BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 27874013)

  • 1. Crystal structure of FabZ-ACP complex reveals a dynamic seesaw-like catalytic mechanism of dehydratase in fatty acid biosynthesis.
    Zhang L; Xiao J; Xu J; Fu T; Cao Z; Zhu L; Chen HZ; Shen X; Jiang H; Zhang L
    Cell Res; 2016 Dec; 26(12):1330-1344. PubMed ID: 27874013
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A back-door Phenylalanine coordinates the stepwise hexameric loading of acyl carrier protein by the fatty acid biosynthesis enzyme β-hydroxyacyl-acyl carrier protein dehydratase (FabZ).
    Shen S; Hang X; Zhuang J; Zhang L; Bi H; Zhang L
    Int J Biol Macromol; 2019 May; 128():5-11. PubMed ID: 30677439
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Trapping the dynamic acyl carrier protein in fatty acid biosynthesis.
    Nguyen C; Haushalter RW; Lee DJ; Markwick PR; Bruegger J; Caldara-Festin G; Finzel K; Jackson DR; Ishikawa F; O'Dowd B; McCammon JA; Opella SJ; Tsai SC; Burkart MD
    Nature; 2014 Jan; 505(7483):427-31. PubMed ID: 24362570
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural basis for catalytic and inhibitory mechanisms of beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ).
    Zhang L; Liu W; Hu T; Du L; Luo C; Chen K; Shen X; Jiang H
    J Biol Chem; 2008 Feb; 283(9):5370-9. PubMed ID: 18093984
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The structure of (3R)-hydroxyacyl-acyl carrier protein dehydratase (FabZ) from Pseudomonas aeruginosa.
    Kimber MS; Martin F; Lu Y; Houston S; Vedadi M; Dharamsi A; Fiebig KM; Schmid M; Rock CO
    J Biol Chem; 2004 Dec; 279(50):52593-602. PubMed ID: 15371447
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural and dynamical rationale for fatty acid unsaturation in
    Dodge GJ; Patel A; Jaremko KL; McCammon JA; Smith JL; Burkart MD
    Proc Natl Acad Sci U S A; 2019 Apr; 116(14):6775-6783. PubMed ID: 30872475
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Campylobacter jejuni fatty acid synthase II: structural and functional analysis of beta-hydroxyacyl-ACP dehydratase (FabZ).
    Kirkpatrick AS; Yokoyama T; Choi KJ; Yeo HJ
    Biochem Biophys Res Commun; 2009 Mar; 380(2):407-12. PubMed ID: 19280690
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of isoflavonoids as inhibitors of β-hydroxyacyl-acyl carrier protein dehydratase (FabZ) from Moraxella catarrhalis: Kinetics, spectroscopic, thermodynamics and in silico studies.
    Kumar V; Sharma A; Pratap S; Kumar P
    Biochim Biophys Acta Gen Subj; 2018 Mar; 1862(3):726-744. PubMed ID: 29092780
    [TBL] [Abstract][Full Text] [Related]  

  • 9. β-Hydroxyacyl-acyl Carrier Protein Dehydratase (FabZ) from Francisella tularensis and Yersinia pestis: Structure Determination, Enzymatic Characterization, and Cross-Inhibition Studies.
    McGillick BE; Kumaran D; Vieni C; Swaminathan S
    Biochemistry; 2016 Feb; 55(7):1091-9. PubMed ID: 26818694
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A new beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) from Helicobacter pylori: Molecular cloning, enzymatic characterization, and structural modeling.
    Liu W; Luo C; Han C; Peng S; Yang Y; Yue J; Shen X; Jiang H
    Biochem Biophys Res Commun; 2005 Aug; 333(4):1078-86. PubMed ID: 15967411
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Modeling holo-ACP:DH and holo-ACP:KR complexes of modular polyketide synthases: a docking and molecular dynamics study.
    Anand S; Mohanty D
    BMC Struct Biol; 2012 May; 12():10. PubMed ID: 22639887
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification, characterization, and inhibition of Plasmodium falciparum beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ).
    Sharma SK; Kapoor M; Ramya TN; Kumar S; Kumar G; Modak R; Sharma S; Surolia N; Surolia A
    J Biol Chem; 2003 Nov; 278(46):45661-71. PubMed ID: 12930838
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Crystal structures of acyl carrier protein in complex with two catalytic partners show a dynamic role in cellular metabolism.
    Newmister SA; Sherman DH
    Chembiochem; 2014 May; 15(8):1079-81. PubMed ID: 24771327
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Helicobacter pylori acyl carrier protein: expression, purification, and its interaction with beta-hydroxyacyl-ACP dehydratase.
    Liu W; Du L; Zhang L; Chen J; Shen X; Jiang H
    Protein Expr Purif; 2007 Mar; 52(1):74-81. PubMed ID: 17049879
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sunflower (Helianthus annuus) fatty acid synthase complex: β-hydroxyacyl-[acyl carrier protein] dehydratase genes.
    González-Thuillier I; Venegas-Calerón M; Sánchez R; Garcés R; von Wettstein-Knowles P; Martínez-Force E
    Planta; 2016 Feb; 243(2):397-410. PubMed ID: 26433735
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fused dimerization increases expression, solubility, and activity of bacterial dehydratase enzymes.
    Rullán-Lind C; Pietri RB; Vázquez-Cintrón M; Baerga-Ortiz A
    Protein Sci; 2018 May; 27(5):969-975. PubMed ID: 29520922
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interactions of the acyl chain with the Saccharomyces cerevisiae acyl carrier protein.
    Perez DR; Leibundgut M; Wider G
    Biochemistry; 2015 Apr; 54(13):2205-13. PubMed ID: 25774789
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Roles of the FabA and FabZ beta-hydroxyacyl-acyl carrier protein dehydratases in Escherichia coli fatty acid biosynthesis.
    Heath RJ; Rock CO
    J Biol Chem; 1996 Nov; 271(44):27795-801. PubMed ID: 8910376
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III activity is inhibited by phosphorylation on a single threonine residue.
    Veyron-Churlet R; Molle V; Taylor RC; Brown AK; Besra GS; Zanella-Cléon I; Fütterer K; Kremer L
    J Biol Chem; 2009 Mar; 284(10):6414-24. PubMed ID: 19074144
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure and dynamics of human and bacterial acyl carrier proteins and their interactions with fatty acid synthesis proteins.
    Park J; Lee Y; Cheon D; Kim Y
    Biochem Biophys Res Commun; 2019 Sep; 516(4):1183-1189. PubMed ID: 31296387
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.