BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

300 related articles for article (PubMed ID: 27875314)

  • 1. Receptor MER Tyrosine Kinase Proto-oncogene (MERTK) Is Not Required for Transfer of Bis-retinoids to the Retinal Pigmented Epithelium.
    Palczewska G; Maeda A; Golczak M; Arai E; Dong Z; Perusek L; Kevany B; Palczewski K
    J Biol Chem; 2016 Dec; 291(52):26937-26949. PubMed ID: 27875314
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration.
    Lenis TL; Hu J; Ng SY; Jiang Z; Sarfare S; Lloyd MB; Esposito NJ; Samuel W; Jaworski C; Bok D; Finnemann SC; Radeke MJ; Redmond TM; Travis GH; Radu RA
    Proc Natl Acad Sci U S A; 2018 Nov; 115(47):E11120-E11127. PubMed ID: 30397118
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MERTK signaling in the retinal pigment epithelium regulates the tyrosine phosphorylation of GDP dissociation inhibitor alpha from the GDI/CHM family of RAB GTPase effectors.
    Shelby SJ; Feathers KL; Ganios AM; Jia L; Miller JM; Thompson DA
    Exp Eye Res; 2015 Nov; 140():28-40. PubMed ID: 26283020
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mertk drives myosin II redistribution during retinal pigment epithelial phagocytosis.
    Strick DJ; Feng W; Vollrath D
    Invest Ophthalmol Vis Sci; 2009 May; 50(5):2427-35. PubMed ID: 19117932
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cleavage of Mer tyrosine kinase (MerTK) from the cell surface contributes to the regulation of retinal phagocytosis.
    Law AL; Parinot C; Chatagnon J; Gravez B; Sahel JA; Bhattacharya SS; Nandrot EF
    J Biol Chem; 2015 Feb; 290(8):4941-4952. PubMed ID: 25538233
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tyro3 Modulates Mertk-Associated Retinal Degeneration.
    Vollrath D; Yasumura D; Benchorin G; Matthes MT; Feng W; Nguyen NM; Sedano CD; Calton MA; LaVail MM
    PLoS Genet; 2015 Dec; 11(12):e1005723. PubMed ID: 26656104
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mertk triggers uptake of photoreceptor outer segments during phagocytosis by cultured retinal pigment epithelial cells.
    Feng W; Yasumura D; Matthes MT; LaVail MM; Vollrath D
    J Biol Chem; 2002 May; 277(19):17016-22. PubMed ID: 11861639
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Bisretinoids mediate light sensitivity resulting in photoreceptor cell degeneration in mice lacking the receptor tyrosine kinase Mer.
    Zhao J; Ueda K; Riera M; Kim HJ; Sparrow JR
    J Biol Chem; 2018 Dec; 293(50):19400-19410. PubMed ID: 30352873
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Expression pattern of Ccr2 and Cx3cr1 in inherited retinal degeneration.
    Kohno H; Koso H; Okano K; Sundermeier TR; Saito S; Watanabe S; Tsuneoka H; Sakai T
    J Neuroinflammation; 2015 Oct; 12():188. PubMed ID: 26458944
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Retinal pigment epithelial cells use a MerTK-dependent mechanism to limit the phagocytic particle binding activity of αvβ5 integrin.
    Nandrot EF; Silva KE; Scelfo C; Finnemann SC
    Biol Cell; 2012 Jun; 104(6):326-41. PubMed ID: 22289110
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular characterization and functional analysis of phagocytosis by human embryonic stem cell-derived RPE cells using a novel human retinal assay.
    Carr AJ; Vugler A; Lawrence J; Chen LL; Ahmado A; Chen FK; Semo M; Gias C; da Cruz L; Moore HD; Walsh J; Coffey PJ
    Mol Vis; 2009; 15():283-95. PubMed ID: 19204785
    [TBL] [Abstract][Full Text] [Related]  

  • 12. UNC569-induced Morphological Changes in Pigment Epithelia and Photoreceptor Cells in the Retina through MerTK Inhibition in Mice.
    Sayama A; Okado K; Nakamura K; Kawaguchi T; Iguchi T; Makino T; Yabe K; Kai K; Mori K
    Toxicol Pathol; 2018 Feb; 46(2):193-201. PubMed ID: 29310530
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MERTK interactions with SH2-domain proteins in the retinal pigment epithelium.
    Shelby SJ; Colwill K; Dhe-Paganon S; Pawson T; Thompson DA
    PLoS One; 2013; 8(2):e53964. PubMed ID: 23390493
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Limited roles of Rdh8, Rdh12, and Abca4 in all-trans-retinal clearance in mouse retina.
    Maeda A; Golczak M; Maeda T; Palczewski K
    Invest Ophthalmol Vis Sci; 2009 Nov; 50(11):5435-43. PubMed ID: 19553623
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inflammation of the retinal pigment epithelium drives early-onset photoreceptor degeneration in
    Mercau ME; Akalu YT; Mazzoni F; Gyimesi G; Alberto EJ; Kong Y; Hafler BP; Finnemann SC; Rothlin CV; Ghosh S
    Sci Adv; 2023 Jan; 9(3):eade9459. PubMed ID: 36662852
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Di-retinoid-pyridinium-ethanolamine (A2E) Accumulation and the Maintenance of the Visual Cycle Are Independent of Atg7-mediated Autophagy in the Retinal Pigmented Epithelium.
    Perusek L; Sahu B; Parmar T; Maeno H; Arai E; Le YZ; Subauste CS; Chen Y; Palczewski K; Maeda A
    J Biol Chem; 2015 Nov; 290(48):29035-44. PubMed ID: 26468292
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An RCS-like retinal dystrophy phenotype in mer knockout mice.
    Duncan JL; LaVail MM; Yasumura D; Matthes MT; Yang H; Trautmann N; Chappelow AV; Feng W; Earp HS; Matsushima GK; Vollrath D
    Invest Ophthalmol Vis Sci; 2003 Feb; 44(2):826-38. PubMed ID: 12556419
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Essential diurnal Rac1 activation during retinal phagocytosis requires αvβ5 integrin but not tyrosine kinases focal adhesion kinase or Mer tyrosine kinase.
    Mao Y; Finnemann SC
    Mol Biol Cell; 2012 Mar; 23(6):1104-14. PubMed ID: 22262456
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacological inhibition of MERTK induces in vivo retinal degeneration: a multimodal imaging ocular safety assessment.
    Hamm G; Maglennon G; Williamson B; Macdonald R; Doherty A; Jones S; Harris J; Blades J; Harmer AR; Barton P; Rawlins PB; Smith P; Winter-Holt J; McMurray L; Johansson J; Fitzpatrick P; McCoull W; Coen M
    Arch Toxicol; 2022 Feb; 96(2):613-624. PubMed ID: 34973110
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Microglia Inhibition Delays Retinal Degeneration Due to MerTK Phagocytosis Receptor Deficiency.
    Lew DS; Mazzoni F; Finnemann SC
    Front Immunol; 2020; 11():1463. PubMed ID: 32765507
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.