131 related articles for article (PubMed ID: 2785212)
1. Synthesis of the 2-chloro analogues of 3'-deoxyadenosine, 2',3'-dideoxyadenosine, and 2',3'-didehydro-2',3'-dideoxyadenosine as potential antiviral agents.
Rosowsky A; Solan VC; Sodroski JG; Ruprecht RM
J Med Chem; 1989 May; 32(5):1135-40. PubMed ID: 2785212
[TBL] [Abstract][Full Text] [Related]
2. Investigations on the anti-HIV activity of 2',3'-dideoxyadenosine analogues with modifications in either the pentose or purine moiety. Potent and selective anti-HIV activity of 2,6-diaminopurine 2',3'-dideoxyriboside.
Pauwels R; Baba M; Balzarini J; Herdewijn P; Desmyter J; Robins MJ; Zou RM; Madej D; De Clercq E
Biochem Pharmacol; 1988 Apr; 37(7):1317-25. PubMed ID: 3258516
[TBL] [Abstract][Full Text] [Related]
3. The 2',3'-dideoxyriboside of 2,6-diaminopurine selectively inhibits human immunodeficiency virus (HIV) replication in vitro.
Balzarini J; Pauwels R; Baba M; Robins MJ; Zou RM; Herdewijn P; De Clercq E
Biochem Biophys Res Commun; 1987 May; 145(1):269-76. PubMed ID: 3496089
[TBL] [Abstract][Full Text] [Related]
4. Potent and selective activity of 3'-azido-2,6-diaminopurine-2',3'-dideoxyriboside, 3'-fluoro-2,6-diaminopurine-2',3'-dideoxyriboside, and 3'-fluoro-2',3'-dideoxyguanosine against human immunodeficiency virus.
Balzarini J; Baba M; Pauwels R; Herdewijn P; Wood SG; Robins MJ; de Clercq E
Mol Pharmacol; 1988 Mar; 33(3):243-9. PubMed ID: 3258404
[TBL] [Abstract][Full Text] [Related]
5. The 2',3'-dideoxyriboside of 2,6-diaminopurine and its 2',3'-didehydro derivative inhibit the deamination of 2',3'-dideoxyadenosine, an inhibitor of human immunodeficiency virus (HIV) replication.
Balzarini J; Robins MJ; Zou RM; Herdewijn P; De Clercq E
Biochem Biophys Res Commun; 1987 May; 145(1):277-83. PubMed ID: 3496090
[TBL] [Abstract][Full Text] [Related]
6. Metabolism and anti-human immunodeficiency virus-1 activity of 2-halo-2',3'-dideoxyadenosine derivatives.
Haertle T; Carrera CJ; Wasson DB; Sowers LC; Richman DD; Carson DA
J Biol Chem; 1988 Apr; 263(12):5870-5. PubMed ID: 3258602
[TBL] [Abstract][Full Text] [Related]
7. Potential prodrug derivatives of 2',3'-didehydro-2',3'-dideoxynucleosides. Preparations and antiviral activities.
Mullah KB; Rao TS; Balzarini J; De Clercq E; Bentrude WG
J Med Chem; 1992 Jul; 35(15):2728-35. PubMed ID: 1495007
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and anti-HIV activity of various 2'- and 3'-substituted 2',3'-dideoxyadenosines: a structure-activity analysis.
Herdewijn P; Pauwels R; Baba M; Balzarini J; De Clercq E
J Med Chem; 1987 Nov; 30(11):2131-7. PubMed ID: 3499515
[TBL] [Abstract][Full Text] [Related]
9. Enhancement by 2'-deoxycoformycin of the 5'-phosphorylation and anti-human immunodeficiency virus activity of 2',3'-dideoxyadenosine and 2'-beta-fluoro-2',3'-dideoxyadenosine.
Ahluwalia GS; Cooney DA; Shirasaka T; Mitsuya H; Driscoll JS; Johns DG
Mol Pharmacol; 1994 Nov; 46(5):1002-8. PubMed ID: 7969062
[TBL] [Abstract][Full Text] [Related]
10. Nucleic acid related compounds. 84. Synthesis of 6'-(E and Z)-halohomovinyl derivatives of adenosine, inactivation of S-adenosyl-L-homocysteine hydrolase, and correlation of anticancer and antiviral potencies with enzyme inhibition.
Wnuk SF; Yuan CS; Borchardt RT; Balzarini J; De Clercq E; Robins MJ
J Med Chem; 1994 Oct; 37(21):3579-87. PubMed ID: 7932585
[TBL] [Abstract][Full Text] [Related]
11. Biochemical genetic analysis of 2',3'-dideoxyadenosine metabolism in human T lymphocytes.
Carson DA; Haertle T; Wasson DB; Richman DD
Biochem Biophys Res Commun; 1988 Mar; 151(2):788-93. PubMed ID: 3258154
[TBL] [Abstract][Full Text] [Related]
12. Metabolic pathways for the activation of the antiretroviral agent 2',3'-dideoxyadenosine in human lymphoid cells.
Johnson MA; Ahluwalia G; Connelly MC; Cooney DA; Broder S; Johns DG; Fridland A
J Biol Chem; 1988 Oct; 263(30):15354-7. PubMed ID: 3262616
[TBL] [Abstract][Full Text] [Related]
13. Selective inhibition of human immunodeficiency virus (HIV) by 3'-azido-2', 3'-dideoxyguanosine in vitro.
Baba M; Pauwels R; Balzarini J; Herdewijn P; De Clercq E
Biochem Biophys Res Commun; 1987 Jun; 145(3):1080-6. PubMed ID: 3649230
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and structure-activity relationships of 6-substituted 2',3'-dideoxypurine nucleosides as potential anti-human immunodeficiency virus agents.
Chu CK; Ullas GV; Jeong LS; Ahn SK; Doboszewski B; Lin ZX; Beach JW; Schinazi RF
J Med Chem; 1990 Jun; 33(6):1553-61. PubMed ID: 2342052
[TBL] [Abstract][Full Text] [Related]
15. Permeation and salvage of dideoxyadenosine in mammalian cells.
Plagemann PG; Woffendin C
Mol Pharmacol; 1989 Jul; 36(1):185-92. PubMed ID: 2787472
[TBL] [Abstract][Full Text] [Related]
16. Conversion of 2',3'-dideoxyadenosine (ddA) and 2',3'-didehydro-2',3'-dideoxyadenosine (d4A) to their corresponding aryloxyphosphoramidate derivatives markedly potentiates their activity against human immunodeficiency virus and hepatitis B virus.
Balzarini J; Kruining J; Wedgwood O; Pannecouque C; Aquaro S; Perno CF; Naesens L; Witvrouw M; Heijtink R; De Clercq E; McGuigan C
FEBS Lett; 1997 Jun; 410(2-3):324-8. PubMed ID: 9237655
[TBL] [Abstract][Full Text] [Related]
17. Enhanced stimulation by ribavirin of the 5'-phosphorylation and anti-human immunodeficiency virus activity of purine 2'-beta-fluoro-2',3'-dideoxynucleosides.
Johns DG; Ahluwalia GS; Cooney DA; Mitsuya H; Driscoll JS
Mol Pharmacol; 1993 Sep; 44(3):519-23. PubMed ID: 8371712
[TBL] [Abstract][Full Text] [Related]
18. Phosphoramidate protides of 2',3'-dideoxy-3'-fluoroadenosine and related nucleosides with potent activity against HIV and HBV.
Gudmundsson KS; Daluge SM; Johnson LC; Jansen R; Hazen R; Condreay LD; McGuigan C
Nucleosides Nucleotides Nucleic Acids; 2003 Oct; 22(10):1953-61. PubMed ID: 14609234
[TBL] [Abstract][Full Text] [Related]
19. Enhancement by hydroxyurea of the anti-human immunodeficiency virus type 1 potency of 2'-beta-fluoro-2',3'-dideoxyadenosine in peripheral blood mononuclear cells.
Gao WY; Mitsuya H; Driscoll JS; Johns DG
Biochem Pharmacol; 1995 Jul; 50(2):274-6. PubMed ID: 7632173
[TBL] [Abstract][Full Text] [Related]
20. 2'-Fluoro-2',3'-dideoxyarabinosyladenine: a metabolically stable analogue of the antiretroviral agent 2',3'-dideoxyadenosine.
Masood R; Ahluwalia GS; Cooney DA; Fridland A; Marquez VE; Driscoll JS; Hao Z; Mitsuya H; Perno CF; Broder S
Mol Pharmacol; 1990 Apr; 37(4):590-6. PubMed ID: 2109183
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
