BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 27854215)

  • 1. Characterization of New Transgenic Mouse Models for Two Charcot-Marie-Tooth-Causing HspB1 Mutations using the Rosa26 Locus.
    Bouhy D; Geuens T; De Winter V; Almeida-Souza L; Katona I; Weis J; Hochepied T; Goossens S; Haigh JJ; Janssens S; Timmerman V
    J Neuromuscul Dis; 2016 May; 3(2):183-200. PubMed ID: 27854215
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy.
    Evgrafov OV; Mersiyanova I; Irobi J; Van Den Bosch L; Dierick I; Leung CL; Schagina O; Verpoorten N; Van Impe K; Fedotov V; Dadali E; Auer-Grumbach M; Windpassinger C; Wagner K; Mitrovic Z; Hilton-Jones D; Talbot K; Martin JJ; Vasserman N; Tverskaya S; Polyakov A; Liem RK; Gettemans J; Robberecht W; De Jonghe P; Timmerman V
    Nat Genet; 2004 Jun; 36(6):602-6. PubMed ID: 15122254
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Charcot-Marie-Tooth 2F (Hsp27 mutations): A review.
    Schwartz NU
    Neurobiol Dis; 2019 Oct; 130():104505. PubMed ID: 31212070
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutant HSPB1 overexpression in neurons is sufficient to cause age-related motor neuronopathy in mice.
    Srivastava AK; Renusch SR; Naiman NE; Gu S; Sneh A; Arnold WD; Sahenk Z; Kolb SJ
    Neurobiol Dis; 2012 Aug; 47(2):163-73. PubMed ID: 22521462
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Disruption of neurofilament network with aggregation of light neurofilament protein: a common pathway leading to motor neuron degeneration due to Charcot-Marie-Tooth disease-linked mutations in NFL and HSPB1.
    Zhai J; Lin H; Julien JP; Schlaepfer WW
    Hum Mol Genet; 2007 Dec; 16(24):3103-16. PubMed ID: 17881652
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A novel HSPB1
    Espinoza KS; Hermanson KN; Beard CA; Schwartz NU; Snider JM; Low BE; Wiles MV; Hannun YA; Obeid LM; Snider AJ
    Prostaglandins Other Lipid Mediat; 2023 Dec; 169():106769. PubMed ID: 37625781
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutant HSPB1 causes loss of translational repression by binding to PCBP1, an RNA binding protein with a possible role in neurodegenerative disease.
    Geuens T; De Winter V; Rajan N; Achsel T; Mateiu L; Almeida-Souza L; Asselbergh B; Bouhy D; Auer-Grumbach M; Bagni C; Timmerman V
    Acta Neuropathol Commun; 2017 Jan; 5(1):5. PubMed ID: 28077174
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Increased monomerization of mutant HSPB1 leads to protein hyperactivity in Charcot-Marie-Tooth neuropathy.
    Almeida-Souza L; Goethals S; de Winter V; Dierick I; Gallardo R; Van Durme J; Irobi J; Gettemans J; Rousseau F; Schymkowitz J; Timmerman V; Janssens S
    J Biol Chem; 2010 Apr; 285(17):12778-86. PubMed ID: 20178975
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Overexpression of mutant HSP27 causes axonal neuropathy in mice.
    Lee J; Jung SC; Joo J; Choi YR; Moon HW; Kwak G; Yeo HK; Lee JS; Ahn HJ; Jung N; Hwang S; Rheey J; Woo SY; Kim JY; Hong YB; Choi BO
    J Biomed Sci; 2015 Jun; 22(1):43. PubMed ID: 26141737
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A novel p.T139M mutation in HSPB1 highlighting the phenotypic spectrum in a family.
    Amornvit J; Yalvac ME; Chen L; Sahenk Z
    Brain Behav; 2017 Aug; 7(8):e00774. PubMed ID: 28828227
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Clinical and genetic features of Charcot-Marie-Tooth disease 2F and hereditary motor neuropathy 2B in Japan.
    Tanabe H; Higuchi Y; Yuan JH; Hashiguchi A; Yoshimura A; Ishihara S; Nozuma S; Okamoto Y; Matsuura E; Ishiura H; Mitsui J; Takashima R; Kokubun N; Maeda K; Asano Y; Sunami Y; Kono Y; Ishigaki Y; Yanamoto S; Fukae J; Kida H; Morita M; Tsuji S; Takashima H
    J Peripher Nerv Syst; 2018 Mar; 23(1):40-48. PubMed ID: 29381233
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pilot phenotype and natural history study of hereditary neuropathies caused by mutations in the HSPB1 gene.
    Rossor AM; Morrow JM; Polke JM; Murphy SM; Houlden H; ; Laura M; Manji H; Blake J; Reilly MM
    Neuromuscul Disord; 2017 Jan; 27(1):50-56. PubMed ID: 27816334
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutations in the HSP27 (HSPB1) gene cause dominant, recessive, and sporadic distal HMN/CMT type 2.
    Houlden H; Laura M; Wavrant-De Vrièze F; Blake J; Wood N; Reilly MM
    Neurology; 2008 Nov; 71(21):1660-8. PubMed ID: 18832141
    [TBL] [Abstract][Full Text] [Related]  

  • 14. HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1-induced Charcot-Marie-Tooth disease.
    d'Ydewalle C; Krishnan J; Chiheb DM; Van Damme P; Irobi J; Kozikowski AP; Vanden Berghe P; Timmerman V; Robberecht W; Van Den Bosch L
    Nat Med; 2011 Jul; 17(8):968-74. PubMed ID: 21785432
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mitochondrial deficits and abnormal mitochondrial retrograde axonal transport play a role in the pathogenesis of mutant Hsp27-induced Charcot Marie Tooth Disease.
    Kalmar B; Innes A; Wanisch K; Kolaszynska AK; Pandraud A; Kelly G; Abramov AY; Reilly MM; Schiavo G; Greensmith L
    Hum Mol Genet; 2017 Sep; 26(17):3313-3326. PubMed ID: 28595321
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Charcot-Marie-Tooth causing HSPB1 mutations increase Cdk5-mediated phosphorylation of neurofilaments.
    Holmgren A; Bouhy D; De Winter V; Asselbergh B; Timmermans JP; Irobi J; Timmerman V
    Acta Neuropathol; 2013 Jul; 126(1):93-108. PubMed ID: 23728742
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A Charcot-Marie-Tooth-Causing Mutation in HSPB1 Decreases Cell Adaptation to Repeated Stress by Disrupting Autophagic Clearance of Misfolded Proteins.
    Zhang X; Qiao Y; Han R; Gao Y; Yang X; Zhang Y; Wan Y; Yu W; Pan X; Xing J
    Cells; 2022 Sep; 11(18):. PubMed ID: 36139461
    [TBL] [Abstract][Full Text] [Related]  

  • 18. HSPB1 mutations causing hereditary neuropathy in humans disrupt non-cell autonomous protection of motor neurons.
    Heilman PL; Song S; Miranda CJ; Meyer K; Srivastava AK; Knapp A; Wier CG; Kaspar BK; Kolb SJ
    Exp Neurol; 2017 Nov; 297():101-109. PubMed ID: 28797631
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutations in heat shock protein beta-1 (HSPB1) are associated with a range of clinical phenotypes related to different patterns of motor neuron dysfunction: A case series.
    Katz M; Davis M; Garton FC; Henderson R; Bharti V; Wray N; McCombe P
    J Neurol Sci; 2020 Jun; 413():116809. PubMed ID: 32334137
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Small Heat Shock Proteins and Distal Hereditary Neuropathies.
    Nefedova VV; Muranova LK; Sudnitsyna MV; Ryzhavskaya AS; Gusev NB
    Biochemistry (Mosc); 2015 Dec; 80(13):1734-47. PubMed ID: 26878578
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.