BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

446 related articles for article (PubMed ID: 27867187)

  • 1. Crosstalk of ROS/RNS and autophagy in silibinin-induced apoptosis of MCF-7 human breast cancer cells in vitro.
    Zheng N; Liu L; Liu WW; Li F; Hayashi T; Tashiro SI; Onodera S; Ikejima T
    Acta Pharmacol Sin; 2017 Feb; 38(2):277-289. PubMed ID: 27867187
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Silibinin protects rat pancreatic β-cell through up-regulation of estrogen receptors' signaling against amylin- or Aβ
    Yang J; Sun Y; Xu F; Liu W; Hayashi T; Hattori S; Ushiki-Kaku Y; Onodera S; Tashiro SI; Ikejima T
    Phytother Res; 2019 Apr; 33(4):998-1009. PubMed ID: 30729588
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Silibinin induced-autophagic and apoptotic death is associated with an increase in reactive oxygen and nitrogen species in HeLa cells.
    Fan S; Li L; Chen S; Yu Y; Qi M; Tashiro S; Onodera S; Ikejima T
    Free Radic Res; 2011 Nov; 45(11-12):1307-24. PubMed ID: 21875385
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ERα down-regulation plays a key role in silibinin-induced autophagy and apoptosis in human breast cancer MCF-7 cells.
    Zheng N; Zhang P; Huang H; Liu W; Hayashi T; Zang L; Zhang Y; Liu L; Xia M; Tashiro S; Onodera S; Ikejima T
    J Pharmacol Sci; 2015 Jul; 128(3):97-107. PubMed ID: 26117209
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Estrogen receptors participate in silibinin-caused nuclear translocation of apoptosis-inducing factor in human breast cancer MCF-7 cells.
    Liu W; Ji Y; Sun Y; Si L; Fu J; Hayashi T; Onodera S; Ikejima T
    Arch Biochem Biophys; 2020 Aug; 689():108458. PubMed ID: 32524997
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The presence of Estrogen Receptor β modulates the response of breast cancer cells to therapeutic agents.
    Pons DG; Torrens-Mas M; Nadal-Serrano M; Sastre-Serra J; Roca P; Oliver J
    Int J Biochem Cell Biol; 2015 Sep; 66():85-94. PubMed ID: 26232188
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of ROS in the protective effect of silibinin on sodium nitroprusside-induced apoptosis in rat pheochromocytoma PC12 cells.
    Liu B; Yang P; Ye Y; Zhou Y; Li L; Tashiro S; Onodera S; Ikejima T
    Free Radic Res; 2011 Jul; 45(7):835-47. PubMed ID: 21568648
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ERβ up-regulation was involved in silibinin-induced growth inhibition of human breast cancer MCF-7 cells.
    Zheng N; Liu L; Liu W; Zhang P; Huang H; Zang L; Hayashi T; Tashiro S; Onodera S; Xia M; Ikejima T
    Arch Biochem Biophys; 2016 Feb; 591():141-9. PubMed ID: 26767948
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Silibinin induced autophagic and apoptotic cell death in HT1080 cells through a reactive oxygen species pathway.
    Duan W; Jin X; Li Q; Tashiro S; Onodera S; Ikejima T
    J Pharmacol Sci; 2010; 113(1):48-56. PubMed ID: 20431246
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ER alpha selective chromone, isoxazolylchromones, induces ROS-mediated cell death without autophagy.
    Kaushik S; Sanawar R; Lekshmi A; Chandrasekhar L; Nair M; Bhatnagar S; Santhoshkumar TR
    Chem Biol Drug Des; 2019 Jul; 94(1):1352-1367. PubMed ID: 31066219
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Silibinin-induced mitochondria fission leads to mitophagy, which attenuates silibinin-induced apoptosis in MCF-7 and MDA-MB-231 cells.
    Si L; Fu J; Liu W; Hayashi T; Mizuno K; Hattori S; Fujisaki H; Onodera S; Ikejima T
    Arch Biochem Biophys; 2020 May; 685():108284. PubMed ID: 32014401
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Silibinin, a natural flavonoid, induces autophagy via ROS-dependent mitochondrial dysfunction and loss of ATP involving BNIP3 in human MCF7 breast cancer cells.
    Jiang K; Wang W; Jin X; Wang Z; Ji Z; Meng G
    Oncol Rep; 2015 Jun; 33(6):2711-8. PubMed ID: 25891311
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Autophagy inhibition enhances silibinin-induced apoptosis by regulating reactive oxygen species production in human prostate cancer PC-3 cells.
    Kim SH; Kim KY; Yu SN; Park SK; Choi HD; Ji JH; Ahn SC
    Biochem Biophys Res Commun; 2015 Dec 4-11; 468(1-2):151-6. PubMed ID: 26522224
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Silibinin activated p53 and induced autophagic death in human fibrosarcoma HT1080 cells via reactive oxygen species-p38 and c-Jun N-terminal kinase pathways.
    Duan WJ; Li QS; Xia MY; Tashiro S; Onodera S; Ikejima T
    Biol Pharm Bull; 2011; 34(1):47-53. PubMed ID: 21212516
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Silibinin induces the generation of nitric oxide in human breast cancer MCF-7 cells.
    Wang HJ; Wei XF; Jiang YY; Huang H; Yang Y; Fan SM; Zang LH; Tashiro S; Onodera S; Ikejima T
    Free Radic Res; 2010 May; 44(5):577-84. PubMed ID: 20370556
    [TBL] [Abstract][Full Text] [Related]  

  • 16. P53 activation plays a crucial role in silibinin induced ROS generation via PUMA and JNK.
    Fan S; Qi M; Yu Y; Li L; Yao G; Tashiro S; Onodera S; Ikejima T
    Free Radic Res; 2012 Mar; 46(3):310-9. PubMed ID: 22283740
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Energy deprivation by silibinin in colorectal cancer cells: a double-edged sword targeting both apoptotic and autophagic machineries.
    Raina K; Agarwal C; Wadhwa R; Serkova NJ; Agarwal R
    Autophagy; 2013 May; 9(5):697-713. PubMed ID: 23445752
    [TBL] [Abstract][Full Text] [Related]  

  • 18. P53-mediated GSH depletion enhanced the cytotoxicity of NO in silibinin-treated human cervical carcinoma HeLa cells.
    Fan S; Yu Y; Qi M; Sun Z; Li L; Yao G; Tashiro S; Onodera S; Ikejima T
    Free Radic Res; 2012 Sep; 46(9):1082-92. PubMed ID: 22607092
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Silibinin induces cell death through reactive oxygen species-dependent downregulation of notch-1/ERK/Akt signaling in human breast cancer cells.
    Kim TH; Woo JS; Kim YK; Kim KH
    J Pharmacol Exp Ther; 2014 May; 349(2):268-78. PubMed ID: 24472723
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Silibinin triggers apoptotic signaling pathways and autophagic survival response in human colon adenocarcinoma cells and their derived metastatic cells.
    Kauntz H; Bousserouel S; Gossé F; Raul F
    Apoptosis; 2011 Oct; 16(10):1042-53. PubMed ID: 21779837
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.