These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

309 related articles for article (PubMed ID: 27846390)

  • 1. ERK Activation Globally Downregulates miRNAs through Phosphorylating Exportin-5.
    Sun HL; Cui R; Zhou J; Teng KY; Hsiao YH; Nakanishi K; Fassan M; Luo Z; Shi G; Tili E; Kutay H; Lovat F; Vicentini C; Huang HL; Wang SW; Kim T; Zanesi N; Jeon YJ; Lee TJ; Guh JH; Hung MC; Ghoshal K; Teng CM; Peng Y; Croce CM
    Cancer Cell; 2016 Nov; 30(5):723-736. PubMed ID: 27846390
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting Pin1 by inhibitor API-1 regulates microRNA biogenesis and suppresses hepatocellular carcinoma development.
    Pu W; Li J; Zheng Y; Shen X; Fan X; Zhou JK; He J; Deng Y; Liu X; Wang C; Yang S; Chen Q; Liu L; Zhang G; Wei YQ; Peng Y
    Hepatology; 2018 Aug; 68(2):547-560. PubMed ID: 29381806
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pin1 impairs microRNA biogenesis by mediating conformation change of XPO5 in hepatocellular carcinoma.
    Li J; Pu W; Sun HL; Zhou JK; Fan X; Zheng Y; He J; Liu X; Xia Z; Liu L; Wei YQ; Peng Y
    Cell Death Differ; 2018 Sep; 25(9):1612-1624. PubMed ID: 29445125
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Role of Exportin-5 in MicroRNA Biogenesis and Cancer.
    Wu K; He J; Pu W; Peng Y
    Genomics Proteomics Bioinformatics; 2018 Apr; 16(2):120-126. PubMed ID: 29723684
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of 4,6-bis(benzyloxy)-3-phenylbenzofuran as a novel Pin1 inhibitor to suppress hepatocellular carcinoma via upregulating microRNA biogenesis.
    Fan X; He H; Li J; Luo G; Zheng Y; Zhou JK; He J; Pu W; Zhao Y
    Bioorg Med Chem; 2019 Jun; 27(11):2235-2244. PubMed ID: 31027708
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of a Prenylated Flavonol Derivative as a Pin1 Inhibitor to Suppress Hepatocellular Carcinoma by Modulating MicroRNA Biogenesis.
    Zheng Y; Pu W; Li J; Shen X; Zhou Q; Fan X; Yang SY; Yu Y; Chen Q; Wang C; Wu X; Peng Y
    Chem Asian J; 2019 Jan; 14(1):130-134. PubMed ID: 30474357
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Downregulation and tumor-suppressive role of XPO5 in hepatocellular carcinoma.
    Li Y; Wang X; He B; Cai H; Gao Y
    Mol Cell Biochem; 2016 Apr; 415(1-2):197-205. PubMed ID: 27000860
    [TBL] [Abstract][Full Text] [Related]  

  • 8. MicroRNA Biogenesis is Enhanced by Liposome-Encapsulated Pin1 Inhibitor in Hepatocellular Carcinoma.
    Sun D; Tan S; Xiong Y; Pu W; Li J; Wei W; Huang C; Wei YQ; Peng Y
    Theranostics; 2019; 9(16):4704-4716. PubMed ID: 31367251
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells.
    Melo SA; Moutinho C; Ropero S; Calin GA; Rossi S; Spizzo R; Fernandez AF; Davalos V; Villanueva A; Montoya G; Yamamoto H; Schwartz S; Esteller M
    Cancer Cell; 2010 Oct; 18(4):303-15. PubMed ID: 20951941
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Induction of exportin-5 expression during melanoma development supports the cellular behavior of human malignant melanoma cells.
    Ott CA; Linck L; Kremmer E; Meister G; Bosserhoff AK
    Oncotarget; 2016 Sep; 7(38):62292-62304. PubMed ID: 27556702
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The prolyl isomerase Pin1 interacts with and downregulates the activity of AMPK leading to induction of tumorigenicity of hepatocarcinoma cells.
    Khanal P; Kim G; Yun HJ; Cho HG; Choi HS
    Mol Carcinog; 2013 Oct; 52(10):813-23. PubMed ID: 22549912
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MicroRNA-122 confers sorafenib resistance to hepatocellular carcinoma cells by targeting IGF-1R to regulate RAS/RAF/ERK signaling pathways.
    Xu Y; Huang J; Ma L; Shan J; Shen J; Yang Z; Liu L; Luo Y; Yao C; Qian C
    Cancer Lett; 2016 Feb; 371(2):171-81. PubMed ID: 26655273
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Re-evaluation of the roles of DROSHA, Export in 5, and DICER in microRNA biogenesis.
    Kim YK; Kim B; Kim VN
    Proc Natl Acad Sci U S A; 2016 Mar; 113(13):E1881-9. PubMed ID: 26976605
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A precursor microRNA in a cancer cell nucleus: get me out of here!
    Melo SA; Esteller M
    Cell Cycle; 2011 Mar; 10(6):922-5. PubMed ID: 21346411
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nuclear export mediated regulation of microRNAs: potential target for drug intervention.
    Muqbil I; Bao B; Abou-Samra AB; Mohammad RM; Azmi AS
    Curr Drug Targets; 2013 Sep; 14(10):1094-100. PubMed ID: 23834155
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Id1 is down-regulated by hepatocyte growth factor via ERK-dependent and ERK-independent signaling pathways, leading to increased expression of p16INK4a in hepatoma cells.
    Ushio K; Hashimoto T; Kitamura N; Tanaka T
    Mol Cancer Res; 2009 Jul; 7(7):1179-88. PubMed ID: 19567783
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulation of XPO5 phosphorylation by PP2A in hepatocellular carcinoma.
    Li J; Zhou JK; Mu X; Shen S; Xu X; Luo Y; Luo Y; Ming Y; Wu Y; Peng Y
    MedComm (2020); 2022 Jun; 3(2):e125. PubMed ID: 35441157
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MicroRNA-150 suppresses cell proliferation and metastasis in hepatocellular carcinoma by inhibiting the GAB1-ERK axis.
    Sun W; Zhang Z; Wang J; Shang R; Zhou L; Wang X; Duan J; Ruan B; Gao Y; Dai B; Qu S; Liu W; Ding R; Wang L; Wang D; Dou K
    Oncotarget; 2016 Mar; 7(10):11595-608. PubMed ID: 26871477
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comprehensive analysis of microRNA-regulated protein interaction network reveals the tumor suppressive role of microRNA-149 in human hepatocellular carcinoma via targeting AKT-mTOR pathway.
    Zhang Y; Guo X; Xiong L; Yu L; Li Z; Guo Q; Li Z; Li B; Lin N
    Mol Cancer; 2014 Nov; 13():253. PubMed ID: 25424347
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Loss of exosomal miR-320a from cancer-associated fibroblasts contributes to HCC proliferation and metastasis.
    Zhang Z; Li X; Sun W; Yue S; Yang J; Li J; Ma B; Wang J; Yang X; Pu M; Ruan B; Zhao G; Huang Q; Wang L; Tao K; Dou K
    Cancer Lett; 2017 Jul; 397():33-42. PubMed ID: 28288874
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.