These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

248 related articles for article (PubMed ID: 27841315)

  • 1. HIV-1 Nef sequesters MHC-I intracellularly by targeting early stages of endocytosis and recycling.
    Dirk BS; Pawlak EN; Johnson AL; Van Nynatten LR; Jacob RA; Heit B; Dikeakos JD
    Sci Rep; 2016 Nov; 6():37021. PubMed ID: 27841315
    [TBL] [Abstract][Full Text] [Related]  

  • 2. HIV-1 Nef Antagonizes SERINC5 Restriction by Downregulation of SERINC5 via the Endosome/Lysosome System.
    Shi J; Xiong R; Zhou T; Su P; Zhang X; Qiu X; Li H; Li S; Yu C; Wang B; Ding C; Smithgall TE; Zheng YH
    J Virol; 2018 Jun; 92(11):. PubMed ID: 29514909
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Two Functional Variants of AP-1 Complexes Composed of either γ2 or γ1 Subunits Are Independently Required for Major Histocompatibility Complex Class I Downregulation by HIV-1 Nef.
    Tavares LA; de Carvalho JV; Costa CS; Silveira RM; de Carvalho AN; Donadi EA; daSilva LLP
    J Virol; 2020 Mar; 94(7):. PubMed ID: 31915283
    [TBL] [Abstract][Full Text] [Related]  

  • 4. HIV-1 Nef binds PACS-2 to assemble a multikinase cascade that triggers major histocompatibility complex class I (MHC-I) down-regulation: analysis using short interfering RNA and knock-out mice.
    Atkins KM; Thomas L; Youker RT; Harriff MJ; Pissani F; You H; Thomas G
    J Biol Chem; 2008 Apr; 283(17):11772-84. PubMed ID: 18296443
    [TBL] [Abstract][Full Text] [Related]  

  • 5. HIV-1 Nef-GCC185 interaction regulates assembly of cellular protein complexes at TGN targeting MHC-I downregulation.
    Kumari S; Kumar M; Verma R; Ghosh JK; Tripathi RK
    Life Sci; 2019 Jul; 229():13-20. PubMed ID: 30953643
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes.
    Greenberg ME; Iafrate AJ; Skowronski J
    EMBO J; 1998 May; 17(10):2777-89. PubMed ID: 9582271
    [TBL] [Abstract][Full Text] [Related]  

  • 7. HIV-1 Nef binds a subpopulation of MHC-I throughout its trafficking itinerary and down-regulates MHC-I by perturbing both anterograde and retrograde trafficking.
    Yi L; Rosales T; Rose JJ; Chowdhury B; Knutson JR; Venkatesan S
    J Biol Chem; 2010 Oct; 285(40):30884-905. PubMed ID: 20622010
    [TBL] [Abstract][Full Text] [Related]  

  • 8. HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes.
    Piguet V; Wan L; Borel C; Mangasarian A; Demaurex N; Thomas G; Trono D
    Nat Cell Biol; 2000 Mar; 2(3):163-7. PubMed ID: 10707087
    [TBL] [Abstract][Full Text] [Related]  

  • 9. An interdomain binding site on HIV-1 Nef interacts with PACS-1 and PACS-2 on endosomes to down-regulate MHC-I.
    Dikeakos JD; Thomas L; Kwon G; Elferich J; Shinde U; Thomas G
    Mol Biol Cell; 2012 Jun; 23(11):2184-97. PubMed ID: 22496420
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nef homodimers down-regulate SERINC5 by AP-2-mediated endocytosis to promote HIV-1 infectivity.
    Staudt RP; Smithgall TE
    J Biol Chem; 2020 Nov; 295(46):15540-15552. PubMed ID: 32873704
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Two sorting motifs, a ubiquitination motif and a tyrosine motif, are involved in HIV-1 and simian immunodeficiency virus Nef-mediated receptor endocytosis.
    Cai CY; Zhang X; Sinko PJ; Burakoff SJ; Jin YJ
    J Immunol; 2011 May; 186(10):5807-14. PubMed ID: 21482738
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An MHC-I cytoplasmic domain/HIV-1 Nef fusion protein binds directly to the mu subunit of the AP-1 endosomal coat complex.
    Singh RK; Lau D; Noviello CM; Ghosh P; Guatelli JC
    PLoS One; 2009 Dec; 4(12):e8364. PubMed ID: 20020046
    [TBL] [Abstract][Full Text] [Related]  

  • 13. HIV-1 Nef disrupts MHC-I trafficking by recruiting AP-1 to the MHC-I cytoplasmic tail.
    Roeth JF; Williams M; Kasper MR; Filzen TM; Collins KL
    J Cell Biol; 2004 Dec; 167(5):903-13. PubMed ID: 15569716
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Viral bimolecular fluorescence complementation: a novel tool to study intracellular vesicular trafficking pathways.
    Dirk BS; Jacob RA; Johnson AL; Pawlak EN; Cavanagh PC; Van Nynatten L; Haeryfar SM; Dikeakos JD
    PLoS One; 2015; 10(4):e0125619. PubMed ID: 25915798
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The short cytoplasmic tail of HLA-G determines its resistance to HIV-1 Nef-mediated cell surface downregulation.
    Pizzato N; Derrien M; Lenfant F
    Hum Immunol; 2004 Nov; 65(11):1389-96. PubMed ID: 15556689
    [TBL] [Abstract][Full Text] [Related]  

  • 16. HIV-1 Nef: a master manipulator of the membrane trafficking machinery mediating immune evasion.
    Pawlak EN; Dikeakos JD
    Biochim Biophys Acta; 2015 Apr; 1850(4):733-41. PubMed ID: 25585010
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Small molecule inhibition of HIV-1-induced MHC-I down-regulation identifies a temporally regulated switch in Nef action.
    Dikeakos JD; Atkins KM; Thomas L; Emert-Sedlak L; Byeon IJ; Jung J; Ahn J; Wortman MD; Kukull B; Saito M; Koizumi H; Williamson DM; Hiyoshi M; Barklis E; Takiguchi M; Suzu S; Gronenborn AM; Smithgall TE; Thomas G
    Mol Biol Cell; 2010 Oct; 21(19):3279-92. PubMed ID: 20702582
    [TBL] [Abstract][Full Text] [Related]  

  • 18. HIV-1 Nef targets MHC-I and CD4 for degradation via a final common beta-COP-dependent pathway in T cells.
    Schaefer MR; Wonderlich ER; Roeth JF; Leonard JA; Collins KL
    PLoS Pathog; 2008 Aug; 4(8):e1000131. PubMed ID: 18725938
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CD4 downregulation by the HIV-1 protein Nef reveals distinct roles for the γ1 and γ2 subunits of the AP-1 complex in protein trafficking.
    Tavares LA; da Silva EM; da Silva-Januário ME; Januário YC; de Cavalho JV; Czernisz ÉS; Mardones GA; daSilva LL
    J Cell Sci; 2017 Jan; 130(2):429-443. PubMed ID: 27909244
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Endocytosis of major histocompatibility complex class I molecules is induced by the HIV-1 Nef protein.
    Schwartz O; Maréchal V; Le Gall S; Lemonnier F; Heard JM
    Nat Med; 1996 Mar; 2(3):338-42. PubMed ID: 8612235
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.