These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

200 related articles for article (PubMed ID: 27838171)

  • 1. Design, synthesis and biological evaluation of 4,5-dibromo-N-(thiazol-2-yl)-1H-pyrrole-2-carboxamide derivatives as novel DNA gyrase inhibitors.
    Tomašič T; Mirt M; Barančoková M; Ilaš J; Zidar N; Tammela P; Kikelj D
    Bioorg Med Chem; 2017 Jan; 25(1):338-349. PubMed ID: 27838171
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis, and biological evaluation of 1-ethyl-3-(thiazol-2-yl)urea derivatives as Escherichia coli DNA gyrase inhibitors.
    Tomašič T; Barančoková M; Zidar N; Ilaš J; Tammela P; Kikelj D
    Arch Pharm (Weinheim); 2018 Jan; 351(1):. PubMed ID: 29239018
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of Benzothiazole Scaffold-Based DNA Gyrase B Inhibitors.
    Gjorgjieva M; Tomašič T; Barančokova M; Katsamakas S; Ilaš J; Tammela P; Peterlin Mašič L; Kikelj D
    J Med Chem; 2016 Oct; 59(19):8941-8954. PubMed ID: 27541007
    [TBL] [Abstract][Full Text] [Related]  

  • 4. New N-phenyl-4,5-dibromopyrrolamides and N-Phenylindolamides as ATPase inhibitors of DNA gyrase.
    Zidar N; Tomašič T; Macut H; Sirc A; Brvar M; Montalvão S; Tammela P; Ilaš J; Kikelj D
    Eur J Med Chem; 2016 Jul; 117():197-211. PubMed ID: 27100032
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular docking, discovery, synthesis, and pharmacological properties of new 6-substituted-2-(3-phenoxyphenyl)-4-phenyl quinoline derivatives; an approach to developing potent DNA gyrase inhibitors/antibacterial agents.
    Alagumuthu M; Arumugam S
    Bioorg Med Chem; 2017 Feb; 25(4):1448-1455. PubMed ID: 28094220
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, Synthesis, and Evaluation of Novel Tyrosine-Based DNA Gyrase B Inhibitors.
    Cotman AE; Trampuž M; Brvar M; Kikelj D; Ilaš J; Peterlin-Mašič L; Montalvão S; Tammela P; Frlan R
    Arch Pharm (Weinheim); 2017 Aug; 350(8):. PubMed ID: 28621824
    [TBL] [Abstract][Full Text] [Related]  

  • 7. New N-phenylpyrrolamide DNA gyrase B inhibitors: Optimization of efficacy and antibacterial activity.
    Durcik M; Lovison D; Skok Ž; Durante Cruz C; Tammela P; Tomašič T; Benedetto Tiz D; Draskovits G; Nyerges Á; Pál C; Ilaš J; Peterlin Mašič L; Kikelj D; Zidar N
    Eur J Med Chem; 2018 Jun; 154():117-132. PubMed ID: 29778894
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and Evaluation of N-Phenylpyrrolamides as DNA Gyrase B Inhibitors.
    Durcik M; Tammela P; Barančoková M; Tomašič T; Ilaš J; Kikelj D; Zidar N
    ChemMedChem; 2018 Jan; 13(2):186-198. PubMed ID: 29206345
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, and antibacterial activity of novel 4,5-dihydro-1H-pyrazole derivatives as DNA gyrase inhibitors.
    Liu JJ; Sun J; Fang YB; Yang YA; Jiao RH; Zhu HL
    Org Biomol Chem; 2014 Feb; 12(6):998-1008. PubMed ID: 24382549
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis and biological evaluation of α-substituted isonipecotic acid benzothiazole analogues as potent bacterial type II topoisomerase inhibitors.
    Axford LC; Agarwal PK; Anderson KH; Andrau LN; Atherall J; Barker S; Bennett JM; Blair M; Collins I; Czaplewski LG; Davies DT; Gannon CT; Kumar D; Lancett P; Logan A; Lunniss CJ; Mitchell DR; Offermann DA; Palmer JT; Palmer N; Pitt GR; Pommier S; Price D; Narasinga Rao B; Saxena R; Shukla T; Singh AK; Singh M; Srivastava A; Steele C; Stokes NR; Thomaides-Brears HB; Tyndall EM; Watson D; Haydon DJ
    Bioorg Med Chem Lett; 2013 Dec; 23(24):6598-603. PubMed ID: 24239017
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel 1,2,4-oxadiazole-chalcone/oxime hybrids as potential antibacterial DNA gyrase inhibitors: Design, synthesis, ADMET prediction and molecular docking study.
    Ibrahim TS; Almalki AJ; Moustafa AH; Allam RM; Abuo-Rahma GEA; El Subbagh HI; Mohamed MFA
    Bioorg Chem; 2021 Jun; 111():104885. PubMed ID: 33838559
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Exploring the interaction of N-(benzothiazol-2-yl)pyrrolamide DNA gyrase inhibitors with the GyrB ATP-binding site lipophilic floor: A medicinal chemistry and QTAIM study.
    Zidar N; Emanuel Cotman A; Sinnige W; Benek O; Barančokova M; Zega A; Peterlin Mašič L; Tomašič T; Ilaš J; Henderson SR; Mundy JEA; Maxwell A; Stevenson CEM; Lawson DM; Jan Sterk G; Tosso R; Gutierrez L; Enriz RD; Kikelj D
    Bioorg Med Chem; 2024 Jul; 109():117798. PubMed ID: 38906068
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Second-generation 4,5,6,7-tetrahydrobenzo[
    Lamut A; Skok Ž; Barančoková M; Gutierrez LJ; Cruz CD; Tammela P; Draskovits G; Szili PÉ; Nyerges Á; Pál C; Molek P; Bratkovič T; Ilaš J; Zidar N; Zega A; Enriz RD; Kikelj D; Tomašič T
    Future Med Chem; 2020 Feb; 12(4):277-297. PubMed ID: 32043377
    [No Abstract]   [Full Text] [Related]  

  • 14. N-thiadiazole-4-hydroxy-2-quinolone-3-carboxamides bearing heteroaromatic rings as novel antibacterial agents: Design, synthesis, biological evaluation and target identification.
    Xue W; Li X; Ma G; Zhang H; Chen Y; Kirchmair J; Xia J; Wu S
    Eur J Med Chem; 2020 Feb; 188():112022. PubMed ID: 31901744
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of 4,5,6,7-Tetrahydrobenzo[1,2-d]thiazoles as Novel DNA Gyrase Inhibitors Targeting the ATP-Binding Site.
    Tomašič T; Katsamakas S; Hodnik Ž; Ilaš J; Brvar M; Solmajer T; Montalvão S; Tammela P; Banjanac M; Ergović G; Anderluh M; Peterlin Mašič L; Kikelj D
    J Med Chem; 2015 Jul; 58(14):5501-21. PubMed ID: 26098163
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of New Schiff Bases Tethered Pyrazole Moiety: Design, Synthesis, Biological Evaluation, and Molecular Docking Study as Dual Targeting DHFR/DNA Gyrase Inhibitors with Immunomodulatory Activity.
    Hassan AS; Askar AA; Naglah AM; Almehizia AA; Ragab A
    Molecules; 2020 Jun; 25(11):. PubMed ID: 32498469
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of novel multi-substituted benzo-indole pyrazole schiff base derivatives with antibacterial activity targeting DNA gyrase.
    Liu H; Chu ZW; Xia DG; Cao HQ; Lv XH
    Bioorg Chem; 2020 Jun; 99():103807. PubMed ID: 32272364
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis, and antibacterial evaluation of new quinoline-1,3,4-oxadiazole and quinoline-1,2,4-triazole hybrids as potential inhibitors of DNA gyrase and topoisomerase IV.
    Hofny HA; Mohamed MFA; Gomaa HAM; Abdel-Aziz SA; Youssif BGM; El-Koussi NA; Aboraia AS
    Bioorg Chem; 2021 Jul; 112():104920. PubMed ID: 33910078
    [TBL] [Abstract][Full Text] [Related]  

  • 19. N-Phenyl-4,5-dibromopyrrolamides and N-Phenylindolamides as ATP Competitive DNA Gyrase B Inhibitors: Design, Synthesis, and Evaluation.
    Zidar N; Macut H; Tomašič T; Brvar M; Montalvão S; Tammela P; Solmajer T; Peterlin Mašič L; Ilaš J; Kikelj D
    J Med Chem; 2015 Aug; 58(15):6179-94. PubMed ID: 26126187
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, green one-pot synthesis and molecular docking study of novel N,N-bis(cyanoacetyl)hydrazines and bis-coumarins as effective inhibitors of DNA gyrase and topoisomerase IV.
    Metwally NH; Abdallah SO; Mohsen MMA
    Bioorg Chem; 2020 Apr; 97():103672. PubMed ID: 32145481
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.