BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

321 related articles for article (PubMed ID: 27865806)

  • 1. Ikaros: Exploiting and targeting the hematopoietic stem cell niche in B-progenitor acute lymphoblastic leukemia.
    Churchman ML; Mullighan CG
    Exp Hematol; 2017 Feb; 46():1-8. PubMed ID: 27865806
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Germline Genetic IKZF1 Variation and Predisposition to Childhood Acute Lymphoblastic Leukemia.
    Churchman ML; Qian M; Te Kronnie G; Zhang R; Yang W; Zhang H; Lana T; Tedrick P; Baskin R; Verbist K; Peters JL; Devidas M; Larsen E; Moore IM; Gu Z; Qu C; Yoshihara H; Porter SN; Pruett-Miller SM; Wu G; Raetz E; Martin PL; Bowman WP; Winick N; Mardis E; Fulton R; Stanulla M; Evans WE; Relling MV; Pui CH; Hunger SP; Loh ML; Handgretinger R; Nichols KE; Yang JJ; Mullighan CG
    Cancer Cell; 2018 May; 33(5):937-948.e8. PubMed ID: 29681510
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Efficacy of Retinoids in IKZF1-Mutated BCR-ABL1 Acute Lymphoblastic Leukemia.
    Churchman ML; Low J; Qu C; Paietta EM; Kasper LH; Chang Y; Payne-Turner D; Althoff MJ; Song G; Chen SC; Ma J; Rusch M; McGoldrick D; Edmonson M; Gupta P; Wang YD; Caufield W; Freeman B; Li L; Panetta JC; Baker S; Yang YL; Roberts KG; McCastlain K; Iacobucci I; Peters JL; Centonze VE; Notta F; Dobson SM; Zandi S; Dick JE; Janke L; Peng J; Kodali K; Pagala V; Min J; Mayasundari A; Williams RT; Willman CL; Rowe J; Luger S; Dickins RA; Guy RK; Chen T; Mullighan CG
    Cancer Cell; 2015 Sep; 28(3):343-56. PubMed ID: 26321221
    [TBL] [Abstract][Full Text] [Related]  

  • 4. IKZF1 and CRLF2 gene alterations correlate with poor prognosis in Japanese BCR-ABL1-negative high-risk B-cell precursor acute lymphoblastic leukemia.
    Yamashita Y; Shimada A; Yamada T; Yamaji K; Hori T; Tsurusawa M; Watanabe A; Kikuta A; Asami K; Saito AM; Horibe K
    Pediatr Blood Cancer; 2013 Oct; 60(10):1587-92. PubMed ID: 23804397
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synergism of FAK and tyrosine kinase inhibition in Ph
    Churchman ML; Evans K; Richmond J; Robbins A; Jones L; Shapiro IM; Pachter JA; Weaver DT; Houghton PJ; Smith MA; Lock RB; Mullighan CG
    JCI Insight; 2016; 1(4):. PubMed ID: 27123491
    [TBL] [Abstract][Full Text] [Related]  

  • 6. BCR-ABL1 induces aberrant splicing of IKAROS and lineage infidelity in pre-B lymphoblastic leukemia cells.
    Klein F; Feldhahn N; Herzog S; Sprangers M; Mooster JL; Jumaa H; Müschen M
    Oncogene; 2006 Feb; 25(7):1118-24. PubMed ID: 16205638
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The biology of Philadelphia chromosome-like ALL.
    Roberts KG
    Best Pract Res Clin Haematol; 2017 Sep; 30(3):212-221. PubMed ID: 29050694
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia.
    Mullighan CG; Su X; Zhang J; Radtke I; Phillips LA; Miller CB; Ma J; Liu W; Cheng C; Schulman BA; Harvey RC; Chen IM; Clifford RJ; Carroll WL; Reaman G; Bowman WP; Devidas M; Gerhard DS; Yang W; Relling MV; Shurtleff SA; Campana D; Borowitz MJ; Pui CH; Smith M; Hunger SP; Willman CL; Downing JR;
    N Engl J Med; 2009 Jan; 360(5):470-80. PubMed ID: 19129520
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The many faces of IKZF1 in B-cell precursor acute lymphoblastic leukemia.
    Marke R; van Leeuwen FN; Scheijen B
    Haematologica; 2018 Apr; 103(4):565-574. PubMed ID: 29519871
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ikaros family zinc-finger 1 mutation is an independent factor for the poor prognosis of adult B-cell acute lymphoblastic leukemia, and allogeneic hematopoietic stem cell transplantation can improve clinical outcomes.
    Tang S; Shen H; Qu C; Dai H; Zhu X; Xue S; Ding Z; Lu J; Wu D; Tang X
    Bone Marrow Transplant; 2019 Feb; 54(2):236-243. PubMed ID: 29942002
    [TBL] [Abstract][Full Text] [Related]  

  • 11. IKAROS deletions dictate a unique gene expression signature in patients with adult B-cell acute lymphoblastic leukemia.
    Iacobucci I; Iraci N; Messina M; Lonetti A; Chiaretti S; Valli E; Ferrari A; Papayannidis C; Paoloni F; Vitale A; Storlazzi CT; Ottaviani E; Guadagnuolo V; Durante S; Vignetti M; Soverini S; Pane F; Foà R; Baccarani M; Müschen M; Perini G; Martinelli G
    PLoS One; 2012; 7(7):e40934. PubMed ID: 22848414
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting casein kinase II restores Ikaros tumor suppressor activity and demonstrates therapeutic efficacy in high-risk leukemia.
    Song C; Gowda C; Pan X; Ding Y; Tong Y; Tan BH; Wang H; Muthusami S; Ge Z; Sachdev M; Amin SG; Desai D; Gowda K; Gowda R; Robertson GP; Schjerven H; Muschen M; Payne KJ; Dovat S
    Blood; 2015 Oct; 126(15):1813-22. PubMed ID: 26219304
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tumor suppressors BTG1 and IKZF1 cooperate during mouse leukemia development and increase relapse risk in B-cell precursor acute lymphoblastic leukemia patients.
    Scheijen B; Boer JM; Marke R; Tijchon E; van Ingen Schenau D; Waanders E; van Emst L; van der Meer LT; Pieters R; Escherich G; Horstmann MA; Sonneveld E; Venn N; Sutton R; Dalla-Pozza L; Kuiper RP; Hoogerbrugge PM; den Boer ML; van Leeuwen FN
    Haematologica; 2017 Mar; 102(3):541-551. PubMed ID: 27979924
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ikaros deletions in BCR-ABL-negative childhood acute lymphoblastic leukemia are associated with a distinct gene expression signature but do not result in intrinsic chemoresistance.
    Vitanza NA; Zaky W; Blum R; Meyer JA; Wang J; Bhatla T; Morrison DJ; Raetz EA; Carroll WL
    Pediatr Blood Cancer; 2014 Oct; 61(10):1779-85. PubMed ID: 24976218
    [TBL] [Abstract][Full Text] [Related]  

  • 15. BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros.
    Mullighan CG; Miller CB; Radtke I; Phillips LA; Dalton J; Ma J; White D; Hughes TP; Le Beau MM; Pui CH; Relling MV; Shurtleff SA; Downing JR
    Nature; 2008 May; 453(7191):110-4. PubMed ID: 18408710
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transcriptional Regulation of JARID1B/KDM5B Histone Demethylase by Ikaros, Histone Deacetylase 1 (HDAC1), and Casein Kinase 2 (CK2) in B-cell Acute Lymphoblastic Leukemia.
    Wang H; Song C; Ding Y; Pan X; Ge Z; Tan BH; Gowda C; Sachdev M; Muthusami S; Ouyang H; Lai L; Francis OL; Morris CL; Abdel-Azim H; Dorsam G; Xiang M; Payne KJ; Dovat S
    J Biol Chem; 2016 Feb; 291(8):4004-18. PubMed ID: 26655717
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: implications for a new mechanism of resistance.
    Iacobucci I; Lonetti A; Messa F; Cilloni D; Arruga F; Ottaviani E; Paolini S; Papayannidis C; Piccaluga PP; Giannoulia P; Soverini S; Amabile M; Poerio A; Saglio G; Pane F; Berton G; Baruzzi A; Vitale A; Chiaretti S; Perini G; Foà R; Baccarani M; Martinelli G
    Blood; 2008 Nov; 112(9):3847-55. PubMed ID: 18650450
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting of heme oxygenase-1 attenuates the negative impact of Ikaros isoform 6 in adult BCR-ABL1-positive B-ALL.
    Lin X; Zou X; Wang Z; Fang Q; Chen S; Huang J; Zhe N; Yu M; Zhang Y; Wang J
    Oncotarget; 2016 Aug; 7(33):53679-53701. PubMed ID: 27447561
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Enhancer polymorphisms at the IKZF1 susceptibility locus for acute lymphoblastic leukemia impact B-cell proliferation and differentiation in both Down syndrome and non-Down syndrome genetic backgrounds.
    Gant VU; Junco JJ; Terrell M; Rashid R; Rabin KR
    PLoS One; 2021; 16(1):e0244863. PubMed ID: 33411777
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phenotypic and Functional Alterations of Hematopoietic Stem and Progenitor Cells in an In Vitro Leukemia-Induced Microenvironment.
    Vernot JP; Bonilla X; Rodriguez-Pardo V; Vanegas NP
    Int J Mol Sci; 2017 Feb; 18(2):. PubMed ID: 28216566
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.