M; Gerull B; Thierfelder L; Aartsma-Rus A; Labeit S; Atherton JJ; McGaughran J; Harvey RP; Sinnecker D; Mann M; Laugwitz KL; Gawaz MP; Moretti A
    EMBO Mol Med; 2015 May; 7(5):562-76. PubMed ID: 25759365
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease.
    Roberts AM; Ware JS; Herman DS; Schafer S; Baksi J; Bick AG; Buchan RJ; Walsh R; John S; Wilkinson S; Mazzarotto F; Felkin LE; Gong S; MacArthur JA; Cunningham F; Flannick J; Gabriel SB; Altshuler DM; Macdonald PS; Heinig M; Keogh AM; Hayward CS; Banner NR; Pennell DJ; O'Regan DP; San TR; de Marvao A; Dawes TJ; Gulati A; Birks EJ; Yacoub MH; Radke M; Gotthardt M; Wilson JG; O'Donnell CJ; Prasad SK; Barton PJ; Fatkin D; Hubner N; Seidman JG; Seidman CE; Cook SA
    Sci Transl Med; 2015 Jan; 7(270):270ra6. PubMed ID: 25589632
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Relevance of truncating titin mutations in dilated cardiomyopathy.
    Akinrinade O; Alastalo TP; Koskenvuo JW
    Clin Genet; 2016 Jul; 90(1):49-54. PubMed ID: 26777568
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Abnormal contractility in human heart myofibrils from patients with dilated cardiomyopathy due to mutations in TTN and contractile protein genes.
    Vikhorev PG; Smoktunowicz N; Munster AB; Copeland O; Kostin S; Montgiraud C; Messer AE; Toliat MR; Li A; Dos Remedios CG; Lal S; Blair CA; Campbell KS; Guglin M; Richter M; Knöll R; Marston SB
    Sci Rep; 2017 Nov; 7(1):14829. PubMed ID: 29093449
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CRISPR Activation Reverses Haploinsufficiency and Functional Deficits Caused by
    Ghahremani S; Kanwal A; Pettinato A; Ladha F; Legere N; Thakar K; Zhu Y; Tjong H; Wilderman A; Stump WT; Greenberg L; Greenberg MJ; Cotney J; Wei CL; Hinson JT
    Circulation; 2024 Apr; 149(16):1285-1297. PubMed ID: 38235591
    [TBL] [Abstract][Full Text] [Related]  

  • 16. HEART DISEASE. Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy.
    Hinson JT; Chopra A; Nafissi N; Polacheck WJ; Benson CC; Swist S; Gorham J; Yang L; Schafer S; Sheng CC; Haghighi A; Homsy J; Hubner N; Church G; Cook SA; Linke WA; Chen CS; Seidman JG; Seidman CE
    Science; 2015 Aug; 349(6251):982-6. PubMed ID: 26315439
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Prevalence of Titin Truncating Variants in General Population.
    Akinrinade O; Koskenvuo JW; Alastalo TP
    PLoS One; 2015; 10(12):e0145284. PubMed ID: 26701604
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TTN truncation variants produce sarcomere-integrating proteins of uncertain functional significance.
    Hinson JT; Campbell SG
    J Clin Invest; 2024 Jan; 134(2):. PubMed ID: 38226618
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of Titin Missense Variants in Dilated Cardiomyopathy.
    Begay RL; Graw S; Sinagra G; Merlo M; Slavov D; Gowan K; Jones KL; Barbati G; Spezzacatene A; Brun F; Di Lenarda A; Smith JE; Granzier HL; Mestroni L; Taylor M;
    J Am Heart Assoc; 2015 Nov; 4(11):. PubMed ID: 26567375
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enrichment of titin-truncating variants in exon 327 in dilated cardiomyopathy and its relevance to reduced nonsense-mediated mRNA decay efficiency.
    Kim YG; Ha C; Shin S; Park JH; Jang JH; Kim JW
    Front Genet; 2022; 13():1087359. PubMed ID: 36685919
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.