These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 27872070)

  • 1. Estimation of the In Vivo MIC of Cipargamin in Uncomplicated Plasmodium falciparum Malaria.
    Hien TT; White NJ; Thuy-Nhien NT; Hoa NT; Thuan PD; Tarning J; Nosten F; Magnusson B; Jain JP; Hamed K
    Antimicrob Agents Chemother; 2017 Feb; 61(2):. PubMed ID: 27872070
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Spiroindolone KAE609 for falciparum and vivax malaria.
    White NJ; Pukrittayakamee S; Phyo AP; Rueangweerayut R; Nosten F; Jittamala P; Jeeyapant A; Jain JP; Lefèvre G; Li R; Magnusson B; Diagana TT; Leong FJ
    N Engl J Med; 2014 Jul; 371(5):403-10. PubMed ID: 25075833
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hepatic safety and tolerability of cipargamin (KAE609), in adult patients with Plasmodium falciparum malaria: a randomized, phase II, controlled, dose-escalation trial in sub-Saharan Africa.
    Ndayisaba G; Yeka A; Asante KP; Grobusch MP; Karita E; Mugerwa H; Asiimwe S; Oduro A; Fofana B; Doumbia S; Jain JP; Barsainya S; Kullak-Ublick GA; Su G; Schmitt EK; Csermak K; Gandhi P; Hughes D
    Malar J; 2021 Dec; 20(1):478. PubMed ID: 34930267
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Defining the Antimalarial Activity of Cipargamin in Healthy Volunteers Experimentally Infected with Blood-Stage Plasmodium falciparum.
    McCarthy JS; Abd-Rahman AN; Collins KA; Marquart L; Griffin P; Kümmel A; Fuchs A; Winnips C; Mishra V; Csermak-Renner K; Jain JP; Gandhi P
    Antimicrob Agents Chemother; 2021 Jan; 65(2):. PubMed ID: 33199389
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Efficacy of Cipargamin (KAE609) in a Randomized, Phase II Dose-Escalation Study in Adults in Sub-Saharan Africa With Uncomplicated Plasmodium falciparum Malaria.
    Schmitt EK; Ndayisaba G; Yeka A; Asante KP; Grobusch MP; Karita E; Mugerwa H; Asiimwe S; Oduro A; Fofana B; Doumbia S; Su G; Csermak Renner K; Venishetty VK; Sayyed S; Straimer J; Demin I; Barsainya S; Boulton C; Gandhi P
    Clin Infect Dis; 2022 May; 74(10):1831-1839. PubMed ID: 34410358
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Arterolane maleate plus piperaquine phosphate for treatment of uncomplicated Plasmodium falciparum malaria: a comparative, multicenter, randomized clinical trial.
    Valecha N; Krudsood S; Tangpukdee N; Mohanty S; Sharma SK; Tyagi PK; Anvikar A; Mohanty R; Rao BS; Jha AC; Shahi B; Singh JP; Roy A; Kaur P; Kothari M; Mehta S; Gautam A; Paliwal JK; Arora S; Saha N
    Clin Infect Dis; 2012 Sep; 55(5):663-71. PubMed ID: 22586253
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Antimalarial activity of artefenomel (OZ439), a novel synthetic antimalarial endoperoxide, in patients with Plasmodium falciparum and Plasmodium vivax malaria: an open-label phase 2 trial.
    Phyo AP; Jittamala P; Nosten FH; Pukrittayakamee S; Imwong M; White NJ; Duparc S; Macintyre F; Baker M; Möhrle JJ
    Lancet Infect Dis; 2016 Jan; 16(1):61-69. PubMed ID: 26448141
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The early preclinical and clinical development of cipargamin (KAE609), a novel antimalarial compound.
    Bouwman SA; Zoleko-Manego R; Renner KC; Schmitt EK; Mombo-Ngoma G; Grobusch MP
    Travel Med Infect Dis; 2020; 36():101765. PubMed ID: 32561392
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Assessment
    Yipsirimetee A; Chiewpoo P; Tripura R; Lek D; Day NPJ; Dondorp AM; Pukrittayakamee S; White NJ; Chotivanich K
    Antimicrob Agents Chemother; 2022 Mar; 66(3):e0148121. PubMed ID: 34978886
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Safety, tolerability, pharmacokinetics, and antimalarial efficacy of a novel Plasmodium falciparum ATP4 inhibitor SJ733: a first-in-human and induced blood-stage malaria phase 1a/b trial.
    Gaur AH; McCarthy JS; Panetta JC; Dallas RH; Woodford J; Tang L; Smith AM; Stewart TB; Branum KC; Freeman BB; Patel ND; John E; Chalon S; Ost S; Heine RN; Richardson JL; Christensen R; Flynn PM; Van Gessel Y; Mitasev B; Möhrle JJ; Gusovsky F; Bebrevska L; Guy RK
    Lancet Infect Dis; 2020 Aug; 20(8):964-975. PubMed ID: 32275867
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pharmacokinetics and pharmacodynamics of arterolane maleate following multiple oral doses in adult patients with P. falciparum malaria.
    Gautam A; Ahmed T; Sharma P; Varshney B; Kothari M; Saha N; Roy A; Moehrle JJ; Paliwal J
    J Clin Pharmacol; 2011 Nov; 51(11):1519-28. PubMed ID: 21148048
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A randomised, double-blind clinical phase II trial of the efficacy, safety, tolerability and pharmacokinetics of a single dose combination treatment with artefenomel and piperaquine in adults and children with uncomplicated Plasmodium falciparum malaria.
    Macintyre F; Adoke Y; Tiono AB; Duong TT; Mombo-Ngoma G; Bouyou-Akotet M; Tinto H; Bassat Q; Issifou S; Adamy M; Demarest H; Duparc S; Leroy D; Laurijssens BE; Biguenet S; Kibuuka A; Tshefu AK; Smith M; Foster C; Leipoldt I; Kremsner PG; Phuc BQ; Ouedraogo A; Ramharter M;
    BMC Med; 2017 Oct; 15(1):181. PubMed ID: 28988541
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Assessment of Efficacy and Safety of Arterolane Maleate-Piperaquine Phosphate Dispersible Tablets in Comparison With Artemether-Lumefantrine Dispersible Tablets in Pediatric Patients With Acute Uncomplicated Plasmodium falciparum Malaria: A Phase 3, Randomized, Multicenter Trial in India and Africa.
    Toure OA; Mwapasa V; Sagara I; Gaye O; Thompson R; Maheshwar AV; Mishra P; Behra N; Tshefu AK; Das RR; Anvikar AR; Sharma P; Roy A; Sharma SK; Nasa A; Jalali RK; Valecha N;
    Clin Infect Dis; 2017 Oct; 65(10):1711-1720. PubMed ID: 29020247
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antimalarial Activity of KAF156 in Falciparum and Vivax Malaria.
    White NJ; Duong TT; Uthaisin C; Nosten F; Phyo AP; Hanboonkunupakarn B; Pukrittayakamee S; Jittamala P; Chuthasmit K; Cheung MS; Feng Y; Li R; Magnusson B; Sultan M; Wieser D; Xun X; Zhao R; Diagana TT; Pertel P; Leong FJ
    N Engl J Med; 2016 Sep; 375(12):1152-60. PubMed ID: 27653565
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Semimechanistic Pharmacokinetic and Pharmacodynamic Modeling of Piperaquine in a Volunteer Infection Study with Plasmodium falciparum Blood-Stage Malaria.
    Wattanakul T; Baker M; Mohrle J; McWhinney B; Hoglund RM; McCarthy JS; Tarning J
    Antimicrob Agents Chemother; 2021 Mar; 65(4):. PubMed ID: 33468477
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A randomized feasibility trial comparing four antimalarial drug regimens to induce
    Reuling IJ; van de Schans LA; Coffeng LE; Lanke K; Meerstein-Kessel L; Graumans W; van Gemert GJ; Teelen K; Siebelink-Stoter R; van de Vegte-Bolmer M; de Mast Q; van der Ven AJ; Ivinson K; Hermsen CC; de Vlas S; Bradley J; Collins KA; Ockenhouse CF; McCarthy J; Sauerwein RW; Bousema T
    Elife; 2018 Feb; 7():. PubMed ID: 29482720
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterising the blood-stage antimalarial activity of pyronaridine in healthy volunteers experimentally infected with Plasmodium falciparum.
    Barber BE; Webster R; Potter AJ; Llewellyn S; Sahai N; Leelasena I; Mathison S; Kuritz K; Flynn J; Chalon S; Marrast AC; Gobeau N; Moehrle JJ
    Int J Antimicrob Agents; 2024 Jul; 64(1):107196. PubMed ID: 38734217
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pharmacokinetic/pharmacodynamic modelling of the antimalarial effect of Actelion-451840 in an induced blood stage malaria study in healthy subjects.
    Krause A; Dingemanse J; Mathis A; Marquart L; Möhrle JJ; McCarthy JS
    Br J Clin Pharmacol; 2016 Aug; 82(2):412-21. PubMed ID: 27062080
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A Single-Dose Combination Study with the Experimental Antimalarials Artefenomel and DSM265 To Determine Safety and Antimalarial Activity against Blood-Stage Plasmodium falciparum in Healthy Volunteers.
    McCarthy JS; Rückle T; Elliott SL; Ballard E; Collins KA; Marquart L; Griffin P; Chalon S; Möhrle JJ
    Antimicrob Agents Chemother; 2019 Dec; 64(1):. PubMed ID: 31685476
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A first-in-human randomized, double-blind, placebo-controlled, single- and multiple-ascending oral dose study of novel antimalarial Spiroindolone KAE609 (Cipargamin) to assess its safety, tolerability, and pharmacokinetics in healthy adult volunteers.
    Leong FJ; Li R; Jain JP; Lefèvre G; Magnusson B; Diagana TT; Pertel P
    Antimicrob Agents Chemother; 2014 Oct; 58(10):6209-14. PubMed ID: 25114127
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.