BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

351 related articles for article (PubMed ID: 27845898)

  • 1. Transcription factor LSF-DNMT1 complex dissociation by FQI1 leads to aberrant DNA methylation and gene expression.
    Chin HG; Ponnaluri VK; Zhang G; Estève PO; Schaus SE; Hansen U; Pradhan S
    Oncotarget; 2016 Dec; 7(50):83627-83640. PubMed ID: 27845898
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Small molecule inhibitors of Late SV40 Factor (LSF) abrogate hepatocellular carcinoma (HCC): Evaluation using an endogenous HCC model.
    Rajasekaran D; Siddiq A; Willoughby JL; Biagi JM; Christadore LM; Yunes SA; Gredler R; Jariwala N; Robertson CL; Akiel MA; Shen XN; Subler MA; Windle JJ; Schaus SE; Fisher PB; Hansen U; Sarkar D
    Oncotarget; 2015 Sep; 6(28):26266-77. PubMed ID: 26313006
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Antiproliferative small-molecule inhibitors of transcription factor LSF reveal oncogene addiction to LSF in hepatocellular carcinoma.
    Grant TJ; Bishop JA; Christadore LM; Barot G; Chin HG; Woodson S; Kavouris J; Siddiq A; Gredler R; Shen XN; Sherman J; Meehan T; Fitzgerald K; Pradhan S; Briggs LA; Andrews WH; Sarkar D; Schaus SE; Hansen U
    Proc Natl Acad Sci U S A; 2012 Mar; 109(12):4503-8. PubMed ID: 22396589
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting the oncogene LSF with either the small molecule inhibitor FQI1 or siRNA causes mitotic delays with unaligned chromosomes, resulting in cell death or senescence.
    Willoughby JLS; George K; Roberto MP; Chin HG; Stoiber P; Shin H; Pedamallu CS; Schaus SE; Fitzgerald K; Shah J; Hansen U
    BMC Cancer; 2020 Jun; 20(1):552. PubMed ID: 32539694
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The microtubule-associated histone methyltransferase SET8, facilitated by transcription factor LSF, methylates α-tubulin.
    Chin HG; Esteve PO; Ruse C; Lee J; Schaus SE; Pradhan S; Hansen U
    J Biol Chem; 2020 Apr; 295(14):4748-4759. PubMed ID: 32111740
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DNA methyltransferase 1 knockdown induces silenced CDH1 gene reexpression by demethylation of methylated CpG in hepatocellular carcinoma cell line SMMC-7721.
    Fan H; Zhao Z; Quan Y; Xu J; Zhang J; Xie W
    Eur J Gastroenterol Hepatol; 2007 Nov; 19(11):952-61. PubMed ID: 18049164
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The novel mTOR inhibitor Torin-2 induces autophagy and downregulates the expression of UHRF1 to suppress hepatocarcinoma cell growth.
    Wang C; Wang X; Su Z; Fei H; Liu X; Pan Q
    Oncol Rep; 2015 Oct; 34(4):1708-16. PubMed ID: 26239364
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting the PD-L1/DNMT1 axis in acquired resistance to sorafenib in human hepatocellular carcinoma.
    Liu J; Liu Y; Meng L; Liu K; Ji B
    Oncol Rep; 2017 Aug; 38(2):899-907. PubMed ID: 28627705
    [TBL] [Abstract][Full Text] [Related]  

  • 9. SET8 prevents excessive DNA methylation by methylation-mediated degradation of UHRF1 and DNMT1.
    Zhang H; Gao Q; Tan S; You J; Lyu C; Zhang Y; Han M; Chen Z; Li J; Wang H; Liao L; Qin J; Li J; Wong J
    Nucleic Acids Res; 2019 Sep; 47(17):9053-9068. PubMed ID: 31400111
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanistic and biological significance of DNA methyltransferase 1 upregulated by growth factors in human hepatocellular carcinoma.
    Fang QL; Yin YR; Xie CR; Zhang S; Zhao WX; Pan C; Wang XM; Yin ZY
    Int J Oncol; 2015 Feb; 46(2):782-90. PubMed ID: 25420499
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ZNF479 downregulates metallothionein-1 expression by regulating ASH2L and DNMT1 in hepatocellular carcinoma.
    Wu YJ; Ko BS; Liang SM; Lu YJ; Jan YJ; Jiang SS; Shyue SK; Chen L; Liou JY
    Cell Death Dis; 2019 May; 10(6):408. PubMed ID: 31138789
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Epigenetic upregulation of Bak by ZBP-89 inhibits the growth of hepatocellular carcinoma.
    Ye CG; Chen GG; Ho RLK; Merchant JL; He ML; Lai PBS
    Biochim Biophys Acta; 2013 Dec; 1833(12):2970-2979. PubMed ID: 23954442
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The aberrant expression of MEG3 regulated by UHRF1 predicts the prognosis of hepatocellular carcinoma.
    Zhuo H; Tang J; Lin Z; Jiang R; Zhang X; Ji J; Wang P; Sun B
    Mol Carcinog; 2016 Feb; 55(2):209-19. PubMed ID: 25641194
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activated MEK/ERK Pathway Drives Widespread and Coordinated Overexpression of UHRF1 and DNMT1 in Cancer cells.
    Li J; Wang R; Hu X; Gao Y; Wang Z; Li J; Wong J
    Sci Rep; 2019 Jan; 9(1):907. PubMed ID: 30696879
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Factor quinolinone inhibitors disrupt spindles and multiple LSF (TFCP2)-protein interactions in mitosis, including with microtubule-associated proteins.
    Yunes SA; Willoughby JLS; Kwan JH; Biagi JM; Pokharel N; Chin HG; York EA; Su KC; George K; Shah JV; Emili A; Schaus SE; Hansen U
    PLoS One; 2022; 17(6):e0268857. PubMed ID: 35704642
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Enhanced processivity of Dnmt1 by monoubiquitinated histone H3.
    Mishima Y; Brueckner L; Takahashi S; Kawakami T; Otani J; Shinohara A; Takeshita K; Garvilles RG; Watanabe M; Sakai N; Takeshima H; Nachtegael C; Nishiyama A; Nakanishi M; Arita K; Nakashima K; Hojo H; Suetake I
    Genes Cells; 2020 Jan; 25(1):22-32. PubMed ID: 31680384
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SALL3 interacts with DNMT3A and shows the ability to inhibit CpG island methylation in hepatocellular carcinoma.
    Shikauchi Y; Saiura A; Kubo T; Niwa Y; Yamamoto J; Murase Y; Yoshikawa H
    Mol Cell Biol; 2009 Apr; 29(7):1944-58. PubMed ID: 19139273
    [TBL] [Abstract][Full Text] [Related]  

  • 18. UHRF1 is an oncogene that promotes DNA hypomethylation.
    Cancer Discov; 2014 Apr; 4(4):OF9. PubMed ID: 24706678
    [No Abstract]   [Full Text] [Related]  

  • 19. Molecular mechanisms underlying eicosapentaenoic acid inhibition of HDAC1 and DNMT expression and activity in carcinoma cells.
    Ceccarelli V; Ronchetti S; Marchetti MC; Calvitti M; Riccardi C; Grignani F; Vecchini A
    Biochim Biophys Acta Gene Regul Mech; 2020 Feb; 1863(2):194481. PubMed ID: 31923609
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Epigenetic Enhancement of the Post-replicative DNA Mismatch Repair of Mammalian Genomes by a Hemi-
    Wang KY; Chen CC; Tsai SF; Shen CJ
    Sci Rep; 2016 Nov; 6():37490. PubMed ID: 27886214
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.