BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

394 related articles for article (PubMed ID: 27863149)

  • 1. Expression of Cyclic GMP-AMP Synthase in Patients With Systemic Lupus Erythematosus.
    An J; Durcan L; Karr RM; Briggs TA; Rice GI; Teal TH; Woodward JJ; Elkon KB
    Arthritis Rheumatol; 2017 Apr; 69(4):800-807. PubMed ID: 27863149
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of Cyclic GMP-AMP Synthase Using a Novel Antimalarial Drug Derivative in Trex1-Deficient Mice.
    An J; Woodward JJ; Lai W; Minie M; Sun X; Tanaka L; Snyder JM; Sasaki T; Elkon KB
    Arthritis Rheumatol; 2018 Nov; 70(11):1807-1819. PubMed ID: 29781188
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Apoptosis-derived membrane vesicles drive the cGAS-STING pathway and enhance type I IFN production in systemic lupus erythematosus.
    Kato Y; Park J; Takamatsu H; Konaka H; Aoki W; Aburaya S; Ueda M; Nishide M; Koyama S; Hayama Y; Kinehara Y; Hirano T; Shima Y; Narazaki M; Kumanogoh A
    Ann Rheum Dis; 2018 Oct; 77(10):1507-1515. PubMed ID: 29945921
    [TBL] [Abstract][Full Text] [Related]  

  • 4. UXT attenuates the CGAS-STING1 signaling by targeting STING1 for autophagic degradation.
    Pan M; Yin Y; Hu T; Wang X; Jia T; Sun J; Wang Q; Meng W; Zhu J; Dai C; Hu H; Wang C
    Autophagy; 2023 Feb; 19(2):440-456. PubMed ID: 35543189
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Association of Abnormal Elevations in IFIT3 With Overactive Cyclic GMP-AMP Synthase/Stimulator of Interferon Genes Signaling in Human Systemic Lupus Erythematosus Monocytes.
    Wang J; Dai M; Cui Y; Hou G; Deng J; Gao X; Liao Z; Liu Y; Meng Y; Wu L; Yao C; Wang Y; Qian J; Guo Q; Ding H; Qu B; Shen N
    Arthritis Rheumatol; 2018 Dec; 70(12):2036-2045. PubMed ID: 29806091
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The role of cyclic GMP-AMP synthase and Interferon-I-inducible protein 16 as candidatebiomarkers of systemic lupus erythematosus.
    Fu Q; He Q; Dong Q; Xie J; Geng Y; Han H; Huang Y; Lu J; Zeng Z; Wang W; Chen K; Zhan X
    Clin Chim Acta; 2022 Jan; 524():69-77. PubMed ID: 34742679
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases.
    Gao D; Li T; Li XD; Chen X; Li QZ; Wight-Carter M; Chen ZJ
    Proc Natl Acad Sci U S A; 2015 Oct; 112(42):E5699-705. PubMed ID: 26371324
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CSNK1A1/CK1α suppresses autoimmunity by restraining the CGAS-STING1 signaling.
    Pan M; Hu T; Lyu J; Yin Y; Sun J; Wang Q; Xu L; Hu H; Wang C
    Autophagy; 2024 Feb; 20(2):311-328. PubMed ID: 37723657
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of mTOR suppresses IFNα production and the STING pathway in monocytes from systemic lupus erythematosus patients.
    Murayama G; Chiba A; Kuga T; Makiyama A; Yamaji K; Tamura N; Miyake S
    Rheumatology (Oxford); 2020 Oct; 59(10):2992-3002. PubMed ID: 32160289
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Suppressive oligodeoxynucleotides containing TTAGGG motifs inhibit cGAS activation in human monocytes.
    Steinhagen F; Zillinger T; Peukert K; Fox M; Thudium M; Barchet W; Putensen C; Klinman D; Latz E; Bode C
    Eur J Immunol; 2018 Apr; 48(4):605-611. PubMed ID: 29215161
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Small molecule inhibition of human cGAS reduces total cGAMP output and cytokine expression in cells.
    Wiser C; Kim B; Vincent J; Ascano M
    Sci Rep; 2020 May; 10(1):7604. PubMed ID: 32371942
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Priming of the cGAS-STING-TBK1 Pathway Enhances LPS-Induced Release of Type I Interferons.
    Tesser A; Piperno GM; Pin A; Piscianz E; Boz V; Benvenuti F; Tommasini A
    Cells; 2021 Apr; 10(4):. PubMed ID: 33916318
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The regional function of cGAS/STING signal in multiple organs: One of culprit behind systemic lupus erythematosus?
    Ding L; Dong G; Zhang D; Ni Y; Hou Y
    Med Hypotheses; 2015 Dec; 85(6):846-9. PubMed ID: 26464144
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Compound C Reducing Interferon Expression by Inhibiting cGAMP Accumulation.
    Lai J; Luo X; Tian S; Zhang X; Huang S; Wang H; Li Q; Cai S; Chen Q
    Front Pharmacol; 2020; 11():88. PubMed ID: 32180716
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Emerging role of the cGAS-STING signaling pathway in autoimmune diseases: Biologic function, mechanisms and clinical prospection.
    Hu Y; Chen B; Yang F; Su Y; Yang D; Yao Y; Wang S; Wu Y; Tao L; Xu T
    Autoimmun Rev; 2022 Sep; 21(9):103155. PubMed ID: 35902046
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Toll-Like Receptor (TLR) Signaling Enables Cyclic GMP-AMP Synthase (cGAS) Sensing of HIV-1 Infection in Macrophages.
    Siddiqui MA; Yamashita M
    mBio; 2021 Dec; 12(6):e0281721. PubMed ID: 34844429
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cyclic GMP-AMP Synthase Is the Cytosolic Sensor of
    Gallego-Marin C; Schrum JE; Andrade WA; Shaffer SA; Giraldo LF; Lasso AM; Kurt-Jones EA; Fitzgerald KA; Golenbock DT
    J Immunol; 2018 Jan; 200(2):768-774. PubMed ID: 29212905
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.
    Hall J; Ralph EC; Shanker S; Wang H; Byrnes LJ; Horst R; Wong J; Brault A; Dumlao D; Smith JF; Dakin LA; Schmitt DC; Trujillo J; Vincent F; Griffor M; Aulabaugh AE
    Protein Sci; 2017 Dec; 26(12):2367-2380. PubMed ID: 28940468
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of Cyclin-Dependent Kinase 1 as a Novel Regulator of Type I Interferon Signaling in Systemic Lupus Erythematosus.
    Wu L; Qin Y; Xia S; Dai M; Han X; Wu Y; Zhang X; Ma J; Wang Y; Tang Y; Liu Z; Zhu W; Jallal B; Yao Y; Qu B; Shen N
    Arthritis Rheumatol; 2016 May; 68(5):1222-32. PubMed ID: 26663909
    [TBL] [Abstract][Full Text] [Related]  

  • 20. cGAS deficiency enhances inflammasome activation in macrophages and inflammatory pathology in pristane-induced lupus.
    Kumpunya S; Thim-Uam A; Thumarat C; Leelahavanichkul A; Kalpongnukul N; Chantaravisoot N; Pisitkun T; Pisitkun P
    Front Immunol; 2022; 13():1010764. PubMed ID: 36591278
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.