These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
138 related articles for article (PubMed ID: 27849360)
1. Robust Reductions of Excess Weight and Hyperphagia by Beloranib in Rat Models of Genetic and Hypothalamic Obesity. Elfers CT; Roth CL Endocrinology; 2017 Jan; 158(1):41-55. PubMed ID: 27849360 [TBL] [Abstract][Full Text] [Related]
2. Preclinical Efficacy and Safety of the Novel Antidiabetic, Antiobesity MetAP2 Inhibitor ZGN-1061. Burkey BF; Hoglen NC; Inskeep P; Wyman M; Hughes TE; Vath JE J Pharmacol Exp Ther; 2018 May; 365(2):301-313. PubMed ID: 29491038 [TBL] [Abstract][Full Text] [Related]
3. Assessment of the anti-obesity effects of the TNP-470 analog, CKD-732. Kim YM; An JJ; Jin YJ; Rhee Y; Cha BS; Lee HC; Lim SK J Mol Endocrinol; 2007 Apr; 38(4):455-65. PubMed ID: 17446235 [TBL] [Abstract][Full Text] [Related]
4. Effects of MetAP2 inhibition on hyperphagia and body weight in Prader-Willi syndrome: A randomized, double-blind, placebo-controlled trial. McCandless SE; Yanovski JA; Miller J; Fu C; Bird LM; Salehi P; Chan CL; Stafford D; Abuzzahab MJ; Viskochil D; Barlow SE; Angulo M; Myers SE; Whitman BY; Styne D; Roof E; Dykens EM; Scheimann AO; Malloy J; Zhuang D; Taylor K; Hughes TE; Kim DD; Butler MG Diabetes Obes Metab; 2017 Dec; 19(12):1751-1761. PubMed ID: 28556449 [TBL] [Abstract][Full Text] [Related]
5. Efficacy and safety of methionine aminopeptidase 2 inhibition in type 2 diabetes: a randomised, placebo-controlled clinical trial. Proietto J; Malloy J; Zhuang D; Arya M; Cohen ND; de Looze FJ; Gilfillan C; Griffin P; Hall S; Nathow T; Oldfield GS; O'Neal DN; Roberts A; Stuckey BGA; Yue D; Taylor K; Kim D Diabetologia; 2018 Sep; 61(9):1918-1922. PubMed ID: 29992370 [TBL] [Abstract][Full Text] [Related]
6. Efficacy and safety of beloranib for weight loss in obese adults: a randomized controlled trial. Kim DD; Krishnarajah J; Lillioja S; de Looze F; Marjason J; Proietto J; Shakib S; Stuckey BGA; Vath JE; Hughes TE Diabetes Obes Metab; 2015 Jun; 17(6):566-572. PubMed ID: 25732625 [TBL] [Abstract][Full Text] [Related]
7. A randomized, placebo-controlled trial of beloranib for the treatment of hypothalamic injury-associated obesity. Shoemaker A; Proietto J; Abuzzahab MJ; Markovic T; Malloy J; Kim DD Diabetes Obes Metab; 2017 Aug; 19(8):1165-1170. PubMed ID: 28261955 [TBL] [Abstract][Full Text] [Related]
8. Hyperphagia in male melanocortin 4 receptor deficient mice promotes growth independently of growth hormone. Tan HY; Steyn FJ; Huang L; Cowley M; Veldhuis JD; Chen C J Physiol; 2016 Dec; 594(24):7309-7326. PubMed ID: 27558671 [TBL] [Abstract][Full Text] [Related]
9. Aspergillus, angiogenesis, and obesity: the story behind beloranib. Howland RH J Psychosoc Nurs Ment Health Serv; 2015 Mar; 53(3):13-6. PubMed ID: 25751824 [TBL] [Abstract][Full Text] [Related]
10. Ascending dose-controlled trial of beloranib, a novel obesity treatment for safety, tolerability, and weight loss in obese women. Hughes TE; Kim DD; Marjason J; Proietto J; Whitehead JP; Vath JE Obesity (Silver Spring); 2013 Sep; 21(9):1782-8. PubMed ID: 23512440 [TBL] [Abstract][Full Text] [Related]
11. Chronic blockade of the melanocortin 4 receptor subtype leads to obesity independently of neuropeptide Y action, with no adverse effects on the gonadotropic and somatotropic axes. Raposinho PD; Castillo E; d'Alleves V; Broqua P; Pralong FP; Aubert ML Endocrinology; 2000 Dec; 141(12):4419-27. PubMed ID: 11108250 [TBL] [Abstract][Full Text] [Related]
12. Diet-genotype interactions in the development of the obese, insulin-resistant phenotype of C57BL/6J mice lacking melanocortin-3 or -4 receptors. Sutton GM; Trevaskis JL; Hulver MW; McMillan RP; Markward NJ; Babin MJ; Meyer EA; Butler AA Endocrinology; 2006 May; 147(5):2183-96. PubMed ID: 16469808 [TBL] [Abstract][Full Text] [Related]
13. Single and multiple dose evaluation of a novel MetAP2 inhibitor: Results of a randomized, double-blind, placebo-controlled clinical trial. Malloy J; Zhuang D; Kim T; Inskeep P; Kim D; Taylor K Diabetes Obes Metab; 2018 Aug; 20(8):1878-1884. PubMed ID: 29577550 [TBL] [Abstract][Full Text] [Related]
14. Introduction of a high-energy diet acutely up-regulates hypothalamic cocaine and amphetamine-regulated transcript, Mc4R and brown adipose tissue uncoupling protein-1 gene expression in male Sprague-Dawley rats. Archer ZA; Rayner DV; Duncan JS; Bell LM; Mercer JG J Neuroendocrinol; 2005 Jan; 17(1):10-7. PubMed ID: 15720470 [TBL] [Abstract][Full Text] [Related]
15. Activation of hypothalamic NPY, AgRP, MC4R, AND IL-6 mRNA levels in young Lewis rats with early-life diet-induced obesity. Stofkova A; Skurlova M; Kiss A; Zelezna B; Zorad S; Jurcovicova J Endocr Regul; 2009 Jul; 43(3):99-106. PubMed ID: 19817504 [TBL] [Abstract][Full Text] [Related]
16. The mahoganoid mutation (Mgrn1md) improves insulin sensitivity in mice with mutations in the melanocortin signaling pathway independently of effects on adiposity. Phan LK; Chung WK; Leibel RL Am J Physiol Endocrinol Metab; 2006 Sep; 291(3):E611-20. PubMed ID: 16638826 [TBL] [Abstract][Full Text] [Related]
17. Analysis of the therapeutic functions of novel melanocortin receptor agonists in MC3R- and MC4R-deficient C57BL/6J mice. Kumar KG; Sutton GM; Dong JZ; Roubert P; Plas P; Halem HA; Culler MD; Yang H; Dixit VD; Butler AA Peptides; 2009 Oct; 30(10):1892-900. PubMed ID: 19646498 [TBL] [Abstract][Full Text] [Related]
18. Food motivated behavior of melanocortin-4 receptor knockout mice under a progressive ratio schedule. Vaughan C; Moore M; Haskell-Luevano C; Rowland NE Peptides; 2006 Nov; 27(11):2829-35. PubMed ID: 16930774 [TBL] [Abstract][Full Text] [Related]
20. The hyperleptinemia and ObRb expression in hyperphagic obese rats. Han Y; Joe Y; Seo E; Lee SR; Park MK; Lee HJ; Kim DK Biochem Biophys Res Commun; 2010 Mar; 394(1):70-4. PubMed ID: 20171169 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]