These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

213 related articles for article (PubMed ID: 27863716)

  • 1. Antibodies against the C-terminus of α-synuclein modulate its fibrillation.
    Sahin C; Lorenzen N; Lemminger L; Christiansen G; Møller IM; Vesterager LB; Pedersen LØ; Fog K; Kallunki P; Otzen DE
    Biophys Chem; 2017 Jan; 220():34-41. PubMed ID: 27863716
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Scutellarin inhibits the uninduced and metal-induced aggregation of α-Synuclein and disaggregates preformed fibrils: implications for Parkinson's disease.
    Zaidi FK; Deep S
    Biochem J; 2020 Feb; 477(3):645-670. PubMed ID: 31939603
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Complexation of NAC-Derived Peptide Ligands with the C-Terminus of α-Synuclein Accelerates Its Aggregation.
    Jha NN; Ranganathan S; Kumar R; Mehra S; Panigrahi R; Navalkar A; Ghosh D; Kumar A; Padinhateeri R; Maji SK
    Biochemistry; 2018 Feb; 57(5):791-804. PubMed ID: 29286644
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Paradoxical Effect of Trehalose on the Aggregation of α-Synuclein: Expedites Onset of Aggregation yet Reduces Fibril Load.
    Katyal N; Agarwal M; Sen R; Kumar V; Deep S
    ACS Chem Neurosci; 2018 Jun; 9(6):1477-1491. PubMed ID: 29601727
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles.
    Doucet M; El-Turabi A; Zabel F; Hunn BHM; Bengoa-Vergniory N; Cioroch M; Ramm M; Smith AM; Gomes AC; Cabral de Miranda G; Wade-Martins R; Bachmann MF
    PLoS One; 2017; 12(8):e0181844. PubMed ID: 28797124
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The N-terminus of α-synuclein is essential for both monomeric and oligomeric interactions with membranes.
    Lorenzen N; Lemminger L; Pedersen JN; Nielsen SB; Otzen DE
    FEBS Lett; 2014 Jan; 588(3):497-502. PubMed ID: 24374342
    [TBL] [Abstract][Full Text] [Related]  

  • 7. α-Synucleins from Animal Species Show Low Fibrillation Propensities and Weak Oligomer Membrane Disruption.
    Sahin C; Kjær L; Christensen MS; N Pedersen J; Christiansen G; Pérez AW; Møller IM; Enghild JJ; Pedersen JS; Larsen K; Otzen DE
    Biochemistry; 2018 Aug; 57(34):5145-5158. PubMed ID: 30067901
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Isolation of a human single chain antibody fragment against oligomeric alpha-synuclein that inhibits aggregation and prevents alpha-synuclein-induced toxicity.
    Emadi S; Barkhordarian H; Wang MS; Schulz P; Sierks MR
    J Mol Biol; 2007 May; 368(4):1132-44. PubMed ID: 17391701
    [TBL] [Abstract][Full Text] [Related]  

  • 9. α-synuclein oligomers and fibrils: a spectrum of species, a spectrum of toxicities.
    Alam P; Bousset L; Melki R; Otzen DE
    J Neurochem; 2019 Sep; 150(5):522-534. PubMed ID: 31254394
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The C-terminal α-helices of mammalian Hsc70 play a critical role in the stabilization of α-synuclein binding and inhibition of aggregation.
    Chaari A; Eliezer D; Ladjimi M
    Int J Biol Macromol; 2016 Feb; 83():433-41. PubMed ID: 26601760
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Insight into the molecular mechanism underlying the inhibition of α-synuclein aggregation by hydroxytyrosol.
    Palazzi L; Leri M; Cesaro S; Stefani M; Bucciantini M; Polverino de Laureto P
    Biochem Pharmacol; 2020 Mar; 173():113722. PubMed ID: 31756328
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Polyphenols in combination with β-cyclodextrin can inhibit and disaggregate α-synuclein amyloids under cell mimicking conditions: A promising therapeutic alternative.
    Gautam S; Karmakar S; Batra R; Sharma P; Pradhan P; Singh J; Kundu B; Chowdhury PK
    Biochim Biophys Acta Proteins Proteom; 2017 May; 1865(5):589-603. PubMed ID: 28238838
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Impact of Tyr to Ala mutations on alpha-synuclein fibrillation and structural properties.
    Ulrih NP; Barry CH; Fink AL
    Biochim Biophys Acta; 2008 Oct; 1782(10):581-5. PubMed ID: 18692132
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antibodies and α-synuclein: What to target against Parkinson's Disease?
    Otzen DE
    Biochim Biophys Acta Proteins Proteom; 2024 Feb; 1872(2):140943. PubMed ID: 37783321
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Development of an aggregate-selective, human-derived α-synuclein antibody BIIB054 that ameliorates disease phenotypes in Parkinson's disease models.
    Weihofen A; Liu Y; Arndt JW; Huy C; Quan C; Smith BA; Baeriswyl JL; Cavegn N; Senn L; Su L; Marsh G; Auluck PK; Montrasio F; Nitsch RM; Hirst WD; Cedarbaum JM; Pepinsky RB; Grimm J; Weinreb PH
    Neurobiol Dis; 2019 Apr; 124():276-288. PubMed ID: 30381260
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Heme Stabilization of α-Synuclein Oligomers during Amyloid Fibril Formation.
    Hayden EY; Kaur P; Williams TL; Matsui H; Yeh SR; Rousseau DL
    Biochemistry; 2015 Aug; 54(30):4599-610. PubMed ID: 26161848
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Immunotherapy targeting α-synuclein, with relevance for future treatment of Parkinson's disease and other Lewy body disorders.
    Lindström V; Ihse E; Fagerqvist T; Bergström J; Nordström E; Möller C; Lannfelt L; Ingelsson M
    Immunotherapy; 2014; 6(2):141-53. PubMed ID: 24491088
    [TBL] [Abstract][Full Text] [Related]  

  • 18. High Selectivity and Sensitivity of Oligomeric p-Phenylene Ethynylenes for Detecting Fibrillar and Prefibrillar Amyloid Protein Aggregates.
    Fanni AM; Monge FA; Lin CY; Thapa A; Bhaskar K; Whitten DG; Chi EY
    ACS Chem Neurosci; 2019 Mar; 10(3):1813-1825. PubMed ID: 30657326
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A protein-chameleon: conformational plasticity of alpha-synuclein, a disordered protein involved in neurodegenerative disorders.
    Uversky VN
    J Biomol Struct Dyn; 2003 Oct; 21(2):211-34. PubMed ID: 12956606
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Brain propagation of transduced α-synuclein involves non-fibrillar protein species and is enhanced in α-synuclein null mice.
    Helwig M; Klinkenberg M; Rusconi R; Musgrove RE; Majbour NK; El-Agnaf OM; Ulusoy A; Di Monte DA
    Brain; 2016 Mar; 139(Pt 3):856-70. PubMed ID: 26719384
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.