These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. CHIP stabilizes amyloid precursor protein via proteasomal degradation and p53-mediated trans-repression of β-secretase. Singh AK; Pati U Aging Cell; 2015 Aug; 14(4):595-604. PubMed ID: 25773675 [TBL] [Abstract][Full Text] [Related]
3. Control of BACE1 degradation and APP processing by ubiquitin carboxyl-terminal hydrolase L1. Zhang M; Deng Y; Luo Y; Zhang S; Zou H; Cai F; Wada K; Song W J Neurochem; 2012 Mar; 120(6):1129-38. PubMed ID: 22212137 [TBL] [Abstract][Full Text] [Related]
4. Amyloid β-protein oligomers upregulate the β-secretase, BACE1, through a post-translational mechanism involving its altered subcellular distribution in neurons. Mamada N; Tanokashira D; Hosaka A; Kametani F; Tamaoka A; Araki W Mol Brain; 2015 Nov; 8(1):73. PubMed ID: 26552445 [TBL] [Abstract][Full Text] [Related]
5. The circular RNA ciRS-7 promotes APP and BACE1 degradation in an NF-κB-dependent manner. Shi Z; Chen T; Yao Q; Zheng L; Zhang Z; Wang J; Hu Z; Cui H; Han Y; Han X; Zhang K; Hong W FEBS J; 2017 Apr; 284(7):1096-1109. PubMed ID: 28296235 [TBL] [Abstract][Full Text] [Related]
6. Ginsenoside Rg1 attenuates β-amyloid generation via suppressing PPARγ-regulated BACE1 activity in N2a-APP695 cells. Chen LM; Lin ZY; Zhu YG; Lin N; Zhang J; Pan XD; Chen XC Eur J Pharmacol; 2012 Jan; 675(1-3):15-21. PubMed ID: 22166376 [TBL] [Abstract][Full Text] [Related]
7. Amyloid-β₄₂ activates the expression of BACE1 through the JNK pathway. Guglielmotto M; Monteleone D; Giliberto L; Fornaro M; Borghi R; Tamagno E; Tabaton M J Alzheimers Dis; 2011; 27(4):871-83. PubMed ID: 21897006 [TBL] [Abstract][Full Text] [Related]
8. The beta-secretase, BACE: a prime drug target for Alzheimer's disease. Vassar R J Mol Neurosci; 2001 Oct; 17(2):157-70. PubMed ID: 11816789 [TBL] [Abstract][Full Text] [Related]
9. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis. Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065 [TBL] [Abstract][Full Text] [Related]
10. Melatonin regulates the transcription of βAPP-cleaving secretases mediated through melatonin receptors in human neuroblastoma SH-SY5Y cells. Panmanee J; Nopparat C; Chavanich N; Shukla M; Mukda S; Song W; Vincent B; Govitrapong P J Pineal Res; 2015 Oct; 59(3):308-20. PubMed ID: 26123100 [TBL] [Abstract][Full Text] [Related]
11. A genome wide analysis of ubiquitin ligases in APP processing identifies a novel regulator of BACE1 mRNA levels. Espeseth AS; Huang Q; Gates A; Xu M; Yu Y; Simon AJ; Shi XP; Zhang X; Hodor P; Stone DJ; Burchard J; Cavet G; Bartz S; Linsley P; Ray WJ; Hazuda D Mol Cell Neurosci; 2006 Nov; 33(3):227-35. PubMed ID: 16978875 [TBL] [Abstract][Full Text] [Related]
12. ORP150-CHIP chaperone antagonism control BACE1-mediated amyloid processing. Chanana N; Pati U J Cell Biochem; 2018 Jun; 119(6):4615-4626. PubMed ID: 29266373 [TBL] [Abstract][Full Text] [Related]
13. β-amyloid 1-42 induces physiological transcriptional regulation of BACE1. Piccini A; Borghi R; Guglielmotto M; Tamagno E; Cirmena G; Garuti A; Pollero V; Cammarata S; Fornaro M; Messa M; Colombo L; Salmona M; Perry G; Tabaton M J Neurochem; 2012 Sep; 122(5):1023-31. PubMed ID: 22708832 [TBL] [Abstract][Full Text] [Related]
14. Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models. Natunen T; Takalo M; Kemppainen S; Leskelä S; Marttinen M; Kurkinen KMA; Pursiheimo JP; Sarajärvi T; Viswanathan J; Gabbouj S; Solje E; Tahvanainen E; Pirttimäki T; Kurki M; Paananen J; Rauramaa T; Miettinen P; Mäkinen P; Leinonen V; Soininen H; Airenne K; Tanzi RE; Tanila H; Haapasalo A; Hiltunen M Neurobiol Dis; 2016 Jan; 85():187-205. PubMed ID: 26563932 [TBL] [Abstract][Full Text] [Related]
15. MicroRNA-384 regulates both amyloid precursor protein and β-secretase expression and is a potential biomarker for Alzheimer's disease. Liu CG; Wang JL; Li L; Wang PC Int J Mol Med; 2014 Jul; 34(1):160-6. PubMed ID: 24827165 [TBL] [Abstract][Full Text] [Related]
16. In vivo beta-secretase 1 inhibition leads to brain Abeta lowering and increased alpha-secretase processing of amyloid precursor protein without effect on neuregulin-1. Sankaranarayanan S; Price EA; Wu G; Crouthamel MC; Shi XP; Tugusheva K; Tyler KX; Kahana J; Ellis J; Jin L; Steele T; Stachel S; Coburn C; Simon AJ J Pharmacol Exp Ther; 2008 Mar; 324(3):957-69. PubMed ID: 18156464 [TBL] [Abstract][Full Text] [Related]
17. Palmitate Increases β-site AβPP-Cleavage Enzyme 1 Activity and Amyloid-β Genesis by Evoking Endoplasmic Reticulum Stress and Subsequent C/EBP Homologous Protein Activation. Marwarha G; Rostad S; Lilek J; Kleinjan M; Schommer J; Ghribi O J Alzheimers Dis; 2017; 57(3):907-925. PubMed ID: 28304295 [TBL] [Abstract][Full Text] [Related]
18. BACE1: the beta-secretase enzyme in Alzheimer's disease. Vassar R J Mol Neurosci; 2004; 23(1-2):105-14. PubMed ID: 15126696 [TBL] [Abstract][Full Text] [Related]
19. Auraptene increases the production of amyloid-β via c-Jun N-terminal kinase-dependent activation of γ-secretase. Jung CG; Uhm KO; Horike H; Kim MJ; Misumi S; Ishida A; Ueda Y; Choi EK; Kim YS; Michikawa M; Hida H J Alzheimers Dis; 2015; 43(4):1215-28. PubMed ID: 25147119 [TBL] [Abstract][Full Text] [Related]
20. Aβ-induced Ca(2+) influx regulates astrocytic BACE1 expression via calcineurin/NFAT4 signals. Jin SM; Cho HJ; Kim YW; Hwang JY; Mook-Jung I Biochem Biophys Res Commun; 2012 Aug; 425(3):649-55. PubMed ID: 22846573 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]