BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

372 related articles for article (PubMed ID: 27869160)

  • 1. Pot1 OB-fold mutations unleash telomere instability to initiate tumorigenesis.
    Gu P; Wang Y; Bisht KK; Wu L; Kukova L; Smith EM; Xiao Y; Bailey SM; Lei M; Nandakumar J; Chang S
    Oncogene; 2017 Apr; 36(14):1939-1951. PubMed ID: 27869160
    [TBL] [Abstract][Full Text] [Related]  

  • 2. POT1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombination.
    He H; Multani AS; Cosme-Blanco W; Tahara H; Ma J; Pathak S; Deng Y; Chang S
    EMBO J; 2006 Nov; 25(21):5180-90. PubMed ID: 17053789
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Loss of hPot1 function leads to telomere instability and a cut-like phenotype.
    Veldman T; Etheridge KT; Counter CM
    Curr Biol; 2004 Dec; 14(24):2264-70. PubMed ID: 15620654
    [TBL] [Abstract][Full Text] [Related]  

  • 4. POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia.
    Ramsay AJ; Quesada V; Foronda M; Conde L; Martínez-Trillos A; Villamor N; Rodríguez D; Kwarciak A; Garabaya C; Gallardo M; López-Guerra M; López-Guillermo A; Puente XS; Blasco MA; Campo E; López-Otín C
    Nat Genet; 2013 May; 45(5):526-30. PubMed ID: 23502782
    [TBL] [Abstract][Full Text] [Related]  

  • 5. POT1 mutations cause differential effects on telomere length leading to opposing disease phenotypes.
    Zade NH; Khattar E
    J Cell Physiol; 2023 Jun; 238(6):1237-1255. PubMed ID: 37183325
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Critical role of the POT1 OB domain in maintaining genomic stability.
    Pandita TK
    Oncogene; 2017 Apr; 36(14):1908-1910. PubMed ID: 27869169
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Germline mutations in Protection of Telomeres 1 in two families with Hodgkin lymphoma.
    McMaster ML; Sun C; Landi MT; Savage SA; Rotunno M; Yang XR; Jones K; Vogt A; Hutchinson A; Zhu B; Wang M; Hicks B; Thirunavukarason A; Stewart DR; Koutros S; Goldstein AM; Chanock SJ; Caporaso NE; Tucker MA; Goldin LR; Liu Y
    Br J Haematol; 2018 May; 181(3):372-377. PubMed ID: 29693246
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Distinct requirements for Pot1 in limiting telomere length and maintaining chromosome stability.
    Bunch JT; Bae NS; Leonardi J; Baumann P
    Mol Cell Biol; 2005 Jul; 25(13):5567-78. PubMed ID: 15964812
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection.
    Lei M; Podell ER; Cech TR
    Nat Struct Mol Biol; 2004 Dec; 11(12):1223-9. PubMed ID: 15558049
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres.
    Wu L; Multani AS; He H; Cosme-Blanco W; Deng Y; Deng JM; Bachilo O; Pathak S; Tahara H; Bailey SM; Deng Y; Behringer RR; Chang S
    Cell; 2006 Jul; 126(1):49-62. PubMed ID: 16839876
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres.
    Hockemeyer D; Daniels JP; Takai H; de Lange T
    Cell; 2006 Jul; 126(1):63-77. PubMed ID: 16839877
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The OB-fold domain 1 of human POT1 recognizes both telomeric and non-telomeric DNA motifs.
    Choi KH; Lakamp-Hawley AS; Kolar C; Yan Y; Borgstahl GEO; Ouellette MM
    Biochimie; 2015 Aug; 115():17-27. PubMed ID: 25934589
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Functional diversity of human protection of telomeres 1 isoforms in telomere protection and cellular senescence.
    Yang Q; Zhang R; Horikawa I; Fujita K; Afshar Y; Kokko A; Laiho P; Aaltonen LA; Harris CC
    Cancer Res; 2007 Dec; 67(24):11677-86. PubMed ID: 18089797
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human shelterin protein POT1 prevents severe telomere instability induced by homology-directed DNA repair.
    Glousker G; Briod AS; Quadroni M; Lingner J
    EMBO J; 2020 Dec; 39(23):e104500. PubMed ID: 33073402
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PTOP interacts with POT1 and regulates its localization to telomeres.
    Liu D; Safari A; O'Connor MS; Chan DW; Laegeler A; Qin J; Songyang Z
    Nat Cell Biol; 2004 Jul; 6(7):673-80. PubMed ID: 15181449
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Protection of telomeres 1 (POT1) of Pinus tabuliformis bound the telomere ssDNA.
    Luo M; Teng X; Wang B; Zhang J; Liu Y; Liu D; Li H; Lu H
    Tree Physiol; 2020 Jan; 40(1):119-127. PubMed ID: 31860719
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dysfunctional mammalian telomeres join with DNA double-strand breaks.
    Bailey SM; Cornforth MN; Ullrich RL; Goodwin EH
    DNA Repair (Amst); 2004 Apr; 3(4):349-57. PubMed ID: 15010310
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination.
    Mateos-Gomez PA; Gong F; Nair N; Miller KM; Lazzerini-Denchi E; Sfeir A
    Nature; 2015 Feb; 518(7538):254-7. PubMed ID: 25642960
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Spontaneous telomere to telomere fusions occur in unperturbed fission yeast cells.
    Almeida H; Godinho Ferreira M
    Nucleic Acids Res; 2013 Mar; 41(5):3056-67. PubMed ID: 23335786
    [TBL] [Abstract][Full Text] [Related]  

  • 20. POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes end.
    Hockemeyer D; Sfeir AJ; Shay JW; Wright WE; de Lange T
    EMBO J; 2005 Jul; 24(14):2667-78. PubMed ID: 15973431
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.